Abstract
To evaluate the approach to management of iatrogenic crystalline lens injury occurred during intravitreal injection (IVI). The patients who were managed operatively or followed-up without intervention after the iatrogenic lens injury due to IVI were included in the study. Capsular breaks remained either quiescent or resulted in cataract formation in the patients with inadvertent crystalline lens capsule damage. Phacoemulsification surgery was performed in patients with cataract formation with lower fluidic settings. A total of 9 cases included in the study. Seven cases underwent phacoemulsification with intraocular lens implantation. Two cases remained as quiescent lens injury during the follow-up. In 2 cases, dislocation of lens fragments occurred during phacoemulsification where pars plana vitrectomy was performed at the same session. After iatrogenic crystalline lens injury, capsular damage could remain quiescent or progress to cataract formation. Although phacoemulsification surgery can be performed with appropriate parameters, lens fragment dislocation can be observed in cases with traumatic lens damage secondary to IVI.
Similar content being viewed by others
References
Meyer CH, Rodrigues EB, Michels S, Mennel S, Schmidt JC, Helb HM, Hager A, Martinazzo M, Farah ME (2010) Incidence of damage to the crystalline lens during intravitreal injections. J Ocul Pharmacol Ther 26:491–495
Gragoudas ES, Adamis AP, Cunningham ET Jr, Feinsod M, Guyer DR (2004) VEGF inhibition study in Ocular Neovascularization Clinical Trial Group. Pegaptanib for neovascular age-related macular degeneration. N Engl J Med 351:2805–2816
Shima C, Sakaguchi H, Gomi F, Kamei M, Ikuno Y, Oshima Y, Sawa M, Tsujikawa M, Kusaka S, Tano Y (2008) Complications in patients after intravitreal injection of bevacizumab. Acta Ophthalmol 86:372–376
Fung AE, Rosenfeld PJ, Reichel E (2006) The International Intravitreal Bevacizumab Safety Survey: using the internet to assess drug safety worldwide. Br J Ophthalmol 90:1344–1349
Ladas ID, Karagiannis DA, Rouvas AA, Kotsolis AI, Liotsou A, Vergados I (2009) Safety of repeat intravitreal injections of bevacizumab versus ranibizumab: our experience after 2000 injections. Retina 29:313–318
Jonas JB, Spandau UH, Schlichtenbrede F (2008) Short-term complications of intravitreal injections of triamcinolone and bevacizumab. Eye 22:590–591
Khalifa YM, Pantanelli SM (2011) Quiescent posterior capsule trauma after intravitreal injection: implications for the cataract surgeon. J Cataract Refract Surg 37:1364
Saeed MU, Prasad S (2009) Management of cataract caused by inadvertent capsule penetration during intravitreal injection of ranibizumab. J Cataract Refract Surg 35:1857–1859
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Conflict of interest
No authors report conflict of interests.
Rights and permissions
About this article
Cite this article
Erdogan, G., Gunay, B.O., Unlu, C. et al. Management of iatrogenic crystalline lens injury occurred during intravitreal injection. Int Ophthalmol 36, 527–530 (2016). https://doi.org/10.1007/s10792-015-0156-5
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s10792-015-0156-5