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The relationship between optical coherence tomography patterns, angiographic parameters and visual acuity in age-related macular degeneration

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Abstract

To assess the relationships between visual acuity (VA), fluorescein angiographic parameters and optical coherence tomography (OCT) patterns in exudative age-related macular degeneration (AMD). Fifty eyes with confirmed diagnosis of new exudative AMD who underwent fluorescein angiography (FA) and OCT evaluation were reviewed retrospectively. The greatest linear diameter of lesion (GLD) by FA and central foveal thickness (CFT) by OCT were measured. The OCT scans were evaluated for the presence of diffuse retinal thickening (D), cystic spaces (C), subretinal fluid (S) and pigment epithelial detachment (P) and five OCT patterns were detected (D + S; C; C + S; P + C + S; P + D + S). Angiographic classification of choroidal neovascularizations was performed. Correlations were statistically significant for VA and CFT in all patients whereas VA and GLD correlation was statistically significant only in predominantly classic and minimal classic lesions. The lowest VA values were detected in patients with COCT pattern and/or predominantly classic lesion type by FA. The OCT and FA findings when evaluated simultaneously may provide information regarding visual function in AMD.

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Conflict of interest

The authors have no proprietary or commercial interest in any materials discussed in this article.

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Authors and Affiliations

  1. Department of Ophthalmology, Istanbul Goztepe Educational Hospital, Istanbul, Turkey

    Sevil Ari Yaylali, Aylin Ardagil Akcakaya, Hasan Hasbi Erbil, Bahadir Candemir, Cem Mesci & Huseyin Acar

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  1. Sevil Ari Yaylali
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  2. Aylin Ardagil Akcakaya
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  3. Hasan Hasbi Erbil
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  4. Bahadir Candemir
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  5. Cem Mesci
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  6. Huseyin Acar
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Correspondence to Sevil Ari Yaylali.

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Yaylali, S.A., Akcakaya, A.A., Erbil, H.H. et al. The relationship between optical coherence tomography patterns, angiographic parameters and visual acuity in age-related macular degeneration. Int Ophthalmol 32, 25–30 (2012). https://doi.org/10.1007/s10792-012-9519-3

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  • DOI: https://doi.org/10.1007/s10792-012-9519-3

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