Heart Failure Reviews

, Volume 23, Issue 4, pp 507–516 | Cite as

Devices and interventions for the prevention of adverse outcomes of tachycardia on heart failure

  • Jasneet Devgun
  • Yash B. Jobanputra
  • Michael Arustamyan
  • Robert Chait
  • Waqas Ghumman


Heart failure (HF) is the leading cause of hospitalization in the USA. Despite advances in pharmacologic management, the incidence of HF is on the rise and survivability is persistently reduced. Sympathetic overdrive is implicated in the pathophysiology of HF, particularly HF with reduced ejection fraction (HFrEF). Tachycardia can be particularly deleterious and thus has spurred significant investigation to mitigate its effects. Various modalities including vagus nerve stimulation, baroreceptor activation therapy, spinal cord stimulation, renal sympathetic nerve denervation, left cardiac sympathetic denervation, and carotid body removal will be discussed. However, the effects of these modalities on tachycardia and its outcomes in HFrEF have not been well-studied. Further studies to characterize this are necessary in the future.


Heart failure Tachycardia Baroreceptor activation therapy Vagus nerve stimulation Renal sympathetic nerve denervation 


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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2018

Authors and Affiliations

  • Jasneet Devgun
    • 1
  • Yash B. Jobanputra
    • 3
  • Michael Arustamyan
    • 2
  • Robert Chait
    • 4
  • Waqas Ghumman
    • 4
  1. 1.Department of Internal MedicineThe Ohio State University Wexner Medical CenterColumbusUSA
  2. 2.Lake Erie College of Osteopathic MedicineErieUSA
  3. 3.Department of Internal MedicineUniversity of Miami Miller School of Medicine Regional CampusAtlantisUSA
  4. 4.Department of CardiologyUniversity of Miami Miller School of Medicine Regional CampusAtlantisUSA

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