Traditional Uses of Medicinal Plants in Artuklu, Turkey

Abstract

We conducted an ethnobotanical field study of traditional medicinal plants in 91 villages of Artuklu District among four ethnic groups: Turkish, Kurdish, Arabic, and Assyrian. We interviewed 365 elderly informants and recorded traditional uses of 85 identified botanical taxa, including four endemic species previously unidentified as medicinal plants: Arum rupicola Boiss., Gundelia mesopotamica Fırat, Alkanna trichophila Hub.-Mor., and Crocus leichtlinii (Dewar) Bowles. We gathered data specifically on medicinal uses of these taxa to determine the relative importance of the species surveyed and calculate the informant consensus factor (FIC) in relation to medicinal plant use. The highest use values were recorded for the species Teucrium polium L. (0.78), Urtica dioica L. (0.60) and Crataegus azarolus L., (0.59), while the highest FIC was for gynecological diseases (0.93).

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References

  1. Abu-Irmaileh, B. E., and Afifi, F. U. (2003). Herbal Medicine in Jordan with Special Emphasis on Commonly Used Herbs. Journal of Ethnopharmacology 89: 193-197.

    Article  Google Scholar 

  2. Akan, H., Korkut, M. M., and Balos, M. M. (2008). An Ethnobotanical Study Around Arat Mountain and its surroundings (Birecik, Şanlıurfa). Science and Eng. J of Fırat Univ. 20(1): 67-81.

    Google Scholar 

  3. Akerele, O. (1988). Medical Plants and Primary Health Care: An Agenda for Action. Fitoterapia 59: 355-363. https://doi.org/10.1016/j.sbspro.2011.05.195.

    Article  Google Scholar 

  4. Akgül, A. (2008). Ethnobotany at Midyat (Mardin). Msc, Van Yüzüncü Yıl University, Van, pp. 176.

    Google Scholar 

  5. Akgul, A., Akgul, A., Senol, S. G., Yildirim, H. and Dogan, Y. (2018). An ethnobotanical study in Midyat (Turkey), a city on the silk road where cultures meet. Journal of Ethnobiology and Ethnomedicine 14: 12. https://doi.org/10.1186/s13002-017-0201-8.

    Article  Google Scholar 

  6. Akyol, Y., and Altan, Y. (2013). Ethnobotanical studies in the Maldan Village (Province Manisa, Turkey). Marmara Pharmaceutical Journal 17: 21-25.

    Article  Google Scholar 

  7. Al-Bayati, F. A., and Al-Mola, H. F. (2008). Antibacterial and antifungal activities of different parts of Tribulus terrestris L. growing in Iraq. Journal of Zhejiang University: Science B 9(2): 154-159.

    Article  Google Scholar 

  8. Al-Marzoqi, A. H., Al-Khafaji, N. M. S., and Hussein, H. J. (2016). In vitro Antibacterial Activity Assessment of the crude Phenolic, Alkaloid and Terpenoid compounds extracts of Lepidium sativum L. on Human Pathogenic Bacteria. International Journal of Chem. Tech. Research 9(4): 529-532.

    Google Scholar 

  9. Al-Qura’n, S. (2009). Ethnopharmacological Survey of Wild Medicinal Plants in Showbak, Jordan. Journal of Ethnopharmacology 123: 45-50. https://doi.org/10.1016/j.jep.2009.02.03.

    Article  Google Scholar 

  10. Altundağ Çakır, E. (2017). Traditional knowledge of wild edible plants of Iğdır Province (East Anatolia, Turkey). Acta Soc. Bot. Pol. 86(4): 35-68. https://doi.org/10.5586/asbp.3568.

    Article  Google Scholar 

  11. Arasan, Ş. (2014). Plants Used In Folkloric Medicine In Savur (Mardin) Area And Their Application Areas. Msc, Van Yüzüncü Yıl University, Van, pp. 303.

    Google Scholar 

  12. Asgary, S., Naderi, G. H., Sarrafzadegan, N., Mohammadifard, N., Mostafavi, S., and Vakili, R. (2000). Antihypertensive and antihyperlipidemic effects of Achillea wilhelmsii. Drugs Under Experimental and Clinical Research 26: 89-93.

    Google Scholar 

  13. Bano, A., Ahmad, M., Ben Hadda, T., Saboor, A., Sultana, S., Zafar, M., Khan, M. P., Arshad, M., and Ashraf, M. A. (2014). Quantitative ethnomedicinal study of plants used in the skardu valley at high altitude of Karakarom–Himalayan range, Pakistan. J. Ethnobiol. Ethnomed. 10(43): 1-17. https://doi.org/10.1186/1746-4269-10-43.

