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Characteristics of higher-order aberrations and anterior segment tomography in patients with pathologic myopia

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Abstract

Purpose

To investigate prospectively the characteristics in the higher-order aberrations and anterior segment tomography in patients with pathologic myopia.

Methods

One hundred and twelve consecutive highly myopic patients (mean age 43.4 ± 9.3 years, spherical equivalent of refractive error ≥8 D and an axial length ≥26.5 mm) were studied. Thirty-seven emmetropic individuals (mean age 37.0 ± 14.5 years, spherical equivalent of refractive error ≤ ±1 D) were analyzed as controls. The ocular and cornea higher-order aberrations were measured using a Hartmann–Shack wavefront sensor (KR-1W; Topcon Corporation, Tokyo, Japan). The crystalline lens rise, the angle-to-angle, and the white-to-white values were measured using anterior segment OCT (SS-1000; Tomey Corporation, Nagoya, Japan). The mean curvature of the anterior corneal surface, the thickness at the thinnest central corneal point, the location of the central corneal point, the corneal volume, the anterior chamber volume, and the anterior chamber depth were measured using the Pentacam HR (Oculus, Inc., Wetzlar, Germany).

Results

The ocular total higher-order aberration for 4-mm pupil, the ocular spherical aberrations, and internal spherical aberration for 6-mm pupil were significantly higher in highly myopic eyes than in the emmetropic controls. The crystalline lens rise was significantly smaller in highly myopic eyes than in the emmetropic controls. The anterior chamber depth and the anterior chamber volume were significantly larger in highly myopic eyes than in the emmetropic controls.

Conclusion

Highly myopic eyes had higher-order aberrations than emmetropic eyes because of the increasing internal aberrations.

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Acknowledgments

The authors thank Prof. Duco Hamasaki for his critical discussion and final manuscript revision.

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Authors and Affiliations

  1. Department of Ophthalmology and Visual Science, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8510, Japan

    Kaori Kasahara, Muka Moriyama & Kyoko Ohno-Matsui

  2. Department of Ophthalmology, Osaka University Graduate School of Medicine, Osaka, Japan

    Naoyuki Maeda, Takashi Fujikado & Mutsumi Fuchihata

  3. Clinical Research Center, Tokyo Medical and Dental University, Tokyo, Japan

    Makoto Tomita

Authors
  1. Kaori Kasahara
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  2. Naoyuki Maeda
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  3. Takashi Fujikado
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  4. Makoto Tomita
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  5. Muka Moriyama
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  6. Mutsumi Fuchihata
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  7. Kyoko Ohno-Matsui
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Correspondence to Kyoko Ohno-Matsui.

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Kasahara, K., Maeda, N., Fujikado, T. et al. Characteristics of higher-order aberrations and anterior segment tomography in patients with pathologic myopia. Int Ophthalmol 37, 1279–1288 (2017). https://doi.org/10.1007/s10792-016-0356-7

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  • DOI: https://doi.org/10.1007/s10792-016-0356-7

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