Transcatheter valve interventions in heart failure: new answers to old questions

  • Marijana Tadic
  • Cesare Cuspidi


Heart failure (HF) is often associated with different valve diseases, predominantly functional mitral and tricuspid regurgitation. However, the association between HF and aortic stenosis, particularly low-flow low-gradient aortic stenosis, is not infrequent. Severe mitral and tricuspid regurgitations, as well as aortic stenosis, in HF patients worsen prognosis and left ventricular dilatation and induce further reduction in left ventricular ejection fraction. Transcatheter edge-to-edge mitral and tricuspid valve repair and transcatheter aortic valve implantation could be an important therapeutic option with a satisfactory long-term outcome in HF patients with comorbidities and even in patients with severely depressed ejection fraction.


Heart failure Transcatheter aortic valve interventions MitraClip Mitral annuloplasty Tricuspid annuloplasty 


Author contributions

MT and CC were involved in design and writing the article. MT was involved in drafting and CC in revising critically for important intellectual content.

Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.


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Authors and Affiliations

  1. 1.Department of Internal Medicine and Cardiology, Department of Cardiology, Campus Virchow Klinikum (CVK)Charité – Universitätsmedizin BerlinBerlinGermany
  2. 2.Clinical Research UnitUniversity of Milan-Bicocca and Istituto Auxologico ItalianoMedaItaly

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