Environmental Monitoring and Assessment

, Volume 185, Issue 2, pp 1755–1766 | Cite as

Approaches to systematic assessment of environmental exposures posed at hazardous waste sites in the developing world: the Toxic Sites Identification Program

  • Bret Ericson
  • Jack Caravanos
  • Kevin Chatham-StephensEmail author
  • Philip Landrigan
  • Richard Fuller


In the developing world, environmental chemical exposures due to hazardous waste sites are poorly documented. We describe the approach taken by the Blacksmith Institute's Toxic Sites Identification Program in documenting environmental chemical exposures due to hazardous waste sites globally, identifying sites of concern and quantifying pathways, populations, and severity of exposure. A network of local environmental investigators was identified and trained to conduct hazardous waste site investigations and assessments. To date, 2,095 contaminated sites have been identified within 47 countries having an estimated population at risk of 71,500,000. Trained researchers and investigators have visited 1,400 of those sites. Heavy metals are the leading primary exposures, with water supply and ambient air being the primary routes of exposure. Even though chemical production has occurred largely in the developed world to date, many hazardous waste sites in the developing world pose significant hazards to the health of large portions of the population. Further research is needed to quantify potential health and economic consequences and identify cost-effective approaches to remediation.


Hazardous waste sites Developing world Risk assessment Children's health 



Blacksmith Institute


Toxic Sites Identification Program


Hazard ranking system


Initial site screening


Intellectual quotient


Key pollutant


Nongovernmental organization


Short Message Service


US Environmental Protection Agency



The Toxic Sites Identification Program is supported by the European Commission, the United Nations Industrial Development Organization, Green Cross Switzerland, and the Asian Development Bank. Dr. Caravanos serves on the Technical Advisory Board to the Blacksmith Institute. Dr. Philip Landrigan serves without compensation on the Blacksmith Advisory Board, as well as its Technical Advisory Board.


