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The use of cell phone and insight into its potential human health impacts

Environmental Monitoring and Assessment volume 188, Article number: 221 (2016) Cite this article

Abstract

The rapid evolution of mobile phone technology has raised public concern about its possible association with adverse health effects. Given the huge number of mobile phone users at present days, even simple adverse health effects could have major implications. This article reviews the present knowledge concerning the health effects stemming from the use of cellular phones by emphasizing adverse biological effects, epidemiological issues, and indirect health effects. A line of epidemiological evidence suggests that there is no concrete association between mobile phone radiation and cancer. The evidence regarding the occurrence of cancer due to exposure to the radio frequency energy of mobile phones is nonetheless conflicting. Consequently, long-term research in this field is necessary to account for the vital issue of this scientific research to the public in a meaningful way.

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References

  • Abdel-Rassoul, G., El-Fateh, O. A., Salem, M. A., Michael, A., Farahat, F., El-Batanouny, M., & Salem, E. (2007). Neurobehavioral effects among inhabitants around mobile phone base stations. Neurotoxicology, 28(2), 434–440.

    CAS  Article  Google Scholar 

  • Acharya, J. P., Indranil Acharya, I., & Waghrey, D. (2013). A study on some psychological health effects of cell-phone usage amongst college going students. International Journal of Medical Research and Health Sciences, 2(3), 388–394.

    Article  Google Scholar 

  • Adams, J. A., Galloway, T. S., Mondal, D., Esteves, S. C., & Mathews, F. (2014). Effect of mobile telephones on sperm quality: a systematic review and meta-analysis. Environment International, 70, 106–112.

    Article  Google Scholar 

  • Agarwal, A., & Durairajanayagam, D. (2015). Are men talking their reproductive health away? Asian Journal of Andrology, 17(3), 433–434.

    Google Scholar 

  • Agarwal, A., Deepinder, F., Sharma, R. K., Ranga, G., & Li, J. (2008). Effect of cell phone usage on semen analysis in men attending infertility clinic: an observational study. Fertility and Sterility, 89, 124–128.

    Article  Google Scholar 

  • Agarwal, A., Desai, N. R., Makker, K., Varghese, A., Mouradi, R., Sabanegh, E., & Sharma, R. (2009). Effects of radiofrequency electromagnetic waves (RF-EMW) from cellular phones on human ejaculated semen: an in vitro pilot study. Fertility and Sterility, 92(4), 1318–1325.

    Article  Google Scholar 

  • Aitken, R. J., Bennetts, L. E., Sawyer, D., et al. (2005). Impact of radio frequency electromagnetic radiation on DNA integrity in the male germline. International Journal of Andrology, 28(3), 171–179.

    CAS  Article  Google Scholar 

  • Akinyemi, K. O., Atapu, A. D., Adetona, O. O., & Coker, A. O. (2009). The potential role of mobile phones in the spread of bacterial infections. Journal of Infection in Developing Countries, 3(8), 628–632.

    Article  Google Scholar 

  • Awadalla, H. (2013). Health effects of mobile phone. Webmed Central Public Health, 4(1), WMC003946.

    Google Scholar 

  • Aydin, D., Feychting, M., Schüz, Jo., et al. (2011). Mobile phone use and brain tumors in children and adolescents: a multicenter case-control study. Published online, July 27, 2011. NCI Journal of the National Cancer Institute.

  • Beasley, J. S., & Miller, G. M. (2008). Modern electronic communication 9th edition. PHI Learning, 9, 4–5 [ISBN 978–0132251136].

    Google Scholar 

  • Bhalerao, G. A., Zope, R. G., Khaire, G. B., & Tambe, B. P. (2013). Human brain with EMR of cell phone. International Journal of Modern Engineering Research, 3(1), 307–310.

    Google Scholar 

  • Bhargavi, K., Balachandrudu, K. E., & Nageswar, P. (2013). Mobile phone radiation effects on human health. International Journal of Computational Engineering Research, 3(4), 196–203.

    Google Scholar 

  • Billieux, J. (2012). Problematic use of the mobile phone: a literature review and a pathways model. Current Psychiatry Reviews, 8(4), 299–307.

