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Utility of cefixime as a complexing reagent for the determination of Ni(II) in synthetic mixture and water samples

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Abstract

A simple, sensitive, and accurate UV spectrophotometric method has been developed for the determination of nickel in synthetic mixture and water samples. The method is based on the complexation reaction of nickel ion with cefixime, thus leading to the formation of Ni–cefixime complex in ethanol-distilled water medium at room temperature. The complex showed the maximum absorption wavelength at 332 nm. Beer’s law is obeyed in the working concentration range of 0.447–4.019 μg mL−1 with apparent molar absorptivity of 7.314 × 103 L mol−1 cm−1 and Sandell’s sensitivity of 0.008 μg/cm2/0.001 absorbance unit. The limits of detection and quantitation for the proposed method are 0.016 and 0.054 μg mL−1, respectively. The factors such as cefixime concentration and solvent affecting the complexation reaction were carefully studied and optimized. The method is validated as per the International Conference on Harmonisation guideline. The method is successfully applied to the determination of Ni(II) in synthetic mixture and wadi water samples collected from Al Rustaq. The same water samples are also analyzed by atomic absorption spectrophotometry. Both methods determined the amount of Ni(II) in water sample and found to be approximately the same.

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References

  • Ahmadi, F., Mohammadi, A. K., Heydari, S., Mirzazadeh, M., & Malekpour, E. (2008). Micelle mediated methodology for the determination of heavy metals in real samples by flame atomic absorption spectrometry. Jordan Journal of Chemistry, 3, 77–86.

    CAS  Google Scholar 

  • Albertus, F., Cladera, A., Becerra, E., & Cerda, V. (2001). A robust multi-syringe system for process flow analysis. Part3. Time based injection applied to the spectrophotometric determination of Ni(II) and iron speciation. Analyst, 126, 903.

    Article  CAS  Google Scholar 

  • Buzica, D., Gerboles, M., Borowiak, A., Trincherini, P., Passarella, R., & Pedroni, V. (2006). Comparison of voltammetry and inductively coupled plasma-mass spectrometry for the determination of heavy metals in PM10 airborne particulate matter. Atmospheric Environment, 40, 4703–4710.

    Article  CAS  Google Scholar 

  • Czegan, D. A. C., & Hoover, D. K. (2012). UV–visible spectrometers: versatile instruments across the chemistry curriculum. Journal of Chemical Education, 89, 304–309.

    Article  CAS  Google Scholar 

  • Dipak, J., Garole, A. D., & Sawant, A. D. (2005). Extractive spectrophotometric determination of Ni(II) using 4-methyl 2,3-pentanedione dioxime. Journal of Scientific and Industrial Research, 64, 581.

    Google Scholar 

  • Garcia-Otero, N., Teijeiro-Valino, C., Otero-Romani, J., Pena-Vazquez, E., Moreda-Pineiro, A., & Bemejo-Barrera, P. (2009). On-line ionic imprinted polymer selective solid-phase extraction of nickel and lead from seawater and their determination by inductively coupled plasma-optical emission spectrometry. Analytical and Bioanalytical Chemistry, 395, 1107–1115.

    Article  CAS  Google Scholar 

  • Garole, D. J., & Sawant, A. D. (2005). Extractive spectrophotometric determination of nickel (II) using 4-methyl 2,3-pentanedione dioxime. Journal of Scientific and Industrial Research, 64, 581.

    CAS  Google Scholar 

  • Gazda, D. B., Fritz, J. S., & Porter, M. D. (2004). Determination of Ni(II) as the nickel dimethylglyoxime complex using colorimetric solid phase extraction. Analytica Chimica Acta, 508, 53–59.

    Article  CAS  Google Scholar 

  • Gholivand, M. B., Bahrami, S., Abbasi, S., & Sohrabi, A. (2008). Simultaneous determination of nickel and cadmium by adsorptive stripping voltammetry. Electroanalysis, 20, 1367–1373.

    Article  CAS  Google Scholar 

  • Hartmann, C., Smeyers-Verbeke, J., Pinninckx, W., Heyden, Y. V., Vankeerberghen, P., & Massart, D. L. (1995). Reappraisal of hypothesis testing for method validation: detection of systematic error by comparing the means of two methods or of two laboratories. Analytical Chemistry, 67, 4491.

    Article  CAS  Google Scholar 

  • Hashem, E. Y., Abu-Bakr, M. S., & Hussain, S. M. (2003). Interaction of nickel with 4-(2′-benzothiazolylazo) salicylic acid (BTAS) and simultaneous first-derivative spectrophotometric determination of nickel(II) and iron(III). Spectrochimica Acta A, 59, 761–769.

    Article  CAS  Google Scholar 

  • Hu, Q., Yang, G., & Yang, J. (2002). Study of determination of Fe, Co, Ni, Cu, Zn, and Mn in drinking water by solid-phase extraction and RP-HPLC with 2-(2-quinolinylazo)-5-diethylaminophenol as precolumn derivatizing reagent. Journal of Environmental Monitoring, 4, 956.

    Article  CAS  Google Scholar 

  • International Conference on Harmonisation, Food and Drug Administration, Rockville, MD, USA. (1995). ICH harmonised tripartite guideline—text on validation of analytical procedures. Federal Register, 60, 11260.