    Article  Google Scholar 

  14. Barış, D., Kızıl, M., Aytekin, Ç., Kızıl, G., Yavuz, M., Çeken, B., and Ertekin, A. S. (2011). In Vitro Antimicrobial and Antioxidant Activity of Ethanol Extract of Three Hypericum and Three Achillea Species From Turkey. International Journal of Food Properties 14(2): 339-355. https://doi.org/10.1080/10942910903189256.

    Article  Google Scholar 

  15. Baytop, T. (1999). Therapy with Medicinal Plants in Turkey (Past and Present). (2nd ed.), Nobel Medicine Publication, Istanbul, pp. 118-119.

  16. Boussoualim, N., Trabsa, H., Krache, I., Arrar, L., and Baghiani, A. (2014). Anti-bacterial and β- Lactamase inhibitory effects of Anchusa azurea and Globularia alypum extracts. Research Journal of Pharmaceutical, Biological and Chemical Sciences 5 (1), 742-749.

    Google Scholar 

  17. Cakilcioglu, U., and Turkoglu, I. (2010). An ethnobotanical survey of medicinal plants in Sivrice (Elazığ-Turkey). Journal of Ethnopharmacology 132(1): 165-175. https://doi.org/10.1016/j.jep.2010.08.017.

    Article  Google Scholar 

  18. Cakilcioglu, U., Khatun, S., Turkoglu, I., and Hayta, S. (2011). Ethnopharmacological survey of Medicinal plants in Maden (Elazig-Turkey). Journal of Ethnopharmacology 137: 469-486. doi:https://doi.org/10.1016/j.jep.2011.05.046.

    Article  Google Scholar 

  19. Calixto, J. B. (2005). Twenty-five years of research on medicinal plants in Latin America: a personal view. Journal of Ethnopharmacology 100(1-2): 131-134. https://doi.org/10.1016/j.jep.2005.06.004.

    Article  Google Scholar 

  20. Conforti, F., Marcotullio, M. C., Menichini, F., Statti, G. A., Vannutelli, L., Burini, G., Menichini, F., and Curini, M. (2011). The Influence of Collection Zone on Glucosinolates, Polyphenols and Flavonoids Contents and Biological Profiles of Capparis sicula ssp. sicula. Food Sci. Technol. Int. 17(2): 87-97. https://doi.org/10.1177/1082013210368583.

    Article  Google Scholar 

  21. Conforti, F., Menichini, F., Formisano, C., Rigano, D., Senatore, F., Bruno, M., Rosselli, S., and Çelik, S. (2012). Anthemis wiedemanniana essential oil prevents LPS-induced production of NO in RAW 264.7 macrophages and exerts antiproliferative and antibacterial activity. Nat. Prod. Res. 26: 1594-1601. doi:https://doi.org/10.1080/14786419.2011.585988.

    Article  Google Scholar 

  22. Çakılcıoğlu, U., Türkoğlu, H., and Kürşat, M. (2007). Ethnobotanical Features Of Harput (Elazıg) And Its Vicinity. Research Of Eastern Anatolia Region 5(2): 22-28.

    Google Scholar 

  23. Dalar, A., Türker, M., and Konczak, I. (2012). Antioxidant capacity and phenolic constituents of Malva neglecta Wallr. and Plantago lanceolata L. from Eastern Anatolia Region of Turkey. Journal of Herbal Medicine 2: 42-51. https://doi.org/10.1016/j.hermed.2012.03.001.

    Article  Google Scholar 

  24. Davis, P. H. 1965 &, 1985. Flora of Turkey and the East Aegean Islands. Edinburgh University Press, Edinburgh, England, Vol.1-9.

  25. Deniz, L., Serteser, A., and Kargıoğlu, M. (2010). Local Names and Ethnobotanical Features of Some Plants in Usak University (Usak) and Its Near Vicinity. AKU-J. Sci. Eng. 01: 57-72.

    Google Scholar 

  26. Doğan, G., and Bağcı, E. (2011). The Plants Benefit to Public in Some Residential Area of Elazığ Using Traditional Ecological Knowledge and Their Etnobotanical Features. Fırat Univ. Journal of Science 23(2): 77-86.

    Google Scholar 

  27. Doğan, A. (2014). Ethnobotanical Investigations in Pertek (Tunceli). Phd, Marmara University, İstanbul, pp. 459.

    Google Scholar 

  28. Ekim, T., Koyuncu, M., Vural, M., Duman, H., Aytaç, Z., and Adıgüzel, N. (2000). Red Data Book Of Turkish Plants (Pteridophyta and Spermatophyta). Turkish Association For The Conservation Of Nature, Van Centennial University. Barışcan Ofset. Ankara.

