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Ventricular non-compaction review

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Abstract

Left ventricular non-compaction cardiomyopathy (LVNC) is a rare and unclassified cardiomyopathy that carries the potential to cause heart failure, arrhythmias, and embolic events within adults. The diagnosis of this cardiomyopathy can be based off a variety of echocardiographic, cardiac magnetic resonance (CMR), and computed tomography (CT) imaging criteria; none of which have been standardized to establish a firm diagnosis. This is further complicated by the observation from prior studies that LVNC may present as different forms of cardiomyopathy, each with its own subset of nuances that may change treatment strategies. Management of such cardiomyopathy has been debated in terms of anticoagulation, electrophysiologic studies to prevent arrhythmia, as well as heart failure prevention. Not enough data exists in regard to establishing firm guidelines for management. The following article aims to provide a comprehensive review in regard to the etiologies, pathogenesis, diagnostic criteria, management, and treatment of LVNC.

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Shaurya Srivastava—conducted research regarding the findings of each article, wrote the manuscript, reviewed and helped edit the manuscript. Majid Yavari—helped with creation of visuals (tables and figure), reviewed and helped edit manuscript. Abdullah Al Abcha—helped edit and review each section of the article. Sandeep Banga—had the initial idea for this review, helped conduct research regarding each article, helped to edit and review each section. George Abela—cardiology attending, helped review the article.

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Correspondence to Shaurya Srivastava.

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Srivastava, S., Yavari, M., Al-abcha, A. et al. Ventricular non-compaction review. Heart Fail Rev 27, 1063–1076 (2022). https://doi.org/10.1007/s10741-021-10128-3

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