Skip to main content

Advertisement

Log in

Parinaud’s oculoglandular syndrome revealing subclinical Rickettsia conorii infection

  • Case Report
  • Published:
International Ophthalmology Aims and scope Submit manuscript

Abstract

The purpose of this study was to report a case of Parinaud’s oculoglandular syndrome associated with subclinical Rickettsia conorii infection. We report a case of a 66-year-old male patient presented with unilateral persistent granulomatous conjunctivitis in the left eye and an ipsilateral preauricular lymphadenopathy without associated systemic features. Laboratory evaluation showed a positive indirect immunofluorescence antibody test for R. conorii. The patient received a 2-week course of oral doxycycline, with subsequent complete resolution of all his symptoms. Rickettsial disease should be considered in the differential diagnosis of oculoglandular syndrome with or without associated systemic symptoms in any patient living in or returning from a specific endemic area.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1

References

  1. Cassady JV, Culbertson CS (1953) Cat-scratch disease and Parinaud’s oculoglandular syndrome. Arch Ophthalmol 50:68–74

    Article  CAS  Google Scholar 

  2. Cunningham ET, Koehler JE (2000) Ocular bartonellosis. Am J Ophthalmol 130:340–349

    Article  CAS  PubMed  Google Scholar 

  3. Carithers HA (1985) Cat-scratch disease. An overview based on a study of 1,200 patients. Am J Dis Child 139:1124–1133

    Article  CAS  PubMed  Google Scholar 

  4. Martin X, Uffer S, Gailloud C (1986) Ophthalmia nodosa and the oculoglandular syndrome of Parinaud. Br J Ophthalmol 70:536–542

    Article  PubMed Central  CAS  PubMed  Google Scholar 

  5. Charbel Issa P, Eis-Hübinger AM, Klatt K, Holz FG, Loeffler KU (2008) Oculoglandular syndrome associated with reactivated Epstein-Barr-virus infection. Br J Ophthalmol 92:740, 855

  6. Parentin F, Molin GD, D’Agaro P, Busetti M, Campello C (2007) Parinaud’s oculoglandular syndrome due to herpes simplex virus type 1. Ocul Immunol Inflamm 15:139–141

    Article  PubMed  Google Scholar 

  7. Pinna A, Sotgiu M, Carta F, Zanetti S, Fadda G (1997) Oculoglandular syndrome in Mediterranean spotted fever acquired through the eye. Br J Ophthalmol 81:172

    Article  CAS  PubMed  Google Scholar 

  8. Espejo E, Bella F, Espaulella J, Romanillos T (1988) Mediterranean spotted fever presenting as oculoglandular syndrome. Trans R Soc Trop Med Hyg 82:642

    Article  CAS  PubMed  Google Scholar 

  9. Khairallah M, Ladjimi A, Chakroun M, Messaoud R, Yahia SB, Zaouali S, Romdhane FB, Bouzouaia N (2004) Posterior segment manifestations of Rickettsia conorii infection. Ophthalmology 111:529–534

    Article  PubMed  Google Scholar 

  10. Agahan AL, Torres J, Fuentes-Páez G, Martínez-Osorio H, Orduña A, Calonge M (2011) Intraocular inflammation as the main manifestation of Rickettsia conorii infection. Clin Ophthalmol 5:1401–1407

    Article  PubMed Central  CAS  PubMed  Google Scholar 

  11. Khairallah M, Ben Yahia S, Toumi A, Jelliti B, Loussaief C, Romdhane FB, Messaoud R, Chakroun M (2009) Ocular manifestations associated with murine typhus. Br J Ophthalmol 93:938–942

  12. Centers for Disease Control and Prevention (2014) CDC Health Information for International Travel 2014. Oxford University Press, New York 2014. Available at: http://www.nc.cdc.gov/travel/yellowbook/2014/chapter-3-infectious-diseases-related-to-travel/rickettsial-spotted-and-typhus-fevers-and-related-infections-anaplasmosis-and-ehrlichiosis

  13. Pinna A (2009) Ocular manifestations of rickettsiosis: 1. Mediterranean spotted fever: laboratory analysis and case reports. Int J Med Sci 6:126–127

    Article  PubMed Central  PubMed  Google Scholar 

  14. Shukla K, Fergie J (2014) Murine typhus associated with Parinaud’s oculoglandular syndrome in 2 children. Pediatr Infect Dis J 33:1195–1196

    Article  PubMed  Google Scholar 

Download references

Acknowledgments

This work has been supported by the Ministry of Higher Education and Research of Tunisia.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Moncef Khairallah.

Ethics declarations

Conflict of interest

The authors report no conflicts of interest.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Abroug, N., Khairallah-Ksiaa, I., Kahloun, R. et al. Parinaud’s oculoglandular syndrome revealing subclinical Rickettsia conorii infection. Int Ophthalmol 35, 717–719 (2015). https://doi.org/10.1007/s10792-015-0094-2

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10792-015-0094-2

Keywords

Navigation