    Google Scholar 

  • Kabil, M. A., Ghazy, S. E., Lasheen, M. R., Shallaby, M. A., & Amar, N. S. (1996). Spectrophotometric and atomic absorption determination of Ni(II) in fresh and sea waters after preconcentration by flotation. Fresenius Journal of Analytical Chemistry, 354, 371.

    CAS  Google Scholar 

  • Khani, R., & Shemirani, F. (2010). Determination of trace levels of nickel and manganese in soil, vegetable, and water. Clean—Soil, Air, Water, 38, 1177–1183.

    Article  CAS  Google Scholar 

  • Likussar, W., & Boltz, D. F. (1971). Spectrophotometric determination of extraction constants for certain metal 1-pyrrolidinecarbodithioates. Analytical Chemistry, 43, 1265.

    Article  CAS  Google Scholar 

  • Magni, D. M., Olivieri, A. C., & Bonivardi, A. L. (2005). Artificial neural networks study of the catalytic reduction of resazurin stopped flow injection kinetic spectrophotometric determination of Cu(II) and Ni(II). Analytica Chimica Acta, 528, 275.

    Article  CAS  Google Scholar 

  • Malik, A. K., Kaul, K. N., & Lark, B. S. (2000). Spectrophotometric determination of Co(II), Ni(II), Cu(II), Pd(II), Ru(III), and Mo(VI) using sodium isoamylxanthate in presence of surfactants. Turkish Journal of Chemistry, 25, 99–105.

    Google Scholar 

  • Mendham, J., Denney, R. C., Barnes, J. D., & Thomas, M. (2002). Statistics: Introduction to chemometrics. In: Vogel's Textbook of Quantitative Chemical Analysis (6th edition). Singapore: Pearson Education, p. 137.

  • Miller, J. C., & Miller, J. N. (1993). Errors in instrumental analysis; regression and correlation. In: Statistics for Analytical Chemistry (3rd edition). London: Horwood, p. 115.

  • Nakamoto, K. (2009). Applications in coordination, organometallic and bioinorganic chemistry. In: Infrared and Raman spectra of Inorganic and coordination compounds (6th edition). USA: John Wiley and Sons Inc., Hoboken, p. 17.

  • Nalimov, V. V. (1963). The application of mathematical statistics to chemical analysis (p. 167). Oxford: Pergamon.

    Google Scholar 

  • Ozturk, B. D., Filik, H., & Tutem, E. (2000). Simultaneous spectrophotometric determination of Co(II), and Ni(II) by dithiozone without extraction. Talanta, 53, 263–269.

    Article  CAS  Google Scholar 

  • Shar, G. A., & Soomro, G. A. (2006). Spectrophotometric determination of cobalt, nickel, copper with 1-(2 pyridylazo)-2-naphthol in micellar medium. Journal of the Chemical Society of Pakistan, 28, 331.

    CAS  Google Scholar 

  • Sun, Z., Liang, P., & Ding, Q. (2006). Determination of trace nickel in water samples by cloud point extraction preconcentration coupled with graphite furnace atomic absorption spectrometry. Journal of Hazardous Materials, 137, 943–946.

    Article  CAS  Google Scholar 

  • Suresh, K. K., Prabhakaras, R., Kishnaiah, L., Yayaraj, B., & Chiranjeevi, P. (2004). Determination of Ni(II) in alloys and plant leaves with salicylaldehyde 5-oxobutanoylhydrazone by spectrophotometry. Analytical Sciences, 20, 951–953.

    Article  Google Scholar 

  • Taher, M. A., Dehzoei, A. M., & Puri, B. K. (1998). Derivative UV–visible spectrophotometric determination of Ni in alloys and biological samples after preconcentration with the ion pair of 2-nitroso-1-naphthol-4-sulfonic acid and tetradecyldimethylbenzylammonium chloride onto microcrystalline naphthalene or by a column method. Analytica Chimica Acta, 367, 55–61.

    Article  Google Scholar 

  • World Health Organization. (2000). Air quality guidelines for Europe, WHO regional publications, European service, no. 91 (2nd ed.). Copenhagen: WHO Regional Office for Europe.

    Google Scholar 

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Acknowledgments

The authors are grateful to Aligarh Muslim University, Aligarh, India and Ministry of ManPower (Higher College of Technology) Muscat, Sultanate of Oman for facilities. The authors wish to express their gratitude to M/s National Pharmaceutical Industries Company, Oman for providing the gift sample of pure cefixime.

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Authors and Affiliations

  1. Department of Applied Sciences, Chemistry Section, Higher College of Technology, Al-Khuwair-133, P. O. Box 74, Muscat, Sultanate of Oman

    Syed Najmul Hejaz Azmi, Bashir Iqbal, Reem Saif Al Khanbashi & Nadia Humaid Al Hamhami

  2. Department of Chemistry, Aligarh Muslim University, Aligarh, 202002, Uttar Pradesh, India

    Nafisur Rahman

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  1. Syed Najmul Hejaz Azmi
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  2. Bashir Iqbal
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  3. Reem Saif Al Khanbashi
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  4. Nadia Humaid Al Hamhami
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  5. Nafisur Rahman
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Correspondence to Syed Najmul Hejaz Azmi.

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Azmi, S.N.H., Iqbal, B., Al Khanbashi, R.S. et al. Utility of cefixime as a complexing reagent for the determination of Ni(II) in synthetic mixture and water samples. Environ Monit Assess 185, 4647–4657 (2013). https://doi.org/10.1007/s10661-012-2894-4

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