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Human adenovirus spread, rainfalls, and the occurrence of gastroenteritis cases in a Brazilian basin

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Abstract

Climate variables may interfere with the environmental persistence and spread of pathogenic microorganisms. This study aimed to investigate the occurrence of human adenovirus (HAdV) and total and thermotolerant coliforms in treated and untreated water and report gastroenteritis cases in seven cities located in the hydrographic basin of the Sinos River (HBSR), Southern Brazil. The data on water quality from samples collected at catchment areas of HBSR from March to December 2011 were compared with precipitation records, virus detection rates and viral loads, and information on enteric diseases among residents of the region. There was a marked increase in precipitation intensity in April, July, and August and a decrease in May and November. The number of HAdV genome copies (gc) in untreated water ranged from 2.1 × 108 gc/L in June to 7.8 × 101 gc/L in December, and in treated water, from 6.3 × 104 gc/L in September to 4.1 × 101 gc/L in November. The most probable number (MPN) of total coliforms ranged from 5 × 101 MPN/100 mL in December to 2.4 × 105 MPN/100 mL in July, and thermotolerant coliforms ranged from 1 × 101 MPN/100 mL in August to 6.9 × 104 MPN/100 mL in July. A total of 79 hospital admissions due to gastroenteritis were registered in the cities studied. The results for coliforms in untreated water demonstrate deficits in sanitation and wastewater treatment. These findings also indicate a possible relationship between the occurrence of rainfalls after dry periods and an increase in the number of gastroenteritis cases and in HAdV load quantified in surface water collected for conventional potabilization.

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References

  • Aslan, A., Xagoraki, I., Simmons, F. J., Rose, J. B., & Dorevitch, S. (2011). Occurrence of adenovirus and other enteric viruses in limited contact freshwater recreational areas and bathing waters. Journal of Applied Microbiology. doi:10.1111/j.1365-2672.2011.05130.

    Google Scholar 

  • Borchardt, M. A., Bertz, P. D., Spencer, S. K., & Battigelli, D. A. (2003). Incidence of enteric viruses in groundwater from household wells in Wisconsin. Applied and Environmental Microbiology, 69(2), 1172–1180.

    Article  CAS  Google Scholar 

  • Bosch, A. (1998). Human enteric viruses in water environment: a minireview. International Microbiology, 1(3), 191–196.

    CAS  Google Scholar 

  • Cash, B. A., Rodó, X., & Kinter, J. L. (2008). Links between tropical Pacific SST and cholera incidence in Bangladesh: role of the eastern and central tropical Pacific. Journal of Climate. doi:10.1175/2007JCLI2001.1.

    Google Scholar 

  • Cunha, A.C., Cunha, H.F.A., Souza, J.A. & Nazaré, A.S. (2005). Monitoramento de Águas Superficiais em Rios Estuarinos do Estado do Amapá sob Poluição Microbiológica. Boletim Museu Paraense Emílio Goeldi, série Ciências Naturais, 1(1), 191–199.

  • Curriero, F., Patz, J., Rose, J., & Lele, S. (2001). The association between extreme precipitation and waterborne disease outbreaks in the United States, 1948–1994. American Journal of Public Health, 91(8), 1194–1199.

    Article  CAS  Google Scholar 

  • Ebi, K. L., Mills, D. M., Smith, J. B., & Grambsch, A. (2006). Climate change and human health impacts in the United States: an update on the results of the U.S. National Assessment. Environmental Health Perspectives. doi:10.1289/ehp.8880.

    Google Scholar 

  • Ebi, K. L., & Paulson, J. A. (2007). Climate change and children. Pediatric of Clinics North American, 54(2), 213–226.

    Article  Google Scholar 

  • Figueiredo, J. A., Drumm, E., Rodrigues, M. A., & Spilki, F. R. (2010). The Rio dos Sinos watershed: an economic and social space and its interface with environmental status. Brazilian Journal of Biology, 70, 131–1136.

    Google Scholar 

  • Fong, T. T., & Lipp, E. K. (2005). Enteric viruses of humans and animals in aquatic environments: health risks, detection, and potential water quality assessment tools. Microbiology and molecular biology reviews: MMBR. doi:10.1128/MMBR.69.2.357-371.2005.

