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Plasma FITC-dextran exchange between the primary and secondary circulatory systems in the Atlantic cod, Gadus Morhua

Fish Physiology and Biochemistry volume 34, pages 245–249 (2008)Cite this article

Abstract

Fluorescein isothiocyanate dextran (FITC-dextran) exchange between the primary (PCS) and secondary (SCS) circulatory systems in the Atlantic cod, Gadus morhua (Linnaeus, 1752), were studied using 20-kDa (n = 4) and 500-kDa (n = 4) FITC-dextran. In order to give a qualitative perspective of the general connection between the PCS and SCS, distribution of plasma-borne tracers (FITC-dextran) in the PCS and SCS were examined. In this study, a total of eight cod were cannulated in the ventral aorta (PCS) and dorsal cutaneous vessel (SCS), for investigation of FITC-dextran disappearance in the PCS and its subsequent appearance in the SCS. FITC-dextran of both sizes was found to be in equilibrium between the PCS and SCS in less than 20 min. This indicates a profound connection between the PCS and SCS in the Atlantic cod, and rapid mixing of tracers between the PCS and SCS. The destination of the injected 500-kDa FITC-dextran was also examined, and it was observed that of the 500-kDa FITC-dextran lost from the primary and secondary vascular systems, 63.0 ± 9.2% could be recovered from the liver

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Authors and Affiliations

  1. Marine Biological Laboratory, University of Copenhagen, Strandpromenaden 5, Helsingor, 3000, Denmark

    Claes Fischer & John Fleng Steffensen

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  1. Claes Fischer
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  2. John Fleng Steffensen
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Correspondence to Claes Fischer.

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Fischer, C., Steffensen, J.F. Plasma FITC-dextran exchange between the primary and secondary circulatory systems in the Atlantic cod, Gadus Morhua . Fish Physiol Biochem 34, 245–249 (2008). https://doi.org/10.1007/s10695-007-9183-0

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  • DOI: https://doi.org/10.1007/s10695-007-9183-0

Keywords

  • Secondary circulation
  • Plasma exchange
  • Gadus morhua
  • FITC-dextran

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