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Effects of dietary myo-inositol on growth, antioxidative capacity, and nonspecific immunity in skin mucus of taimen Hucho taimen fry

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Abstract

In this study, the effects of dietary myo-inositol on the skin mucosal immunity and growth of taimen (Hucho taimen) fry were determined. Triplicate groups of 500 fish (initial weight 5.58 ± 0.15 g) were fed different diets containing graded levels of myo-inositol (28.75, 127.83, 343.83, 565.81, and 738.15 mg kg−1) until satiation for 56 days. Thereafter, the nonspecific skin mucus immune parameters, antioxidative capacity, and growth performance were measured. The skin mucus protein and the activities of alkaline phosphatase were significantly higher than those in the control group (P < 0.05). However, there were no significant differences in lysozyme activity among the treatments (P > 0.05). The antimicrobial activity and minimum inhibitory concentration of the skin mucus were increased significantly by myo-inositol supplementation (P < 0.05). The superoxide dismutase, catalase, and glutathione peroxidase activities were significantly elevated in the treatment groups (P < 0.05), whereas the malondialdehyde contents were significantly decreased (P < 0.05). Low-level myo-inositol (28.75 mg kg−1) led to a significantly lower weight gain, feed efficiency, condition factor, and survival rate compared with the other treatments (P < 0.05). In conclusion, dietary myo-inositol deficiency (28.75 mg kg−1) adversely affects the skin mucus immune parameters, antioxidative capacity, and growth performance of Hucho taimen fry.

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Funding

This study was supported by the Natural Science Funds of Heilongjiang (YQ2019C036), the China Agriculture Research System (CARS-46), the Science and Technology Project of Guizhou Province (20162502, 20162511), the Guizhou Science and Technology Plan Project (QKHZC20172532), the Guizhou Technology Innovation Team Project (QKHRCTD20154016), and the Beijing Sturgeon & Trout Innovation Team (BAIC08-2018).

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Authors and Affiliations

  1. Heilongjiang River Fisheries Research Institute, Chinese Academy of Fishery Sciences, 43, Songfa Street, Harbin, 150070, People’s Republic of China

    Chang’an Wang, Shaoxia Lu, Jinnan Li, Liansheng Wang, Yang Liu, Hongbai Liu, Shicheng Han & Jiasheng Yin

  2. College of Animal Science, Guizhou University, Guiyang, 550025, People’s Republic of China

    Haibo Jiang

Authors
  1. Chang’an Wang
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  2. Shaoxia Lu
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  3. Jinnan Li
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  4. Liansheng Wang
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  5. Haibo Jiang
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  6. Yang Liu
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  7. Hongbai Liu
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Correspondence to Hongbai Liu.

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All procedures involving animals were in accordance with the ethical standards of the institutional and/or national research committee.

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Wang, C., Lu, S., Li, J. et al. Effects of dietary myo-inositol on growth, antioxidative capacity, and nonspecific immunity in skin mucus of taimen Hucho taimen fry. Fish Physiol Biochem 46, 1011–1018 (2020). https://doi.org/10.1007/s10695-020-00766-z

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  • DOI: https://doi.org/10.1007/s10695-020-00766-z

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