    Article  Google Scholar 

  • Cardis, E., Richardson, L., Deltour, I., Armstrong, B., Feychting, M., Christoffer Johansen, C., et al. (2007). The INTERPHONE study: design, epidemiological methods, and description of the study population. European Journal of Epidemiology, 22, 647–664.

    Article  Google Scholar 

  • Dasari, K. B., White, S. M., & Pateman, J. (2011). Survey of iPhone usage among anaesthetists in England. Anaesthesia, 66(7), 630–631.

    CAS  Article  Google Scholar 

  • De Iuliis, G. N., Newey, R., King, B., & Aitken, R. J. (2009). Mobile phone radiation induces reactive oxygen species production and DNA damage in human spermatozoa in vitro. PloS One, 4(7), e6446.

    Article  Google Scholar 

  • Deepinder, F., Makker, K., & Agarwal, A. (2007). Cell phones and male infertility: dissecting the relationship. Reproductive Biomedicine, 15(3), 266–270.

    Article  Google Scholar 

  • Deltour, I., Auvinen, A., Feychting, M., et al. (2012). Mobile phone use and incidence of glioma in the Nordic countries 1979–2008: consistency check. Epidemiology, 23(2), 301–307.

    Article  Google Scholar 

  • Divan, H. A., Kheifets, L., Obel, C., & Olsen, J. (2010). Cell phone use and behavioural problems in young children. Journal of Epidemiology and Community Health, 66, 524–529.

    Article  Google Scholar 

  • Drouin, M., Kaiser, D. H., Daniel, A., & Miller, D. A. (2012). Phantom vibrations among undergraduates: prevalence and associated psychological characteristics. Computers in Human Behavior, 28, 1490–1496.

    Article  Google Scholar 

  • Falzone, N., Huyser, C., Becker, P., Leszezynski, D. R., & Franken, D. R. (2011). The effect of pulsed 900-MHz GSM mobile phone radiation on the acrosome reaction, head morphometry and zona binding of human spermatozoa. International Journal of Andrology, 34(1), 20–26.

    CAS  Article  Google Scholar 

  • Faruque, M. R. I., Islam, M. T., & Misran, N. (2011) Analysis of electromagnetic absorption in mobile phones using metamaterials. Electromagnetics, 31(3), 215–232

  • FCC. (2011). Specific absorption rate (SAR) for cell phones: what it means for you. Guide Accessed online.

  • Fejes, I., Zavacki, Z., Szollosi, J., Koloszar Daru, J., Kovacs, L., & Pal, A. (2005). Is there a relationship between cell phone use and semen quality? Archives of Andrology, 51, 385–393.

    CAS  Article  Google Scholar 

  • Gul, A., Celebi, H., & Ugras, S. (2009). The effects of microwaves emitted by cellular phones on ovarian follicles in rats. Archives of Gynecology and Obstetrics, 280(5), 729–733.

    Article  Google Scholar 

  • Gutschi, T., AI-Ali, B. M., Shamloul, R., Pummer, K., & Trummer, H. (2011). Impact of cell phone use on men’s semen parameters. Andrologia, 43(5), 312–316.

    CAS  Article  Google Scholar 

  • Hamada, A. J., Aspinder Singh, A., & Agarwal, A. (2011). Cell phones and their impact on male fertility: fact or fiction. The Open Reproductive Science Journal, 5, 125–137.

    Google Scholar 

  • Hardell, L., Mild, K. H., & Carlberg, M. (2002). Case-control study on the use of cellular and cordless phones and the risk for malignant brain tumours. International Journal of Radiation Biology, 78, 931–936.

    CAS  Article  Google Scholar 

  • Hardell, L., Carlberg, M., & Mild, K. H. (2006). Pooled analysis of two case–control studies on use of cellular and cordless telephones and the risk for malignant brain tumours diagnosed in 1997–2003. International Archives Environmental Health, 79, 630–639.

    Article  Google Scholar 

  • Hardell, L., Carlberg, M., & Mild, K. H. (2011). Pooled analysis of case-control studies on malignant brain tumours and the use of mobile and cordless phones including living and deceased subjects. International Journal of Oncology, 38(5), 1465–1474.