    Google Scholar 

  29. Ertuğ, F. (2004). Wild edible plants of the Bodrum area (Muğla, Turkey). Turkish Journal of Botany 28: 161-174.

    Google Scholar 

  30. Gençay, A. (2007). Etnobotanical Aspects Of Cizre (Şırnak). Msc, Van Yüzüncü Yıl University, Van, pp. 267.

    Google Scholar 

  31. Gupta, S., Gupta, P., and Patsariya, S. (2012). Phytochemical and Pharmacological review on Fenugreek (Trigonella foenum-graecum). Current Research in Pharmaceutical Sciences 01: 11-13.

    Google Scholar 

  32. Güner, A., Aslan, S., Ekim, T., Vural, M., and Babaç, M. T., (eds.). (2012). Türkiye Bitkileri Listesi (Damarlı Bitkiler). Nezahat Gökyiğit Botanik Bahçesi ve Flora Araştırmaları Derneği Yayını. İstanbul, Turkey. ISBN: 978- 605-60425-7-7.

  33. Gürbüz, I., Özkan, A. M., Yeşilada, E., and Kutsal, O. (2005). Anti-ulcerogenic activity of some plants used in folk medicine of Pinarbasi (Kayseri, Turkey). Journal of Ethnopharmacology 101: 313-318. doi:https://doi.org/10.1016/j.jep.2005.05.015.

    Article  Google Scholar 

  34. Haşimi, N., Ertaş, A., Oral, E. V., Alkan, H., Boğa, M., Yılmaz, M. A., Yener, İ., Gazioğlu, I., Özaslan, C., Akdeniz, M., and Kolak, U. (2017). Chemical Profile of Malva neglecta and Malvella sherardiana by LcMS/MS, GC/MS and Their Anticholinesterase, Antimicrobial and Antioxidant Properties With Aflatoxin Contents. Marmara Pharmaceutical Journal 21(3): 471-484. https://doi.org/10.12991/mpj.31235.

    Article  Google Scholar 

  35. Hayta, S., Polat, R., and Selvi, S. (2014). Traditional uses of medicinal plants in Elazığ (Turkey). Journal of Ethnopharmacology 154: 613-623.

    Article  Google Scholar 

  36. Heinrich, M. (2000). Ethnobotany and its role in drug development. Phytotherapy Research 14(7): 479-488. https://doi.org/10.1002/1099-1573(200011)14:7<479::AID-PTR958>3.0.CO;2-2.

    Article  Google Scholar 

  37. Kargıoğlu, M., Cenkci, S., Serteser, A., Evliyaoğlu, N., Konuk, M., Kök, M. Ş., Bağcı, Y. (2008). An ethnobotanical survey of inner-West Anatolia, Turkey. Human Ecology 36: 763-777.

    Article  Google Scholar 

  38. Kargıoğlu, M., Cenkci, S., Serteser, A., Konuk, M., and Vural, G. (2010). Traditional Uses of Wild Plants in the Middle Aegean Region of Turkey. Human Ecology 38: 429-450. doi:https://doi.org/10.1007/s10745-010-9318-2.

    Article  Google Scholar 

  39. Kaval, İ., Behçet, L., and Çakılcıoğlu, U. (2014). Ethnobotanical study on medicinal plants in Geçitli and its surrounding (Hakkari-Turkey). Journal of Ethnopharmacology 155: 171-184. https://doi.org/10.1016/j.jep.2014.05.014.

    Article  Google Scholar 

  40. Kaya, G. (2006). Discussion of P&P model used for estimating option value of forest ecosystems as medicinal plant resources. Journal of the Bartın Faculty of Forestry 8: 23-32.

    Google Scholar 

  41. Kaya, A., Demirci, B., Doğuc, S., and Dinç, M. (2017). Composition of the essential oil of Stachys sericantha, S. gaziantepensis, and S. mardinensis (Lamiaceae) from Turkey. International Journal of Food Properties 20(11): 2639-2644. https://doi.org/10.1080/10942912.2016.1247100.

    Article  Google Scholar 

  42. Kaya, Ö. F., Dağlı, M., and Çelik, H. T. (2020). An ethnobotanical research in Şanlıurfa central district and attached Villages (Turkey). Indian Journal of Traditional Knowledge 19(1): 7-23.

