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Unilateral persistent fetal vasculature coexisting with anterior segment dysgenesis

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Persistent fetal vasculature (PFV) is a common congenital developmental anomaly of the eye which results from failure of the embryological primary vitreous and hyaloid vasculature to regress by the time of birth (Int Ophthalmol Clin 48: 53–62, 2008). Typically, it is divided into anterior, posterior or combined types and is characterized by the presence of a vascular stalk located between the optic disc and the posterior lens capsule (Int Ophthalmol Clin 48: 53–62, 2008). Although it has been reported to manifest itself differently, in our case it presented in a microphthalmic eye as anterior segment dysgenesis with broad-based mid-peripheral synechiae, posterior embryotoxon, iridoschisis, ectropion uveae, hypotony and subluxated cataractous lens with a taut anterior hyaloid face which are rare associations with PFV.

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The authors have no financial or proprietary interest in a product, method, or material described herein.

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Correspondence to Shikha Gupta.

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Khokhar, S., Gupta, S., Arora, T. et al. Unilateral persistent fetal vasculature coexisting with anterior segment dysgenesis. Int Ophthalmol 33, 399–401 (2013).

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