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The current status of chemoprevention in FAP

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References

  1. KP Nugent AD Spigelman RKS Phillips (1993) ArticleTitleLife expectancy after colectomy and ileorectal anastomosis for familial adenomatous polyposis Dis Colon Rectum 36 1059–62 Occurrence Handle8223060 Occurrence Handle1:STN:280:ByuD3sfktlU%3D Occurrence Handle10.1007/BF02047300

    Article  PubMed  CAS  Google Scholar 

  2. HH Miller LJ Bauman DR Friedman et al. (1986–87) ArticleTitlePsychosocial adjustment of familial polyposis patients and participation in a chemoprevention trial Int J Psychiatry Med 16 IssueID3 211–30 Occurrence Handle10.2190/DAE0-EWPX-R7D6-LFNY

    Article  Google Scholar 

  3. WR Waddell RW Longhry (1983) ArticleTitleSulindac for polyposis of the colon J Surg Oncology 24 83–7 Occurrence Handle1:STN:280:BiyB1MrptlM%3D

    CAS  Google Scholar 

  4. D Labayle D Fischer P Viehl et al. (1991) ArticleTitleSulindac causes regression of rectal polyps in familial adenomatous polyposis Gastroenterology 101 635–9 Occurrence Handle1650315 Occurrence Handle1:STN:280:By6A3MjktVE%3D

    PubMed  CAS  Google Scholar 

  5. CM Cruz LM Hylind K Romans et al. (2002) ArticleTitleLong term treatment with sulindac in familial adenomatous polyposis: a prospective cohort study Gastroenterology 122 IssueID3 641–5 Occurrence Handle10.1053/gast.2002.31890

    Article  Google Scholar 

  6. I Guldenschuh R Hurlimannn A Muller et al. (2001) ArticleTitleRelationship between APC genotype, polyp distribution and oral sulindac treatment in the colon and rectum of patients with familial adenomatous polyposis Dis Colon Rectum 44 IssueID8 1090–7 Occurrence Handle11535846 Occurrence Handle1:STN:280:DC%2BD3MvpsFShtA%3D%3D Occurrence Handle10.1007/BF02234627

    Article  PubMed  CAS  Google Scholar 

  7. G Winde HG Gumbinger F Kemper et al. (1993) ArticleTitleThe NSAID sulindac reverses rectal adenomas in colectomised patients with familial adenaomtous polyposis: Clinical results of a dose-finding study on rectal sulindac administration Int J Colorectal Dis 8 IssueID1 13–7 Occurrence Handle8388011 Occurrence Handle1:STN:280:ByyB28%2FjtlY%3D Occurrence Handle10.1007/BF00341270

    Article  PubMed  CAS  Google Scholar 

  8. CS Richard T Berk BV Bapat et al. (1997) ArticleTitleSulindac for periampullary polyps in FAP patients Int J Colorectal Dis 12 IssueID1 14–8 Occurrence Handle9112144 Occurrence Handle1:STN:280:ByiB28njsFQ%3D Occurrence Handle10.1007/s003840050071

    Article  PubMed  CAS  Google Scholar 

  9. HS Debinski J Trojan KP Nugent et al. (1995) ArticleTitleEffect of sulindac on small polyps in familial adenomatous polyposis Lancet 345 855–66 Occurrence Handle7898240 Occurrence Handle1:STN:280:ByqB3cngt1w%3D Occurrence Handle10.1016/S0140-6736(95)92989-4

    Article  PubMed  CAS  Google Scholar 

  10. KP Nugent KCR Farmer AD Spigelman et al. (1993) ArticleTitleRandomised controlled trial of the effects of sulindac on duodenal and rectal polyposis and cell proliferation in patients with familial adenomatous polyposis Br J Surg 80 1618–9 Occurrence Handle8298943 Occurrence Handle1:STN:280:ByuC3s%2Fgs1M%3D

    PubMed  CAS  Google Scholar 

  11. Y Niv GM Fraser (1994) ArticleTitleAdenocarcinoma in the rectal remnant in familial polyposis coli is not prevented by sulindac therapy Gastroenterology 107 854–7 Occurrence Handle8076772 Occurrence Handle1:STN:280:ByuA2MjjvVI%3D

    PubMed  CAS  Google Scholar 

  12. FM Giardello RA Casero SR Hamilton et al. (2004) ArticleTitleProstanoids, ornithine decarboxylase and polyamines in primary chemoprevention of familial adenomatous polyposis Gastroenterology 49 1259–61

    Google Scholar 

  13. T Akasu T Yokoyama K Sugihara et al. (2002) ArticleTitlePeroral sustained release indomethacin treatment for rectal adenomas in familial adenomatous polyposis: A pilot study Hepatogastroenterology 49 1259–61 Occurrence Handle12239919

    PubMed  Google Scholar 

  14. M Oshima JE Dinchuk SL Kargman et al. (1996) ArticleTitleSuppression of intestinal polyposis in APCΔ716 knockout mice by inhibition of cyclooxygenase 2 (COX-2) Cell 87 803–9 Occurrence Handle8945508 Occurrence Handle1:CAS:528:DyaK28XntlymsLc%3D Occurrence Handle10.1016/S0092-8674(00)81988-1

    Article  PubMed  CAS  Google Scholar 

  15. T Kawamori CV Rao K Seibert et al. (1998) ArticleTitleChemopreventative activity of celecoxib, a specific cyclooxygenase-2 inhibitor against colon carcinogenesis Ca Res 58 409–12 Occurrence Handle1:CAS:528:DyaK1cXnsFejtw%3D%3D