    Article  Google Scholar 

  • Havas, M., Marrongelle, J., Pollner, B., Kelley, E., Rees, C. R. G., & Tully, L. (2010). Provocation study using heart rate variability shows microwave radiation from 2.4 GHz cordless phone affects autonomic nervous system. European Journal of Oncology Library, 5, 273–300.

    Google Scholar 

  • Hepworth, S. J., Schoemaker, M. J., Muir, K. R., Swerdlow, A. J., Tongeren, M. J. A., & McKinney, P. A. (2006). Mobile phone use and risk of glioma in adults: case-control study. BMJ, 332, 883.

    Article  Google Scholar 

  • IARC (International Agency for Research on Cancer). (2013). IARC classifies radiofrequency electromagnetic fields as possibility carcinogenic to humans. International Agency for Research on Cancer. [Available at http://monographs.iarc.fr/ENG/Classification/].

  • Iftekharuddin, A.S.M., Ferdous, J. (2010). Radiation exposure of cell phones & its impact on human health—a case study in South Asia (Bangladesh) and some recommendations. Journal of Theoretical and Applied Information Technology. 15–21.

  • Imai, N., Kawabe, M., Hikage, T., Nojima, T., Takahashi, S., & Shirai, T. (2011). Effects on rat testis of 1.95-GHz W-CDMA for IMT-2000 cellular phones. Systems Biology in Reproductive Medicine, 57(4), 204–209.

    Article  Google Scholar 

  • Inskip, P. D., Hoover, R. N., & Devesa, S. S. (2010). Brain cancer incidence trends in relation to cellular telephone use in the United States. Neuro-Oncology, 12(11), 1147–1151.

    Article  Google Scholar 

  • ITU (International Telecommunications Union). (2013). Global mobile statistics 2013 Part A: mobile subscribers; handset market share; mobile operators. International Telecommunications Union. [Available at http://www.itu.int/home].

  • Jauchem, J. R. (2008). Effects of low-level radio-frequency (3 kHz to 300 GHz) energy on human cardiovascular, reproductive, immune, and other systems: a review of the recent literature. International Journal of Hygiene and Environmental Health, 211, 1–29.

    Article  Google Scholar 

  • Jorgensen, T. J., & Marko, M. (2011). Communicating radiation risks to the public. Radiation Protection Dosimetry, 145(4), 339.

    Article  Google Scholar 

  • Jorm, C. M., & O’Sullivan, G. (2012). Laptops and smartphones in the operating theatre—how does our knowledge of vigilance, multi-tasking and anaesthetist performance help us in our approach to this new distraction? Anaesthesia and Intensive Care, 40(1), 71–78.

    Google Scholar 

  • Kabir, E., & Kim, K.-H. (2011). An investigation on hazardous and odorous pollutants emission during cooking activities. Journal of Hazardous Materials, 188, 443–454.

    CAS  Article  Google Scholar 

  • Karger, C. P. (2005). Mobile phones and health: a literature overview. Zeitschrift für Medizinische Physik, 15, 73–85.

    Article  Google Scholar 

  • Karinen, A., Heinävaara, S., Nylund, R., & Leszczynski, D. (2008). Mobile phone radiation might alter protein expression in human skin. BMC Genomics, 9, 77. doi:10.1186/1471-2164-9-77.

    Article  Google Scholar 

  • Kesari, K. K., & Behari, J. (2012). Evidence for mobile phone radiation exposure effects on reproductive pattern of male rats: role of ROS. Electromagnetics Biology and Medicine, 31(3), 213–222.

    CAS  Article  Google Scholar 

  • Kesari, K. K., Kumar, S., & Behari, J. (2011). Effects of radiofrequency electromagnetic wave exposure from cellular phones on the reproductive pattern in male Wistar rats. Applied Biochemistry and Biotechnology, 164(4), 546–559.

    CAS  Article  Google Scholar 

  • Kheifets, L., Repacholi, M., Saunders, R., & van Deventer, E. (2005). The sensitivity of children to electromagnetic fields. Pediatrics, 116(2), e303–e313.

