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50 Hz alternating extremely low frequency magnetic fields affect excitability, firing and action potential shape through interaction with ionic channels in snail neurones

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Abstract

In spite of growing concern about the influence of magnetic fields on biological systems, the interaction between extremely low frequency magnetic field (ELF magnetic fields) and biological structures at the cellular level remains obscure. The aim of this study was to investigate if 50 Hz magnetic fields could have an effect on the neuronal excitability and firing responses. Under Current-Clamp condition, exposure to 50 Hz ELF magnetic fields at 2 mT or 0.8 mT intensities resulted in an increase in the peak amplitude of action potential and after hyperpolaization potential in a time dependent manner. Both magnetic field intensities decreased also the firing frequency and the duration of action potential. Taken together, these data suggest that 50 Hz ELF magnetic fields at 2 mT or 0.8 mT intensities may change the electrophysiological behavior of neuronal cells and underlying ion channel currents.

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Authors and Affiliations

  1. Neuroscience Research Center and Department of Physiology, Medical Faculty, Shaheed Beheshti Medical Sciences University, Evin, P.O. Box 19835-181, Tehran, Iran

    Mehri Kaviani Moghadam & Mahyar Janahmadi

  2. Department of Medical Physics, Medical Faculty, Tarbiat Modarres University, Tehran, Iran

    Mehri Kaviani Moghadam & Saied Mohammad Firoozabadi

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  1. Mehri Kaviani Moghadam
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  2. Saied Mohammad Firoozabadi
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  3. Mahyar Janahmadi
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Correspondence to Mahyar Janahmadi.

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Moghadam, M.K., Firoozabadi, S.M. & Janahmadi, M. 50 Hz alternating extremely low frequency magnetic fields affect excitability, firing and action potential shape through interaction with ionic channels in snail neurones. Environmentalist 28, 341–347 (2008). https://doi.org/10.1007/s10669-007-9143-3

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  • DOI: https://doi.org/10.1007/s10669-007-9143-3

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