Abstract
The aim of this study was to analyze macular function by measuring the sensitivity of the macula with fundus-related microperimetry and to compare the results with the best corrected visual acuity (BCVA) and foveal retinal thickness measured by optical coherence tomography (OCT) in patients with idiopathic epimacular membrane. We prospectively reviewed 66 eyes with idiopathic epimacular membrane and 35 normal healthy eyes in patients who had undergone fundus-related microperimetry and OCT. The macular sensitivity was measured using the recently introduced fundus-related microperimeter, MP-1. The mean retinal sensitivities in the central 10° (central microperimetry, cMP-1) and in the paracentral 10–20° (paracentral microperimetry, pMP-1) areas were determined and correlated with the BCVA and OCT-measured foveal thickness. Eyes with epimacular membranes showed significantly lower log MAR BCVA (P < 0.001) and cMP-1 microperimetry sensitivity (P < 0.001) and significantly higher OCT foveal thickness (P < 0.001) than control eyes. There was a significant correlation between the BCVA and mean retinal sensitivity in the cMP-1 (r 2 = 0.26, P < 0.001) and the pMP-1 (r 2 = 0.07, P = 0.008) areas. A significant negative correlation was observed between the foveal thickness and the mean retinal sensitivity in the cMP-1 (r 2 = 0.13, P < 0.001) area. Retinal sensitivity in the central macular area determined by MP-1 microperimetry was significantly correlated with BCVA and with foveal thickness. The combination of OCT and microperimetry may help a better evaluation of the patients with idiopathic epimacular membrane.
Similar content being viewed by others
References
Hirokawa H, Jalkh AE, Takahashi M et al (1988) Role of the vitreous in idiopathic preretinal macular fibrosis. Am J Ophthalmol 106:536–545
Appiah AP, Hirose T, Kado M (1988) A review of 324 cases of idiopathic premacular gliosis. Am J Ophthalmol 106:533–535
McDonald HR, Johnson RN, Ai E et al (2001) Macular epiretinal membranes. In: Ryan SJ (ed) Retina, vol 3, 3rd edn. Mosby, St. Louis, pp 2531–2546
Willins JR, Puliafito CA, Hee MR et al (1996) Characterization of epiretinal membranes using OCT. Ophthalmology 103:2142–2151
Tanikawa A, Horiguchi M, Kondo M et al (1999) Abnormal focal macular electroretinograms in eyes with idiopathic epimacular membrane. Am J Ophthalmol 127:559–564
Niwa T, Terasaki H, Kondo M et al (2003) Function and morphology of macula before and after removal of idiopathic epiretinal membrane. Investig Ophthalmol Vis Sci 44:1652–1656
Moschos M, Apostolopoulos M, Ladas J et al (2001) Assessment of macular function by multifocal electroretinogram before and after epimacular membrane surgery. Retina 21:590–595
Ozdemir H, Karacorlu SA, Senturk F et al (2008) Assessment of macular function by microperimetry in unilateral resolved central serous chorioretinopathy. Eye 22:204–208
Polinar LS, Olk RJ, Grand MG et al (1988) Surgical management of premacular fibroplasia. Arch Ophthalmol 106:761–764
Marguerio RP, Cox MS, Trese MT et al (1985) Removal of epimacular membranes. Ophthalmology 92:1075–1083
Parks S, Keating D, Williamson TH et al (1996) Functional imaging of the retina using the multifocal electroretinogram: a control study. Br J Ophthalmol 80:831–834
Sutter EE, Tran D (1992) The field topography of ERG in man. 1. The photopic luminance response. Vis Res 32:433–466
Watanabe A, Arimoto S, Nishi O (2009) Correlation between metamorphopsia and epiretinal membrane optical coherence tomography findings. Ophthalmology 116:1788–1793
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Karacorlu, M., Ozdemir, H., Senturk, F. et al. Correlation of retinal sensitivity with visual acuity and macular thickness in eyes with idiopathic epimacular membrane. Int Ophthalmol 30, 285–290 (2010). https://doi.org/10.1007/s10792-009-9333-8
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s10792-009-9333-8