In the developing world, environmental chemical exposures due to hazardous waste sites are poorly documented. We describe the approach taken by the Blacksmith Institute's Toxic Sites Identification Program in documenting environmental chemical exposures due to hazardous waste sites globally, identifying sites of concern and quantifying pathways, populations, and severity of exposure. A network of local environmental investigators was identified and trained to conduct hazardous waste site investigations and assessments. To date, 2,095 contaminated sites have been identified within 47 countries having an estimated population at risk of 71,500,000. Trained researchers and investigators have visited 1,400 of those sites. Heavy metals are the leading primary exposures, with water supply and ambient air being the primary routes of exposure. Even though chemical production has occurred largely in the developed world to date, many hazardous waste sites in the developing world pose significant hazards to the health of large portions of the population. Further research is needed to quantify potential health and economic consequences and identify cost-effective approaches to remediation.
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Toxic Sites Identification Program
Hazard ranking system
Initial site screening
Short Message Service
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US Environmental Protection Agency
Chen, A., Dietrich, K. N., Huo, X., & Ho, S-m. (2011). Developmental neurotoxicants in E-Waste: an emerging health concern. Environmental Health Perspectives, 119, 431–438.
Cifuentes, E., & Rodriguez, S. (2005). Urban sprawl, water insecurity, and enteric diseases in children from Mexico City. EcoHealth, 2(1), 70–75.
Ela, W. P., Sedlak, D. L., Barlaz, M. A., Henry, H. F., Muir, D. C., Swackhamer, D. L., et al. (2011). Toward Identifying the next generation of superfund and hazardous waste site contaminants. Environmental Health Perspectives, 119, 6–10.
Engel, S. M., Wetmur, J., Chen, J., Zhu, C., Barr, D. B., Canfield, R. L., et al. (2011). Prenatal exposure to organophosphates, paraoxonase 1, and cognitive development in childhood. Environmental Health Perspectives, 119, 1182–1188.
Fewtrell, L. J., Prüss-Üstün, A., Landrigan, P., & Ayuso-Mateos, J. L. (2004). Estimating the global burden of disease of mild mental retardation and cardiovascular diseases from environmental lead exposure. Environmental Research, 94(2), 120–133.
Fewtrell, L. J., Fuge, R., & Kay, D. (2005). An estimation of the global burden of disease due to skin lesions caused by arsenic in drinking water. Journal of Water and Health, 3(2), 101–107.
Johnson, B. L., Hicks, H. E., Cibulas, W., Faroon, O., Ashizawa, A. E., De Rosa, C. T. (2008). Public Health Implications of Exposure to Polychlorinated Biphenyls (PCBs). Available at: http://www.atsdr.cdc.gov/dt/pcb007.html#ABSTRACT. Accessed 11 October 2011.
Kumar, R., & Joseph, A. E. (2006). Air pollution concentrations of PM 2.5, PM 10 and NO 2 at ambient and kerbsite and their correlation in Metro City-Mumbai. Environmental Monitoring and Assessment, 119(1), 191–199.
Kushner, L. M. (1986). Hazard ranking system issue analysis: sites with unknown waste quantity, report MTR-86W83. McLean: Mitre Corporation.
Laden, F., Neas, L. M., Dockery, D. W., & Schwartz, J. (2000). Association of Fine Particulate Matter from Different Sources with Daily Mortality in Six U.S. Cities. Environmental Health Perspectives, 108, 941–947.
Lanphear, B. P., Hornung, R., Khoury, J., Yolton, K., Baghurst, P., Bellinger, D. C., et al. (2005). Low-level environmental lead exposure and children’s intellectual function: an international pooled analysis. Environmental Health Perspectives, 113, 894–899.
Mølbak, K., Højlyng, N., Jepsen, S., & Gaarslev, K. (2009). Bacterial contamination of stored water and stored food: a potential source of diarrhoeal disease in West Africa. Epidemiology and Infection, 102(02), 309–316.
National Research Council (NRC). (1994). Ranking hazardous-waste sites for remedial action. Washington: National Academy Press.
Perera, F., Wang, S., Vishnevetsky, J., Zhang, B., Cole, K. J., Tang, V., Rauh, D., Philips., D. H. (2012). PAH/aromatic DNA adducts in cord blood and behavior scores in New York City Children. Environmental Health Perspectives (in press).
Prüss-Ustün, A., Vickers, C., Haefliger, P., & Bertollini, R. (2011). Knowns and unknowns on burden of disease due to chemicals: a systematic review. Environmental Health, 10(9).
Raga, G. B., Baumgardner, D., Castro, T., Martinez-Arroyo, A., & Navarro-Gonzalez, R. (2001). Mexico City air quality: a qualitative review of gas and aerosol measurements (1960–2000). Atmospheric Environment, 35(23), 4041–4058.
Rio-Chivardi, J. M. D., Berber, A., Sienra-Monge, J. J. L., Rosas-Vargas, M. A., Baeza-Bacab, M., et al. (2006). Asthma prevalence in children living in north Mexico City and a comparison with other Latin American cities and world regions. Allergy and Asthma Proceedings, 27(4), 334–340.
Sacks, J. D., Stanek, L. W., Luben, T. J., Johns, D. O., Buckley, B. J., Brown, J. S., et al. (2011). Particulate matter–induced health effects: who is susceptible? Environmental Health Perspectives, 119, 446–454.
Schwartz, J. (1994a). Societal benefits of reducing lead exposure. Environmental Progress, 66(1).
Schwartz, J. (1994b). Low-level lead exposure and children's IQ: a meta-analysis and search for a threshold. Environmental Research, 65(1), 42–55.
Srivastava, A., & Kumar, R. (2002). Economic valuation of health impacts of air pollution in Mumbai. Environmental Monitoring and Assessment, 75(2), 135–143.
The World Bank. (2010). Country classifications. Available at: http://data.worldbank.org/about/country-classifications. Accessed 22 June 2010
Tornheim, J., Morland, K., Landrigan, P., & Cifuentes, E. (2007). Association between type of primary water source and prevalence of diarrheal disease in Bolivia. Epidemiology, 18(5), S103–S104.
US Environmental Protection Agency. (2011). Superfund: Basic Information. http://www.epa.gov/superfund/about.htm. (Accessed 3 October 2011).
Yáñez, L., Ortiz, D., Calderón, J., Batres, L., Carrizales, L., Mejía, J., et al. (2002). Overview of human health and chemical mixtures: problems facing developing countries. Environmental Health Perspectives, 110, 901–909.
Zaragoza, L. J. (1990). Cutoff Score Analysis for the Revised Hazard Ranking System (HRS) Docket, U.S. Environmental. Protection Agency Memo to HRS Docket. 105NCP-HRS-18-18. U.S. Environmental Protection Agency, Washington, DC.
The Toxic Sites Identification Program is supported by the European Commission, the United Nations Industrial Development Organization, Green Cross Switzerland, and the Asian Development Bank. Dr. Caravanos serves on the Technical Advisory Board to the Blacksmith Institute. Dr. Philip Landrigan serves without compensation on the Blacksmith Advisory Board, as well as its Technical Advisory Board.
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Ericson, B., Caravanos, J., Chatham-Stephens, K. et al. Approaches to systematic assessment of environmental exposures posed at hazardous waste sites in the developing world: the Toxic Sites Identification Program. Environ Monit Assess 185, 1755–1766 (2013). https://doi.org/10.1007/s10661-012-2665-2
- Hazardous waste sites
- Developing world
- Risk assessment
- Children's health