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International Ophthalmology

, Volume 38, Issue 1, pp 11–18 | Cite as

Treatment outcome in patients with presumed tubercular uveitis at a tertiary referral eye care centre in Singapore

  • Leslie Ang
  • Aera Kee
  • Tun Hang Yeo
  • V. G. Dinesh
  • Su Ling Ho
  • Stephen C. Teoh
  • Rupesh Agrawal
Original Paper

Abstract

Aim

To report the clinical features and outcome of patients with presumed tubercular uveitis (TBU).

Methods

Retrospective analysis of patients with presumed TBU at a tertiary referral eye care centre in Singapore between 2007 and 2012 was done. Main outcome measures were failure of complete resolution of uveitis or recurrence of inflammation.

Results

Fifty three patients with mean age of 44.18 ± 15.26 years with 54.72% being males were included. 19 (35.85%) had bilateral involvement, with panuveitis and anterior uveitis being the most common presentations. 36 (67.92%) patients received antitubercular therapy (ATT), and 28 received concurrent systemic steroids. 15 (28.30%) eyes of 11 (30.55%) patients in the ATT group and 4 (21.05%) eyes of 3 (17.64%) patients in the non-ATT group had treatment failure (p value = 0.51).

Conclusion

The use of ATT, with or without concurrent corticosteroid, may not have a statistically significant impact in improving treatment success in patients with presumed TBU.

Keywords

Antitubercular therapy Panuveitis Tubercular uveitis Steroids Tuberculosis 

Notes

Author’s contributions

LA was involved in the conceptualization of the study, data acquisition, analysis of data, and drafting and writing up of the manuscript. AK, YTH, and VGD were involved in the acquisition and analysis of the data. HSL, ST, and RA were involved in conceptualization of the study, writing up and editing of the manuscript.

Compliance with ethical standards

Conflict of interest

All authors certify that they have no affiliations with or involvement in any organization or entity with any financial interest (such as honoraria; educational grants; participation in speakers’ bureaus; membership, employment, consultancies, stock ownership, or other equity interest; and expert testimony or patent-licensing arrangements) or non-financial interest (such as personal or professional relationships, affiliations, knowledge, or beliefs) in the subject matter or materials discussed in this manuscript.

Supplementary material

10792_2016_401_MOESM1_ESM.xlsx (48 kb)
Supplementary material 1 (XLSX 48 kb)

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Copyright information

© Springer Science+Business Media Dordrecht 2016

Authors and Affiliations

  • Leslie Ang
    • 1
  • Aera Kee
    • 2
  • Tun Hang Yeo
    • 1
  • V. G. Dinesh
    • 3
  • Su Ling Ho
    • 1
  • Stephen C. Teoh
    • 1
    • 4
  • Rupesh Agrawal
    • 1
  1. 1.National Healthcare Group Eye InstituteTan Tock Seng HospitalSingaporeSingapore
  2. 2.Yong Loo Lin School of MedicineNational University of SingaporeSingaporeSingapore
  3. 3.Department of General MedicineTan Tock Seng HospitalSingaporeSingapore
  4. 4.Eagle Eye CentreSingaporeSingapore

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