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Unusual temperature dependencies of Mössbauer parameters of the nanosized iron cores in ferritin and its pharmaceutical analogues

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Abstract

Human liver ferritin and its pharmaceutical analogues, namely, Maltofer®, Ferrum Lek and Ferrifol®, were examined using temperature variable Mössbauer spectroscopy. The best fits of measured spectra at 295–90 K were performed using 5 quadrupole doublets with equal line widths. Obtained components were associated with various layers and/or regions of nanosized iron cores with different size and packing arrangement. Unusual temperature dependencies of line widths, normalized total and relative areas, isomer shifts and quadrupole splittings were observed and related to the low temperature structural rearrangements in different layers/regions of the iron cores in ferritin and its analogues.

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Acknowledgements

M.I.O. and I.V.A. were supported by the Ministry of Science and Higher Education of the Russian Federation (the Project № FEUZ-2020-0060). This work was carried out within the Agreement of Cooperation between the Ural Federal University (Ekaterinburg) and the Eötvös Loránd University (Budapest).

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Authors and Affiliations

  1. Institute of Physics and Technology, Ural Federal University, Ekaterinburg, 620002, Russian Federation

    I.V. Alenkina & M.I. Oshtrakh

  2. Laboratory of Nuclear Chemistry, Institute of Chemistry, Eötvös Loránd University, Budapest, Hungary

    E. Kuzmann

  3. Racah Institute of Physics, The Hebrew University, 91904, Jerusalem, Israel

    I. Felner

  4. Centre for Energy Research, Konkoly-Thege Miklós út. 29-33, Budapest, 1121, Hungary

    V. Kovacs Kis

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  1. I.V. Alenkina
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  2. E. Kuzmann
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  3. I. Felner
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  4. V. Kovacs Kis
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  5. M.I. Oshtrakh
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Correspondence to M.I. Oshtrakh.

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This article is part of the Topical Collection on Proceedings of the International Conference on Hyperfine Interactions (HYPERFINE 2021), 5-10 September 2021, Brasov, Romania

Edited by Ovidiu Crisan

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Alenkina, I., Kuzmann, E., Felner, I. et al. Unusual temperature dependencies of Mössbauer parameters of the nanosized iron cores in ferritin and its pharmaceutical analogues. Hyperfine Interact 242, 9 (2021). https://doi.org/10.1007/s10751-021-01737-3

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  • DOI: https://doi.org/10.1007/s10751-021-01737-3

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