  1. Chen, A., Dietrich, K. N., Huo, X., & Ho, S-m. (2011). Developmental neurotoxicants in E-Waste: an emerging health concern. Environmental Health Perspectives, 119, 431–438.CrossRefGoogle Scholar
  2. Cifuentes, E., & Rodriguez, S. (2005). Urban sprawl, water insecurity, and enteric diseases in children from Mexico City. EcoHealth, 2(1), 70–75.CrossRefGoogle Scholar
  3. Ela, W. P., Sedlak, D. L., Barlaz, M. A., Henry, H. F., Muir, D. C., Swackhamer, D. L., et al. (2011). Toward Identifying the next generation of superfund and hazardous waste site contaminants. Environmental Health Perspectives, 119, 6–10.CrossRefGoogle Scholar
  4. Engel, S. M., Wetmur, J., Chen, J., Zhu, C., Barr, D. B., Canfield, R. L., et al. (2011). Prenatal exposure to organophosphates, paraoxonase 1, and cognitive development in childhood. Environmental Health Perspectives, 119, 1182–1188.CrossRefGoogle Scholar
  5. Fewtrell, L. J., Prüss-Üstün, A., Landrigan, P., & Ayuso-Mateos, J. L. (2004). Estimating the global burden of disease of mild mental retardation and cardiovascular diseases from environmental lead exposure. Environmental Research, 94(2), 120–133.CrossRefGoogle Scholar
  6. Fewtrell, L. J., Fuge, R., & Kay, D. (2005). An estimation of the global burden of disease due to skin lesions caused by arsenic in drinking water. Journal of Water and Health, 3(2), 101–107.Google Scholar
  7. Johnson, B. L., Hicks, H. E., Cibulas, W., Faroon, O., Ashizawa, A. E., De Rosa, C. T. (2008). Public Health Implications of Exposure to Polychlorinated Biphenyls (PCBs). Available at: Accessed 11 October 2011.
  8. Kumar, R., & Joseph, A. E. (2006). Air pollution concentrations of PM 2.5, PM 10 and NO 2 at ambient and kerbsite and their correlation in Metro City-Mumbai. Environmental Monitoring and Assessment, 119(1), 191–199.CrossRefGoogle Scholar
  9. Kushner, L. M. (1986). Hazard ranking system issue analysis: sites with unknown waste quantity, report MTR-86W83. McLean: Mitre Corporation.Google Scholar
  10. Laden, F., Neas, L. M., Dockery, D. W., & Schwartz, J. (2000). Association of Fine Particulate Matter from Different Sources with Daily Mortality in Six U.S. Cities. Environmental Health Perspectives, 108, 941–947.CrossRefGoogle Scholar
  11. Lanphear, B. P., Hornung, R., Khoury, J., Yolton, K., Baghurst, P., Bellinger, D. C., et al. (2005). Low-level environmental lead exposure and children’s intellectual function: an international pooled analysis. Environmental Health Perspectives, 113, 894–899.CrossRefGoogle Scholar
  12. Mølbak, K., Højlyng, N., Jepsen, S., & Gaarslev, K. (2009). Bacterial contamination of stored water and stored food: a potential source of diarrhoeal disease in West Africa. Epidemiology and Infection, 102(02), 309–316.CrossRefGoogle Scholar
  13. National Research Council (NRC). (1994). Ranking hazardous-waste sites for remedial action. Washington: National Academy Press.Google Scholar
  14. Perera, F., Wang, S., Vishnevetsky, J., Zhang, B., Cole, K. J., Tang, V., Rauh, D., Philips., D. H. (2012). PAH/aromatic DNA adducts in cord blood and behavior scores in New York City Children. Environmental Health Perspectives (in press).Google Scholar
  15. Prüss-Ustün, A., Vickers, C., Haefliger, P., & Bertollini, R. (2011). Knowns and unknowns on burden of disease due to chemicals: a systematic review. Environmental Health, 10(9).Google Scholar
  16. Raga, G. B., Baumgardner, D., Castro, T., Martinez-Arroyo, A., & Navarro-Gonzalez, R. (2001). Mexico City air quality: a qualitative review of gas and aerosol measurements (1960–2000). Atmospheric Environment, 35(23), 4041–4058.CrossRefGoogle Scholar
  17. Rio-Chivardi, J. M. D., Berber, A., Sienra-Monge, J. J. L., Rosas-Vargas, M. A., Baeza-Bacab, M., et al. (2006). Asthma prevalence in children living in north Mexico City and a comparison with other Latin American cities and world regions. Allergy and Asthma Proceedings, 27(4), 334–340.CrossRefGoogle Scholar
  18. Sacks, J. D., Stanek, L. W., Luben, T. J., Johns, D. O., Buckley, B. J., Brown, J. S., et al. (2011). Particulate matter–induced health effects: who is susceptible? Environmental Health Perspectives, 119, 446–454.CrossRefGoogle Scholar
  19. Schwartz, J. (1994a). Societal benefits of reducing lead exposure. Environmental Progress, 66(1).Google Scholar
  20. Schwartz, J. (1994b). Low-level lead exposure and children's IQ: a meta-analysis and search for a threshold. Environmental Research, 65(1), 42–55.CrossRefGoogle Scholar
  21. Srivastava, A., & Kumar, R. (2002). Economic valuation of health impacts of air pollution in Mumbai. Environmental Monitoring and Assessment, 75(2), 135–143.CrossRefGoogle Scholar
  22. The World Bank. (2010). Country classifications. Available at: Accessed 22 June 2010
  23. Tornheim, J., Morland, K., Landrigan, P., & Cifuentes, E. (2007). Association between type of primary water source and prevalence of diarrheal disease in Bolivia. Epidemiology, 18(5), S103–S104.Google Scholar
  24. US Environmental Protection Agency. (2011). Superfund: Basic Information. (Accessed 3 October 2011).
  25. Yáñez, L., Ortiz, D., Calderón, J., Batres, L., Carrizales, L., Mejía, J., et al. (2002). Overview of human health and chemical mixtures: problems facing developing countries. Environmental Health Perspectives, 110, 901–909.CrossRefGoogle Scholar
  26. Zaragoza, L. J. (1990). Cutoff Score Analysis for the Revised Hazard Ranking System (HRS) Docket, U.S. Environmental. Protection Agency Memo to HRS Docket. 105NCP-HRS-18-18. U.S. Environmental Protection Agency, Washington, DC.Google Scholar

Copyright information

© Springer Science+Business Media B.V. 2012

Authors and Affiliations

  • Bret Ericson
    • 4
  • Jack Caravanos
    • 3
    • 4
  • Kevin Chatham-Stephens
    • 1
    Email author
  • Philip Landrigan
    • 1
    • 2
  • Richard Fuller
    • 4
  1. 1.Department of Preventive MedicineMount Sinai School of MedicineNew YorkUSA
  2. 2.Department of PediatricsMount Sinai School of MedicineNew YorkUSA
  3. 3.School of Public Health at Hunter CollegeCity University of New YorkNew YorkUSA
  4. 4.Blacksmith InstituteNew YorkUSA

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