Abstract
We report a case of unilateral acute idiopathic maculopathy (UAIM) with new clinical findings. A 34-year-old Japanese man had a neurosensory retinal detachment (~5 disk diameters) with yellowish-white exudates at the macula in the left eye (visual acuity (VA) 0.4). Fluorescein angiography (FA) showed early hypofluorescent spots and late pooling in the subretinal space. Three weeks after onset, indocyanine green angiography (IA) showed numerous hypofluorescent spots at the lesion. Optical coherence tomography (OCT) showed subretinal fluids and an elevated choroidal lesion with low reflectivity, suggesting choroidal edema. The VA and fundus appearance spontaneously resolved without treatment three months after onset. The VA was 1.0 six months after onset. Irregular pigmentation remained at the macular lesion. The main UAIM pathology may be outer retinal layer and retinal pigment epithelial inflammation. FA, IA, and OCT suggested that choroidal inflammation may be involved in the pathogenesis of UAIM.
References
Yannuzzi LA, Jampol LM, Rabb MF et al (1991) Unilateral acute idiopathic maculopathy. Arch Ophthalmol 109:1411–1416
Freund KB, Yannuzzi LA, Barile GR et al (1996) The expanding clinical spectrum of unilateral acute idiopathic maculopathy. Arch Ophthalmol 114:555–559
Beck AP, Jampol LM, Glasser DA et al (2004) Is coxsackievirus the cause of unilateral acute idiopathic maculopathy? Arch Ophthalmol 122:121–123
Gelisken F, Schneider U, Inhoffen W et al (1998) Unilateral acute idiopathic maculopathy: an unusual presentation? Retina 18:477–479
Nakazawa T, Yamaguchi T, Tamai M et al (2003) Clinical features of bilateral acute idiopathic maculopathy. Jpn J Ophthalmol 47:385–391
Akduman L, Feiner M, Kaplan H et al (1999) Progressive changes in the fluorescein and indocyanine green angiogram in acute idiopathic maculopathy. Ocul Immunol Inflamm 7:97–102
Freund KB, Yannuzzi LA (1997) Vogt–Koyanagi–Harada syndrome. In: Yannuzzi LA, Flower RW, Slakter JS (eds) Indocyanine green angiography. CV Mosby, St. Louis, pp 260–269
Oshima Y, Harino S, Tano Y et al (1996) Indocyanine green angiographic findings in Vogt–Koyanagi–Harada disease. Am J Ophthalmol 122:58–66
Aggio FB, Farah ME, Souza EC et al (2006) STRATUSOCT and multifocal ERG in unilateral acute idiopathic maculopathy. Graefes Arch Clin Exp Ophthalmol 244:510–556
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Haruta, H., Sawa, M., Saishin, Y. et al. Clinical findings in unilateral acute idiopathic maculopathy. Int Ophthalmol 30, 199–202 (2010). https://doi.org/10.1007/s10792-009-9299-6
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DOI: https://doi.org/10.1007/s10792-009-9299-6