    Article  Google Scholar 

  • Khurana, V. G., Teo, C., Kundi, M., Hardell, L., & Carlberg, M. (2009). Cell phones and brain tumors: a review including the long-term epidemiologic data. Surgical Neurology, 72, 205–215.

    Article  Google Scholar 

  • Kim, K.-H., Shonm, Z.-H., Nguyenm, H., & Jeon, E.-C. (2011a). A review of chlorofluorocarbons and their halocarbon alternatives in air. Atmospheric Environment, 45, 1369–1382.

    CAS  Article  Google Scholar 

  • Kim, K.-H., Jahan, S. A., & Kabir, E. (2011b). A review of diseases associated with household air pollution due to the use of biomass fuels. Journal of Hazardous Materials, 19, 425–431.

    Article  Google Scholar 

  • Kim, K.-H., Jahan, S. A., Kabir, E., & Brown, R. J. C. (2013). A review of airborne polycyclic aromatic hydrocarbons (PAHs) and their human health effects. Environment International, 60, 71–80.

    CAS  Article  Google Scholar 

  • Kim, K.-H., Kabir, E., & Jahan, S. A. (2015). A review on the human health impact of airborne particulate matter. Environment International, 74, 136–143.

    CAS  Article  Google Scholar 

  • Kimata, H. (2002). Enhancement of allergic skin wheal responses by microwave radiation from mobile phones in patients with atopic eczema/dermatitis syndrome. International Archives of Allergy and Immunology, 129(4), 348–350.

    CAS  Article  Google Scholar 

  • Kundi, M. (2008). The controversy about a possible relationship between mobile phone use and cancer. Environmental Health Perspectives doi: 10.1289/ehp.11902 (available at http://dx.doi.org/) Online 26September 2008).

  • Lahkola, A., Auvinen, A., Raitanen, J., Schoemaker, M. J., Christensen, H. C., Feychting, M., Johansen, C., Klaeboe, L., Lönn, S., Swerdlow, A. J., Tynes, T., & Salminen, T. (2007). Mobile phone use and risk of glioma in 5 North European countries. International Journal of Cancer, 120, 1769–1775.

    CAS  Article  Google Scholar 

  • Lee, Y. J., Yoo, C. G., Lee, C. T., Chung, H. S., Kim, Y. W., Han, S. K., & Yim, J. J. (2013). Contamination rates between smart cell phones and non-smart cell phones of healthcare workers. Journal of Hospital Medicine, 8(3), 144–147.

    Article  Google Scholar 

  • Levis, A. G., Minicuci, N., Ricci, P., Gennaro, V., & Garbisa, S. (2011). Mobile phones and head tumours. The discrepancies in cause-effect relationships in the epidemiological studies—how do they arise? Environmental Health, 10, 59–65.

    Article  Google Scholar 

  • Lim, J.-M., Lee, J.-H., Chung, Y.-S., Moon, J.-H., & Kim, K.-H. (2009). Risk assessment of inhalation exposure for airborne toxic metals using instrumental neutron activation analysis. Journal of Radioanalytical and Nuclear Chemistry, 281(2), 185–188.

    CAS  Article  Google Scholar 

  • Little, M. P., Rajaraman, P., Curtis, R. E., et al. (2012). Mobile phone use and glioma risk: comparison of epidemiological study results with incidence trends in the United States. British Medical Journal, 344, e1147.

    CAS  Article  Google Scholar 

  • Lloyd, M. L., Herberman, R. B., Philips, A., & Lee, D. D. (2012). Re: Mobile phone use and brain tumors in children and adolescents: a multicenter case–control study. Journal of the National Cancer Institute, 104(8), 635.

    Google Scholar 

  • Lönn, S., Ahlbom, A., Hall, P., & Feychting, M. (2005). Long-term mobile phone use and brain tumor risk. American Journal of Epidemiology, 161(6), 526–535.

    Article  Google Scholar 

  • Mahajan, A., & Singh, M. (2012). Human health and electromagnetic radiation. International Journal of Engineering and Innovative Technology (IJEIT), 1(6), 95–97 [ISSN 2277–3754].