    Google Scholar 

  • Gaffield, S. J., Goo, R. L., Richards, L. A., & Jackson, R. J. (2003). Public health effects of inadequately managed storm water runoff. American Journal of Public Health, 93(9), 1527–1533.

    Article  Google Scholar 

  • Gofti-Laroche, L., Gratacap-Cavallier, B., Genoulaz, O., Joret, J.C., Harteman, P.H,. et al. (2001). A new analytical tool to assess health risks associated with the virological quality of drinking water (EMIRA study). Water Science & Technology, 43(2):39–48.

    CAS  Google Scholar 

  • Griffin, S., Stgelais, C., Owsianka, A. M., Patel, A. H., Rowlands, D., et al. (2008). Genotype-dependent sensitivity of hepatitis C virus to inhibitors of the p7 ion channel. Hepatology. doi:10.1002/hep.22555.

    Google Scholar 

  • Hata, A., Hiroyuki, K., Keisuke, K., Shoichi, S., Ikuro, K., et al. (2014). Effects of rainfall events on the occurrence and detection efficiency of viruses in river water impacted by combined sewer overflows. Science of the Total Environment. doi:10.1016/j.scitotenv.2013.08.093.

    Google Scholar 

  • Horman, A., Rimhannen-Finne, R., Maunula, L., Von Bonsdorff, C. H., Torvela, N., et al. (2004). Campylobacter spp., Giardia spp., Cryptosporidium spp., noroviruses, and indicator organisms in surface water in southwestern Finland, 2000 e 2001. Applied and Environmental Microbiology, 70(1), 87–95.

    Article  Google Scholar 

  • Hunter, P. R. (2003). Climate change and waterborne and vector-borne disease. Journal of Applied Microbiology, 94(Suppl), 37S–46S.

    Article  Google Scholar 

  • Jiang, S. C., & Chu, W. (2004). PCR detection of pathogenic viruses in southern California urban rivers. Journal of Applied Microbiology, 97(1), 17–28.

    Article  CAS  Google Scholar 

  • Karl, T. R., & Trenberth, K. E. (2003). Modern global climate change. Science;. doi:10.1126/science.1090228.

    Google Scholar 

  • Katayama, H., Shimasaki, A., & Ohgaki, S. (2002). Development of a virus concentration method and its application to detection of enterovirus and Norwalk virus from coastal seawater. Applied and Environmental Microbiology. doi:10.1128/AEM.68.3.1033-1039.2002.

    Google Scholar 

  • Kiska, D. L. (2000). Global climate change: an infectious disease perspective. Clinical Microbiology Newsletter, 22(11), 81–86.

    Article  Google Scholar 

  • Lenaerts, L., De Clercq, E., & Naesens, L. (2008). Clinical features and treatment of adenovirus infections. Reviews in Medical Virology. doi:10.1002/rmv.589.

    Google Scholar 

  • Rijal, G., Petropoulou, C., Tolson, J. K., Deflaun, M., Gerba, C., et al. (2009). Dry and wet weather microbial characterization of the Chicago area waterway system. Water Science & Technology. doi:10.2166/wst.2009.598.

    Google Scholar 

  • Selvakumar, A., & Borst, M. (2006). Variation of microorganism concentrations in urban stormwater runoff with land use and seasons. Journal of Water and Health, 4(1), 109–124.

    Google Scholar 

  • Sidhu, J. P. S., Hodgers, L., Ahmed, W., Chong, M. N., & Toze, S. (2012). Prevalence of human pathogens and indicators in storm water runoff in Brisbane, Australia. Water Research. doi:10.1016/j.watres.2012.03.012.

    Google Scholar 

  • Staggemeier, R,. Bortoluzzi, M., da Silva Heck, T.M., da Luz, R.B., Fabres, R.B., et al. (2015). Animal and human enteric viruses in water and sediment samples from dairy farms. Agricultural Water Management, doi:10.1016/j.agwat.2015.01.010.

    Google Scholar 

  • Tavares, T. M., Cardoso, D. D. P., & de Brito, W. M. E. D. (2005). Vírus entéricos veiculados por água: aspectos microbiológicos e de controle de qualidade da água. Revista de Patologia Tropical, 34, 85–104.

