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Soluble ST2: a valuable prognostic marker in heart failure

Abstract

Natriuretic peptides have been at the forefront of biomarker use in heart disease and have been universally recommended as the ideal biomarker in the setting of heart failure. Soluble ST2 is one such biomarker which has found value as a prognostic marker and can be used individually or along with natriuretic peptides in order to prognosticate patients with heart failure. Leading cardiovascular organisations have recognised this biomarker, though its role as a diagnostic marker is yet to be determined. We aim to investigate the role of sST2 in heart failure in the existing literature.

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Contributions

All authors contributed to the study conception and design. Material preparation, data collection and analysis were performed by Sugeevan Savarimuthu, Pavan Goel, and Amer Harky. The first draft of the manuscript was written by Sugeevan Savarimuthu, and all authors commented on previous versions of the manuscript. All authors read and approved the final manuscript. All authors have read and approve of the data being presented in the manuscript.

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Correspondence to Sugeevan Savarimuthu.

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Savarimuthu, S., Goel, P. & Harky, A. Soluble ST2: a valuable prognostic marker in heart failure. Heart Fail Rev (2022). https://doi.org/10.1007/s10741-022-10258-2

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  • DOI: https://doi.org/10.1007/s10741-022-10258-2

Keywords

  • Heart failure
  • Soluble ST2
  • Natriuretic peptide
  • Biomarker