Abstract
To determine if primary selective laser trabeculoplasty (SLT) can be repeated with clinical benefit in patients with primary open-angle glaucoma (POAG). Forty-two eyes of 42 patients with POAG were studied. All patients underwent primary SLT treatment of 40–50 shots to the trabecular meshwork over 360°. The treatment response at the initial post-SLT visit (4 weeks), and second post-SLT visit (mean 4 months), clinical success and duration of clinical success were measured. SLT was repeated in all patients after failure to maintain target intraocular pressure (IOP). The same parameters were measured after repeat SLT. The main outcome measures were success of treatment (as defined by reduction of IOP by at least 20 % and below an individually determined target pressure), duration of treatment success and reduction in IOP. No significant difference between initial and repeat treatments was found for mean reduction in IOP or success rate, or duration of success. Survival analysis found significantly longer benefit for repeat treatment compared to initial treatment (P < 0.01). Repeat SLT treatment in eyes with POAG has similar efficacy to primary SLT treatment with respect to reduction in IOP and success rates, produces a longer duration of treatment success.
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References
American Academy of Ophthalmology (2009) Glaucoma. Singapore: American Academy of Ophthalmology p 3–16 and 85–121
Cvenkel B (2004) One-year follow-up of selective laser trabeculoplasty in open-angle glaucoma. Ophthalmologica 218:14–19
Damji KF, Shah KC, Rock WJ, Bains HS, Hodge WG (1999) Selective laser trabeculoplasty v argon laser trabeculoplasty: a prospective randomised clinical trial. Br J Ophthalmol 83(6):718–722
Damji KF, Bovell AM, Hodge WG, Rock W, Shah K, Buhrmann R, Pan YI (2006) Selective laser trabeculoplasty versus argon laser trabeculoplasty: results from a 1-year randomised clinical trial. Br J Ophthalmol 90:1490–1494
Francis BA, Ianchulev T, Schofield JK, Minckler DS (2005) Selective laser trabeculoplasty as a replacement for medical therapy in open-angle glaucoma. Am J Ophthalmol 140(3):524–525
Juzych MS, Chopra MR, Hughes BA, Kim C, Goulas MT, Shin DH (2004) Comparison of long-term outcomes of selective laser trabeculoplasty versus argon laser trabeculoplasty in open-angle glaucoma. Ophthalmology 111(10):1853–1859
Nagar M, Ogunyomade A, O’Brart D, Howes F, Marshall J (2005) A randomised, prospective study comparing selective laser trabeculoplasty with latanoprost for the control of intraocular pressure in ocular hypertension and open angle glaucoma. Br J Ophthalmol 89(11):1413–1417
Nagar M, Luhishi E, Shah N (2009) Intraocular pressure control and fluctuation: the effect of treatment with selective laser trabeculoplasty. Br J Ophthalmol 93:497–501
Lee R, Hitnik C (2006) Projected cost comparison of selective laser trabeculoplasty versus glaucoma medication in the Ontario health insurance plan. Can J Ophthalmol 41(4):449–456
Werner M, Fran Smith M, Doyle W (2007) Selective laser trabeculoplasty in phakic and pseudophakic eyes. Ophthalmic Surg Lasers imaging 38(3):182–188
Moubayed S, Hamid M, Choremis J, Li G (2009) An unusual finding of corneal edema complicating selective laser trabeculoplasty. Can J Ophthalmol 44(3):337–338
Kim D, Singh A (2008) Severe iritis and choroidal effusion following selective laser trabeculoplasty. Ophthalmic Surg Lasers imaging 39(5):409–411
Hong B, Winer J, Martone J, Wand M, Altman B, Shields B (2009) Repeat selective laser trabeculoplasty. J Glaucoma 18(3):180–183
Nagar M, Ogunyomade A, O’Brart DPS, Howes F, Marshall J (2009) A randomised, prospective study comparing selective laser trabeculoplasty with latanoprost for the control of intraocular pressure in ocular hypertension and open angle glaucoma. Br J Ophthalmol 89:1413–1417
Olthoff C, Schouten J, Van de Borne B, Webbers C (2005) Non compliance with ocular hypotensive treatment in patients with glaucoma or ocular hypertension. Ophthalmology 112:953–961
Pham H, Mansberger S, Brandt JD (2008) Argon laser trabeculoplasty. The gold standard. Surv Ophthalmol 53(6):641–646
Shihadeh WA, Ritch R, Liebmann JM (2006) Hyphema occuring during selective laser trabeculoplasty. Ophthalmic Surg Lasers imaging 37(5):432–433
Hodapp E, Parrish I, Anderson D et al (1993) Clinical decision in glaucoma. CV Mosby, St Louis MO, pp 52–61
Melamed S, Ben Simon G, Levkovitch-Verbin H (2003) Selective laser trabeculoplasty as primary treatment for open-angle glaucoma (a prospective, nonrandomized pilot study). Arch Ophthalmol 121(7):957–960
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Avery, N., Ang, G.S., Nicholas, S. et al. Repeatability of primary selective laser trabeculoplasty in patients with primary open-angle glaucoma. Int Ophthalmol 33, 501–506 (2013). https://doi.org/10.1007/s10792-013-9729-3
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DOI: https://doi.org/10.1007/s10792-013-9729-3