    CAS  Google Scholar 

  16. GD Steinbach PM Lynch RKS Phillips et al. (2000) ArticleTitleThe effect of celecoxib, a cyclooxygenase-2 inhibitor, in familial adenomatous polyposis N Engl J Med 342 1946–52 Occurrence Handle10874062 Occurrence Handle1:CAS:528:DC%2BD3cXltVCnu7Y%3D Occurrence Handle10.1056/NEJM200006293422603

    Article  PubMed  CAS  Google Scholar 

  17. RKS Phillips MH Wallace PM Lynch et al. (2002) ArticleTitleA randomised double blind placebo controlled study of celecoxib, a selective cyclooxygenase -2 inhibitor on duodenal polyposis in familial adenomatous polyposis Gut 50 657–60 Occurrence Handle10.1136/gut.50.6.857

    Article  Google Scholar 

  18. T Higuchi T Iwama K Yoshinaga et al. (2003) ArticleTitleA randomized, double-blind, placebo-controlled trial of the effects of rofecoxib, a selective cyclooxygenase-2 inhibitor, on rectal polyps in familial adenomatous polyposis patients Clin Cancer Res 9 IssueID13 4756–60 Occurrence Handle14581346 Occurrence Handle1:CAS:528:DC%2BD3sXosVGjsLs%3D

    PubMed  CAS  Google Scholar 

  19. A Hallak L Baron R Samir et al. (2003) ArticleTitleRofecoxib reduces polyp recurrence in familial polyposis Dig Dis Sci 49 IssueID10 1998–2002 Occurrence Handle10.1023/A:1026130623186

    Article  Google Scholar 

  20. GD Stoner GT Budd R Ganapathi et al. (1999) ArticleTitleSulindac sulfone induced regression of rectal polyps in patients with familial adenomatous polyposis Adv Exp Med Biol 470 45–53 Occurrence Handle10709673 Occurrence Handle1:CAS:528:DC%2BD3cXlsV2kt7c%3D

    PubMed  CAS  Google Scholar 

  21. MJ Hill (1975) ArticleTitleMetabolic epidemiology of dietary factors in large bowel cancer Cancer Res 35 3398–402 Occurrence Handle1104151 Occurrence Handle1:STN:280:CSmD28vht1A%3D

    PubMed  CAS  Google Scholar 

  22. JC Mathers I Mickleburgh PC Chapman et al. (2003) ArticleTitleCan resistant starch and / or prevent the development of colonic neoplasia? The Concerted Action Polyp Prevention (CAPP) 1 study Proc Nutr Soc 62 51–7 Occurrence Handle12740057 Occurrence Handle1:CAS:528:DC%2BD3sXjslyhtLY%3D Occurrence Handle10.1079/PNS2002236

    Article  PubMed  CAS  Google Scholar 

  23. JI Lew Y Guo RK Kim et al. (2002) ArticleTitleReduction of intestinal neoplasia with adenomatous polyposis coli gene replacement and COX-2 inhibition is additive J Gastrointest Surg 6 563–8 Occurrence Handle12127122 Occurrence Handle10.1016/S1091-255X(01)00042-7

    Article  PubMed  Google Scholar 

  24. HJ Bussey JJ DeCosse EE Deschner et al. (1982) ArticleTitleA randomized trial of ascorbic acid in polyposis coli Cancer 50 IssueID7 1434–9 Occurrence Handle7049351 Occurrence Handle1:STN:280:Bi2B2Mfos1c%3D Occurrence Handle10.1002/1097-0142(19821001)50:7<1434::AID-CNCR2820500733>3.0.CO;2-F

    Article  PubMed  CAS  Google Scholar 

  25. JJ DeCosse HH Miller ML Lesser (1989) ArticleTitleEffect of wheat fiber and vitamins C and E on rectal polyps in patients with familial adenomatous polyposis J Natl Cancer Inst 81 IssueID17 1290–7 Occurrence Handle2549261 Occurrence Handle1:STN:280:BiaA283lt1E%3D

    PubMed  CAS  Google Scholar 

  26. MG Thomas JP Thomson RC Williamson (1993) ArticleTitleOral calcium inhibits rectal proliferation in familial adenomatous polyposis Br J Surg 80 IssueID40 449–501

    Google Scholar 

  27. S Perkins RD Verschoyle K Hill et al. (2002) ArticleTitleChemoprevention efficacy and pharmacokinetics of curcumin in the min/+ mouse, a model of familial adenomatous polyposis Cancer Epidemiol Biomarkers Prev 11 535–40 Occurrence Handle12050094 Occurrence Handle1:CAS:528:DC%2BD38Xltlantrg%3D

    PubMed  CAS  Google Scholar 

  28. SH Erdman NA Ignatenko MB Powell et al. (1999) ArticleTitleAPC-dependant changes in expression of genes influencing polyamine metabolism, and consequences for gastrointestinal carcinogenesis, in the Min mouse Carcinogenesis 20 1709–13 Occurrence Handle10469614 Occurrence Handle1:CAS:528:DyaK1MXlvFWqsLk%3D Occurrence Handle10.1093/carcin/20.9.1709

    Article  PubMed  CAS  Google Scholar 

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Wallace, M.H., Lynch, P.M. The current status of chemoprevention in FAP. Familial Cancer 5, 289–294 (2006). https://doi.org/10.1007/s10689-005-5676-0

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