    Google Scholar 

  43. Keser, S., Celik, S., and Turkoglu, S. (2013). Total phenolic contents and free-radical scavenging activities of grape (Vitis vinifera L.) and grape products. International Journal of Food Sciences and Nutrition 64(2): 210-216. https://doi.org/10.3109/09637486.2012.728199.

    Article  Google Scholar 

  44. Kivcak, B., Mert, T., Sağlam, H., Öztürk, T., Kürkçüoğlu, M., and Başer, K. H. C. (2007). Chemical Composition and Antimicrobial Activity of The Essential Oil of Anthemis wiedemanniana from Turkey. Chemistry of Natural Compounds 43(1): 47-51. https://doi.org/10.1007/s10600-007-0029-x.

    Article  Google Scholar 

  45. Kloutusos, G., Balatsouras, D. G., Kaberos, A. C., Kandiloros, D., Ferekidis, E., and Economou, C. (2001). Upper airway edema resulting from use of Ecballium elaterium. The Laryngoscope 111(9): 1652-1655. https://doi.org/10.1097/00005537-200109000-00030.

    Article  Google Scholar 

  46. Malyer, H., Özaydın, S., Tümen, G., and Er, S. (2004). Ethnobotanics characteristics of plants sold in herbalist in Tekirdag and its surroundings. Dumlupınar University Journal of Science 7: 103-111.

    Google Scholar 

  47. Mesfin, F., Demissew, S., and Teklehaymanot, T. (2009). An ethnobotanical study of medicinal plants in Wonago Woreda, SNNPR, Ethiopia. Journal of Ethnobiology and Ethnomedicine 5: 28. https://doi.org/10.1186/1746-4269-5-28.

    Article  Google Scholar 

  48. Muthu, C., Ayyanar, M., Raja, N., and Ignacimuthu, S. (2006). Medicinal plants used by traditional healers in Kancheepuram district of Tamil Nadu, India. Journal of Ethnobiology and Ethnomedicine 2: 43.

    Article  Google Scholar 

  49. Nadiroğlu, M., Behçet, L., and Çakılcıoğlu, U. (2019). An ethnobotanical survey of medicinal plants in Karlıova (Bingöl-Turkey). Indian J. of Traditional Knowledge 18(1): 76-87.

    Google Scholar 

  50. Özüdoğru, B., Akaydın, G., Erik, S., and Yesilada, E. (2011). Inferences from an ethnobotanical field expedition in the selected locations of Sivas and Yozgat provinces (Turkey). Journal of Ethnopharmacology 137: 85-98. https://doi.org/10.1016/j.jep.2011.04.050.

    Article  Google Scholar 

  51. Pirbalouti, A. G., Reisei, M., Razavi-Zade, R., Hamedi, B., and Alavi-Samani, S. M. (2013). Antioxidant Activity and Total Phenolic of Extracts from Five Species of Amygdalus Leaves. Electronic Journal of Biology 9(4): 92-95.

    Google Scholar 

  52. Polat, R., Satıl, F., and Cakilcioglu, U. (2011). Medicinal plants and their use properties of sold in herbal market in Bingöl district. Biological Diversity and Conservation 4: 25-35.

    Google Scholar 

  53. Polat, R., Cakilcioglu, U., and Satıl, F. (2013). Traditional uses of medicinal plants of Solhan (Bingöl-Turkey). Journal of Ethnopharmacology 48: 951-963.

    Article  Google Scholar 

  54. Rizwana, H., Alwhibi, M. S., and Soliman, D. A. (2016). Antimicrobial Activity and Chemical Composition of Flowers of Matricaria aurea a Native Herb of Saudi Arabia. International Journal of Pharmacology 12(6): 576-586. https://doi.org/10.3923/ijp.2016.576.586.

    Article  Google Scholar 

  55. Saad, A. M., Ghareeb, M. A., Abdel-Aziz, M. S., Madkour, H. M. F., Khalaf, O. M., El-Ziaty, A. K., and Abdel-Mogib, M. (2017). Chemical constituents and biological activities of different solvent extracts of Prosopis farcta growing in Egypt. Journal of Pharmacognosy and Phytotherapy 9(5): 67-76. https://doi.org/10.5897/JPP2017.0452.

    Article  Google Scholar 

  56. Samuelsen, A. B. (2000). The traditional uses, chemical constituents and Biological activities of Plantago major L. A review. Journal of Ethnopharmacology 71: 1-21. https://doi.org/10.1016/S0378-8741(00)00212-9.

    Article  Google Scholar 

  57. Sargin, S. A., Selvi, S., and Büyükcengiz, M. (2015). Ethnomedicinal plants of Aydıncık District of Mersin, Turkey. Journal of Ethnopharmacology 4(174): 200-216. https://doi.org/10.1016/j.jep.2015.08.008.

