Heart Failure Reviews

, 14:155

OSA: the new cardiovascular disease

Part II: overview of cardiovascular diseases associated with obstructive sleep apnea
  • Kiran Devulapally
  • Raymond PongonisJr.
  • Rami Khayat

DOI: 10.1007/s10741-008-9101-2

Cite this article as:
Devulapally, K., Pongonis, R. & Khayat, R. Heart Fail Rev (2009) 14: 155. doi:10.1007/s10741-008-9101-2


Obstructive sleep apnea (OSA), present in 5–15% of adults, is strongly associated with the incidence and poor outcome of hypertension, coronary artery disease, arrhythmia, heart failure, and stroke. Treatment of OSA completely reverses its cardiovascular consequences. In this review, we discuss the clinical evidence for the strong association between OSA and cardiovascular disease and present an argument for approaching OSA as a cardiovascular disease. We particularly focus on the causative relationship between OSA and hypertension, and on the increasingly recognized relationship between OSA and heart failure.


OSA Obstructive sleep apnea Sleep apnea Apnea Apneic episodes Sleep-disordered breathing CHF Congestive heart failure HTN Hypertension Stroke Pulmonary hypertension CAD Coronary artery disease Arrhythmia AHI Blood pressure 

Copyright information

© Springer Science+Business Media, LLC 2008

Authors and Affiliations

  • Kiran Devulapally
    • 1
  • Raymond PongonisJr.
    • 2
  • Rami Khayat
    • 1
    • 3
  1. 1.Division of Pulmonary, Critical Care, and Sleep MedicineOhio State UniversityColumbusUSA
  2. 2.Department of MedicineFeinberg School of Medicine, Northwestern UniversityChicagoUSA
  3. 3.The OSU Sleep-Heart ProgramOhio State UniversityColumbusUSA

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