    Google Scholar 

  • Mortazavi, S. M., Daiee, E., Yazdi, A., Khiabani, K., Kavousi, A., Vazirinejad, R., Behnejad, B., Ghasemi, M., & Mood, M. B. (2008). Mercury release from dental amalgam restorations after magnetic resonance imaging and following mobile phone use. Pakistan Journal of Biological Sciences, 11(8), 1142–1146.

    CAS  Article  Google Scholar 

  • Nittby, H., Grafström, G., Tian, D. P., Malmgren, L., Brun, A., Persson, B. R., Salford, L. G., & Eberhardt, J. (2008). Cognitive impairment in rats after long-term exposure to GSM-900 mobile phone radiation. Bioelectromagnetics, 29(3), 219–232.

    Article  Google Scholar 

  • NRPB (National Radiological Protection Board). (2011). Mobile telephony and health: exposures from mobile phones. NRPB Information Sheets, December 2011, Chilton, UK

  • Otitoloju, A. A., Obe, I. A., Adewale, O. A., Otubanjo, O. A., & Osunkalu, V. O. (2010). Preliminary study on the reduction of sperm head abnormalities in mice, Mus musculus, exposed to radiofrequency radiations from global system for mobile communication base stations. Bulletin of Environmental Contamination and Toxicology, 84(1), 51–54.

    CAS  Article  Google Scholar 

  • Otto, M., Ernst, K., & Muhiendahi, V. (2007). Electromagnetic fields: do they play a role in children’s environmental health (CEH)? International Journal of Hygiene and Environmental Health, 210, 635–644.

    Article  Google Scholar 

  • Oulasvirta, A., Rattenbury, T., Lingyi, M., Raita, E. (2011). Habits make smartphone use more pervasive. Pers Ubiquit Comput, Springer-Verlag London Limited.

  • Panda, N. K., Modi, R., Munjal, S., & Virk, R. S. (2011). Auditory changes in mobile users: is evidence forthcoming? Otolaryngology and Head and Neck Surgery, 144(4), 581–585.

    Article  Google Scholar 

  • Rağbetli, M. C., Aydinlioğlu, A., Koyun, N., Rağbetli, C., Bektas, S., & Ozdemir, S. (2010). The effect of mobile phone on the number of Purkinje cells: a stereological study. International Journal of Radiation Biology, 86(7), 548–554.

    Article  Google Scholar 

  • Rahman, M. M., & Kim, K.-H. (2012). Exposure to hazardous volatile pollutants back diffusing from automobile exhaust systems. Journal of Hazardous Materials, 241–242, 267–278.

    Article  Google Scholar 

  • Ranjan, R., Ranjan, M., & Kumar, R. (2014). In preliminary data, cell phone users have longer ABR latencies. Hearing Journal, 67(3), 34–36.

    Article  Google Scholar 

  • Rezk, A. Y., Abdulqawi, K., Mustafa, R. M., Abo El-Azm, T. M., & Al-Inany, H. (2008). Fetal and neonatal responses following maternal exposure to mobile phones. Saudi Medical Journal, 29(2), 218–223.

    Google Scholar 

  • Sage, C., & Carpenter, D. O. (2009). Public health implications of wireless technologies. Pathophysiology, 16(2–3), 233–246.

    Article  Google Scholar 

  • Salama, N., Kishimoto, T., & Kanayama, H. O. (2010). Effects of exposure to a mobile phone on testicular function and structure in adult rabbit. International Journal of Andrology, 33(1), 88–94.

    Article  Google Scholar 

  • Sallomi, A. H. (2012). A theoretical approach for SAR calculation in human head exposed to RF signal. Journal of Engineering and Development, 16(4), 304–313 [ISSN 1813–7822].

    Google Scholar 

  • Schoemaker, M. J., Swerdlow, A. J., Ahlbom, A., Auvinen, A., Blaasaas, K. G., Cardis, E., Christensen, H. C., Feychting, M., Hepworth, S. J., Johansen, C., Klaeboe, L., Lönn, S., McKinney, P. A., Muir, K., Raitanen, J., Salminen, T., Thomsen, J., & Tynes, T. (2005). Mobile phone use and risk of acoustic neuroma: results of the Interphone case-control study in five North European countries. British Journal of Cancer, 93, 842–848.

