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Ruthenium-106 brachytherapy and intravitreal bevacizumab for retinal capillary hemangioma

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Abstract

The purpose of this study is to report a case of retinal capillary hemangioma treated with ruthenium-106 brachytherapy combined with intravitreal bevacizumab. A 58-year-old woman presented with blurred vision in her left eye for 15 days. Best-corrected visual acuity (BCVA) was counting fingers at 3 m in her left eye. Examination showed a peripheral endophytic retinal capillary hemangioma, with associated macular edema and diffuse hard exudates in a macular star pattern. B-scan ultrasonography revealed a solid, highly reflective retinal tumor measuring 7.1 × 7.5 mm in basal dimension and 3.5 mm in thickness. The hemangioma and macular edema were treated with ruthenium-106 brachytherapy (500 Gy) followed 1 month later with an intravitreal injection of 1.25 mg (0.05 ml) bevacizumab. After 10 months of follow-up, examination demonstrated involution of the hemangioma, resolution of the macular edema, less hard exudates, and improvement of BCVA to 20/25. Ruthenium-106 brachytherapy combined with intravitreal bevacizumab was associated with significant involution of the choroidal hemangioma with resolution of the macular edema and improvement in visual acuity.

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Authors and Affiliations

  1. Institute of Ophthalmology, University of Foggia, viale Luigi Pinto, 71100, Foggia, Italy

    Vincenzo Russo, Andrea Stella, Antonio Barone & Nicola Delle Noci

  2. Departments of Ophthalmology and Public Health Sciences, Penn State College of Medicine, Hershey, PA, USA

    Ingrid U. Scott

Authors
  1. Vincenzo Russo
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  2. Andrea Stella
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  3. Antonio Barone
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  4. Ingrid U. Scott
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  5. Nicola Delle Noci
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Correspondence to Antonio Barone.

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Russo, V., Stella, A., Barone, A. et al. Ruthenium-106 brachytherapy and intravitreal bevacizumab for retinal capillary hemangioma. Int Ophthalmol 32, 71–75 (2012). https://doi.org/10.1007/s10792-011-9513-1

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  • DOI: https://doi.org/10.1007/s10792-011-9513-1

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