    Article  Google Scholar 

  58. Satıl, F., Akçiçek, E., and Selvi, S. (2008). An ethnobotanicaly study in Madra Mountain (Balıkesir-İzmir) and vicinity. Research Journal of Biology Sciences 1: 31-36.

    Google Scholar 

  59. Savikin, K., Zdunic, G., Menkovic, N., Zivkovic, J., Cujic, N., Terescenko, M., and Bigovic, D. (2013). Ethnobotanical study on traditional use of medicinal plants in south-western Serbia, Zlatibor district. Journal of Ethnopharmacology 146(3): 803-810.

    Article  Google Scholar 

  60. Schippmann, U., Leaman, D., and Cunnigham, A. B. (2006). Cultivation and wild collection of Medicinal and aromatic plants under sustainability aspects. R.J. Bogers, L.E. Craker, D. Lange (Eds.), Medicinal and Aromatic Plants, Springer, Dordrecht, p. 17 (Wageningen UR Frontis).

  61. Tardio, J., and Pardo-de-Santayana, M. (2008). Cultural importance indicates: a comparative analysis based on the useful wild plants of Southern Cantabria (Northern Spain). Econ. Bot. 62: 24-39.

    Article  Google Scholar 

  62. Teklehaymanot, T., and Giday, M. (2007). Ethnobotanical Study of Medicinal Plants Used by People in Zegie Peninsula, Northwestern Ethiopia. Journal of Ethnobiology and Ethnomedicine 3: 12. 10.1186-4/1746269-3-12.

  63. Tepe, B., Donmez, E., Unlu, M., Candan, F., Daferera, D., Vardar-Unlu, G., Polissiou, G., and Sokmen, A. (2004). Antimicrobial and antioxidative activities of the essential oils and methanol extracts of Salvia cryptantha (Montbret et Aucher ex Benth.) and Salvia multicaulis (Vahl). Food Chemistry 84: 519-525. https://doi.org/10.1016/S0308-8146(03)00267-X.

    Article  Google Scholar 

  64. Tosun, G., Yaylı, B., Arslan, T., Yasar, A., Alpay-Karaoglu, S., and Yaylı, N. (2012). Comparative Essential Oil Analysis of Calendula arvensis L. Extracted by Hydrodistillation and Microwave Distillation and Antimicrobial Activities. Asian Journal of Chemistry 24(5): 1955-1958.

    Google Scholar 

  65. Trotter, R. T., and Logan, M. H. (1986). Informant Consensus: A New Approach for Identifying Potentially Effective méDicinal Plants. In: Etkin, N.L. (Ed.), Plants in Indigenous Medicine and Diet, Behavioural Approaches, Redgrave Publishing Company, Bedfore Hills, New York.

    Google Scholar 

  66. Ugulu, I., Aydin, H., Yorek, N., and Dogan, Y. (2008). The impact of endemism concept on environmental attitudes of secondary school students. Natura Montenegrina 7: 165-173.

    Google Scholar 

  67. Vijayakumar, S., Yabesh, J.E., Prabhu, S., Manikandan, R., and Muralidharan, B. (2015). Quantitative ethnomedicinal study of plants used in the Nelliyampathy hills of Kerela, India. Journal of Ethnopharmacology 161: 238-254.

    Article  Google Scholar 

  68. WHO, 2002. Traditional Medicine Strategy 2002-2005, World Health Organization, Geneva.

    Google Scholar 

  69. Yeşil, Y., Çelik, M., and Yılmaz, B. (2019). Wild edible plants in Yeşilli (Mardin-Turkey), a multicultural area. Journal of Ethnobiology and Ethnomedicine 15: 52. https://doi.org/10.1186/s13002-019-0327-y.

    Article  Google Scholar 

  70. Yıldırım, I., Uğur, Y., and Kutlu, T. (2017). Investigation of Antioxidant Activity and Phytochemical Compositions of Celtis tournefortii. Free Radicals and Antioxidants 7(2): 160-165. https://doi.org/10.5530/fra.2017.2.24.

    Article  Google Scholar 

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Acknowledgments

We are grateful to all the informants who participated in this study and shared their knowledge with us.

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Kılıç, M., Yıldız, K. & Kılıç, F.M. Traditional Uses of Medicinal Plants in Artuklu, Turkey. Hum Ecol (2020). https://doi.org/10.1007/s10745-020-00180-2

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Keywords

  • Medicinal plants
  • Ethnobotany
  • Artuklu
  • Mardin
  • Southeastern Anatolia
  • Turkey