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Is there an association between glaucoma and capillaroscopy in patients with systemic sclerosis?

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Abstract

Purpose

To evaluate the relationship between glaucoma diagnosis and the nailfold capillaroscopy pattern in patients with systemic sclerosis.

Methods

An observational study in a cohort of patients with SSc was conducted. Patients with at least one nailfold videocapillaroscopy and one ophthalmology examination at the same year were included. Data collected were: age, sex; type of systemic sclerosis according to the degree of skin impairment, self-reported ethnicity, disease duration, current use and dosage of systemic corticosteroid, current use and dosage of bosentan®, intraocular pressure, central corneal thickness, diagnosis of glaucoma and capillaroscopy pattern.

Results

Thirty-one patients with systemic sclerosis were enrolled, 23% had glaucoma. There was no statistically significant association between glaucoma diagnosis and the capillaroscopic pattern (p = 0.86). There was also no significant difference (p = 0.66) regarding intraocular pressure between patients with mild (13.9 ± 3.8 mmHg) and severe capillaroscopic pattern (14.4 ± 2.8 mmHg). The odds ratio of glaucoma for severe capillaroscopic pattern compared to mild was 1.6 (95% confidence interval: 0.3–9.5).

Conclusion

Up to 23% of patients with SSc have glaucoma. The high prevalence of glaucoma in SSc suggests a possible systemic vascular disturbance as the cause. However, there seems to be no significant association between the capillaroscopy pattern and glaucoma in systemic sclerosis. Further research is required to improve the understanding of glaucoma in the context of systemic sclerosis.

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Authors and Affiliations

  1. Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brazil

    Beatriz Fiuza Gomes & Haroldo Vieira Moraes

  2. Hospital Federal de Bonsucesso, Rio de Janeiro, RJ, Brazil

    Beatriz Fiuza Gomes, Rebeca Souza & Thiago Valadão

  3. Universidade de São Paulo, São Paulo, SP, Brazil

    Newton Kara-Junior & Marcony R. Santhiago

Authors
  1. Beatriz Fiuza Gomes
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  2. Rebeca Souza
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  3. Thiago Valadão
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  4. Newton Kara-Junior
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  5. Haroldo Vieira Moraes
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  6. Marcony R. Santhiago
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Correspondence to Beatriz Fiuza Gomes.

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Gomes, B.F., Souza, R., Valadão, T. et al. Is there an association between glaucoma and capillaroscopy in patients with systemic sclerosis?. Int Ophthalmol 38, 251–256 (2018). https://doi.org/10.1007/s10792-017-0454-1

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  • DOI: https://doi.org/10.1007/s10792-017-0454-1

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