    Google Scholar 

  • Van Heerden, J., Ehlers, M.M., Van, Z.Y.L., W.B. & Grabow, H.O.K. (2003). Incidence of adenoviruses in raw and treated water. Water Research, 37(15), 3704–3708.

  • Vecchia, A. D., Fleck, J. D., Comerlato, J., Kluge, M., Bergamaschi, B., et al. (2012). First description of adenovirus, enterovirus, rotavirus and Torque teno virus in water samples collected from the Arroio Dilúvio, Porto Alegre, Brazil. Brazilian Journal of Biology. doi:10.1590/S1519-69842012000200013.

    Google Scholar 

  • Vecchia, A. D., Rigotto, C., Staggemeier, R., Soliman, M. C., Souza, F. G., & Henzel, A. (2015). Surface water quality in the Sinos River basin, in Southern Brazil: tracking microbiological contamination and correlation with physicochemical parameters. Environmental Science and Pollution Research International. doi:10.1007/s11356-015-4175-6.

    Google Scholar 

  • Vieira, C. B., Mendes, A. C. O., Guimarães, F. R., Fumian, T. M., Leite, J. P. G., et al. (2012). Detection of enteric viruses in recreational waters of an urban lagoon in the city of Rio de Janeiro, Brazil. Memórias Instituto Oswaldo Cruz, 107(6), 778–784.

    Article  CAS  Google Scholar 

  • Victoria, M., Fumian, T. M., Rocha, M. S., Dalmao, F., Leite, J. P., et al. (2014). Gastroenteric virus dissemination and influence of rainfall events in urban beaches in Brazil. Journal of Applied Microbiology. doi:10.1111/jam.12592.

    Google Scholar 

  • Wold, W. S. M., & Horwitz, M. S. (2007). Adenoviruses. In D. M. Knipe, & P. M. Howley (Eds.), Fields Virology (5th ed., ). Philadelphia: Lippincott Willians and Wilkins.

    Google Scholar 

  • Wolf, S., Hewitt, J., & Greening, G. E. (2010). Viral multiplex quantitative PCR assays for tracking sources of fecal contamination. Applied Environmental and Microbiology. doi:10.1128/AEM.022.

    Google Scholar 

  • World Health Organization – WHO (2008). Guidelines for drinking-water quality—recommendations (3rd ed., ). Geneva.

Download references

Conflict of interest

The authors declare that they have no competing interests.

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Authors and Affiliations

  1. Unidade Acadêmica de Ciências da Saúde – Coordenação do Curso de Biomedicina, Bloco S, Universidade do Extremo Sul Catarinense – UNESC, Criciúma, Brazil

    Manoela Tressoldi Rodrigues

  2. Laboratório de Microbiologia Molecular, Instituto de Ciências da Saúde, Universidade Feevale, Prédio Vermelho 2° Andar, Sala 205 RS 239, no 2755, Vila Nova, Novo Hamburgo, RS, CEP 93352-000, Brazil

    Andréia Henzel, Rodrigo Staggemeier, Caroline Rigotto, Larissa Heinzelmann, Carlos Augusto do Nascimento & Fernando Rosado Spilki

  3. Instituto de Ciências Aplicadas, Universidade Feevale, Novo Hamburgo, RS, Brazil

    Daniela Muller de Quevedo

Authors
  1. Manoela Tressoldi Rodrigues
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  2. Andréia Henzel
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  3. Rodrigo Staggemeier
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  4. Daniela Muller de Quevedo
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  5. Caroline Rigotto
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  6. Larissa Heinzelmann
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  7. Carlos Augusto do Nascimento
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  8. Fernando Rosado Spilki
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Correspondence to Andréia Henzel.

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This study was funded by state funding agency Fundação de Amparo à Pesquisa do Rio Grande do Sul (FAPERGS) [grant number 10/1339–2]. Fernando Rosado Spilki is a CNPq research fellow.

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Rodrigues, M.T., Henzel, A., Staggemeier, R. et al. Human adenovirus spread, rainfalls, and the occurrence of gastroenteritis cases in a Brazilian basin. Environ Monit Assess 187, 720 (2015). https://doi.org/10.1007/s10661-015-4917-4

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  • DOI: https://doi.org/10.1007/s10661-015-4917-4

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