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The effect of dietary fucoidan on growth, immune functions, blood characteristics and oxidative stress resistance of juvenile red sea bream, Pagrus major

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Abstract

We determined the supplementation effects of dietary fucoidan on growth, immune responses, blood characteristics, and oxidative stress resistance of juvenile red sea bream. A fishmeal (FM)-based basal diet supplemented with 0% (D1, control), 0.05% (D2), 0.1% (D3), 0.2% (D4), 0.4% (D5), and 0.8% (D6) mozuku fucoidan to formulate six experimental diets. Each diet was randomly allocated to triplicate groups of fish (3.8 g) for 60 days. Results showed that fish-fed diet D5 showed significantly higher (P < 0.05) growth performance compared to the control (D1). Diet groups D2 to D4 also showed intermediate values compared to D1. Feed conversion efficiency and protein efficiency ratio were significantly higher in diet group D5, which was not significantly different with D3. Fucoidan supplementation increased whole-body lipid, which was significantly higher in the D5 group. Condition factor (CF) was significantly higher in fish fed ≥ 0.2% fucoidan-supplemented diet groups. Diet group D5 and D4 showed significantly lower blood urea nitrogen (BUN) and aspartate aminotransferase (AST) level, respectively. Dietary fucoidan reduced the oxidative stress of fish. Among the measured nonspecific immune parameters, only peroxidase activity (PA) and total serum protein (TSP) were significantly influenced by dietary supplementation and it was higher in D4 group. Fucoidan supplementation reduces thiobarbituric acid reactive substance (TBARS) values numerically and it was lowest in fish-fed diet group D5. Under the present experimental condition, finally, we concluded that 0.3–0.4% dietary fucoidan supplementation enhanced the growth and health performance of red sea bream by increasing growth, immune response, blood characteristics, and oxidative stress resistance.

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Acknowledgements

This research was supported by the Management Expenses Grants of the United Graduate School of Agricultural Sciences, Kagoshima University provided to Dr. Shunsuke Koshio. The first author would like to thank Serge Dossou, Mr. Kokubu, and Mr. Taniguchi for their valuable help during feeding trial and sample analysis.

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Authors and Affiliations

  1. The Graduate School of Fisheries, Kagoshima University, Shimoarata 4-50-20, Kagoshima, 890-0065, Japan

    Nadia Mahjabin Sony, Manabu Ishikawa & Shunsuke Koshio

  2. Laboratory of Aquatic Animal Nutrition, Faculty of Fisheries, Kagoshima University, Shimoarata 4-50-20, Kagoshima City, 890-0056, Japan

    Nadia Mahjabin Sony, Manabu Ishikawa, Md. Sakhawat Hossain, Shunsuke Koshio & Saichiro Yokoyama

  3. Department of Aquaculture, Faculty of Fisheries, Sylhet Agricultural University, Sylhet, 3100, Bangladesh

    Md. Sakhawat Hossain

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  1. Nadia Mahjabin Sony
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  2. Manabu Ishikawa
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  3. Md. Sakhawat Hossain
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  4. Shunsuke Koshio
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  5. Saichiro Yokoyama
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Correspondence to Md. Sakhawat Hossain.

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Sony, N.M., Ishikawa, M., Hossain, M.S. et al. The effect of dietary fucoidan on growth, immune functions, blood characteristics and oxidative stress resistance of juvenile red sea bream, Pagrus major. Fish Physiol Biochem 45, 439–454 (2019). https://doi.org/10.1007/s10695-018-0575-0

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