    CAS  Article  Google Scholar 

  • Schüz, J., Jacobsen, R., Olsen, J. H., Boice, J. D., McLaughlin, J. K., & Johansen, C. (2006). Cellular telephone use and cancer risk: update of a nationwide Danish cohort. Journal of the National Cancer Institute, 98, 1707–1713.

    Article  Google Scholar 

  • Singh, S. and Kapoor, N. (2014). Health implications of electromagnetic fields, mechanisms of action, and research needs. Article ID 198609, http://dx.doi.org/10.1155/2014/198609.

  • Subba, S.H., Mandelia, C., Pathak, V., Reddy, D., Goel, A., Tayal, A., Nair, S., Nagaraj, K. (2013). Ringxiety and the mobile phone usage pattern among the students of a medical college in South India. Journal of Clinical and Diagnostic Research. 205–209.

  • Susaya, J., Kim, K.-H., Ahn, J.-W., Jung, M.-C., & Kang, C.-H. (2010). BBQ charcoal combustion as an important source of trace metal exposure to humans. Journal of Hazardous Materials, 176, 932–937.

    CAS  Article  Google Scholar 

  • Takebayashi, T., Akiba, S., Kikuchi, Y., Taki, M., Wake, K., Watanabe, S., & Yamaguchi, N. (2006). Mobile phone use and acoustic neuroma risk in Japan. Occupational and Environmental Medicine, 63(12), 802–807.

    CAS  Article  Google Scholar 

  • Thomee, S., Härenstam, A., & Hagberg, M. M. (2011). Mobile phone use and stress, sleep disturbances, and symptoms of depression among young adults—a prospective cohort study. BMC Public Health, 11, 66.

    Article  Google Scholar 

  • Thorat, K.D., Shelke, V. (2013). Effects of mobile phone radiation on heart rate variation in healthy volunteers. Research Journal of Pharmaceutical, Biological and Chemical Sciences. 4(1):840–845. [ISSN: 0975–8585].

  • Uddin, A. S. M. I., & Ferdous, J. (2010). Radiation exposure of cell phones and its impacts on human health—a case study in South Asia (Bangladesh) and some recommendation. Journal of Theoretical & Applied Information Technology, 19(1/2), 15.

    Google Scholar 

  • Ulger, F., Esen, S., Dilek, A., Yanik, K., Gunaydin, M., & Leblebicioglu, H. (2009). Are we aware how contaminated our mobile phones with nosocomial pathogens? Annals of Clinical Microbiology and Antimicrobials, 8, 7. doi:10.1186/1476-0711-8-7.

    Article  Google Scholar 

  • Wdowiak, A., Wdowiak, L., & Wiktor, H. (2007). Evaluation of the effect of using mobile phones on male fertility. Annals Agriculture Environmental Medicine (AAEM), 14(1), 169–172.

    Google Scholar 

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Acknowledgments

This study was supported by a grant from the National Research Foundation of Korea (NRF) funded by the Ministry of Education, Science and Technology (MEST) (No. 2009-0093848).

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Affiliations

  1. Department of Civil and Environmental Engineering, Hanyang University, Seoul, 04763, Republic of Korea

    Ki-Hyun Kim

  2. Department of Farm, Power and Machinery, Bangladesh Agricultural University, Mymensingh, 2202, Bangladesh

    Ehsanul Kabir

  3. BRAC Clinic, Rayerbazar, Dhaka, 2202, Bangladesh

    Shamin Ara Jahan

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  1. Ki-Hyun Kim
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  2. Ehsanul Kabir
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Correspondence to Ki-Hyun Kim.

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Kim, KH., Kabir, E. & Jahan, S.A. The use of cell phone and insight into its potential human health impacts. Environ Monit Assess 188, 221 (2016). https://doi.org/10.1007/s10661-016-5227-1

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Keywords

  • Mobile phones
  • Health effects
  • Radio frequency energy
  • Cancer