Abstract
Anupgarh is the most fertile area of Rajasthan state where a variety of seasonal crops are grown. The availability of three manmade canals has enhanced the agricultural activities in this area. The farmers use huge amounts of pesticides to increase the crop productivity. Exposure of humans to these hazardous chemicals occurs directly in the fields and indirectly due to consumption of contaminated diet, or by inhalation or by dermal contact. The organochlorine pesticides are reported to be lipophilic and their presence in human milk and blood has been documented in different parts of the world. Blood and milk samples were collected from lactating women who were divided into four groups on the basis of different living standards viz residence area, dietary habits, working conditions and addiction to tobacco. The level of total organochlorine pesticides in blood ranged from 3.319mg/L—6.253mg/L while in milk samples it ranged from 3.209Mdash;4.608 mg/L. The results are in concurrence with the reports from other countries.
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Ando, M., Saito, H. and Wakesaka, I.: 1985, ‘Transfer of Polychlorinated biphenyls (PCBs) to newborn infants through the placenta and mother's milk’, Arch. Environ. Contam. Toxicol. 14, 51–57.
Bakore, N., John, P. J. and Bhatnagar, P.: 2002, ‘Evaluation of organochlorine insecticide residue levels in locally marketed vegetables of Jaipur city, Rajasthan, India’, J. Environ. Biol. 23(3), 247–252.
Bhatnagar, V. K., Patel, J. S., Variya, M. R., Venkaiha, K., Shah, M. P. and Kashyap, S. K.: 1992, ‘Levels of organochlorine insecticides in human blood from Ahemadabad (Rural) India’, Bull. Environ. Contam. Toxicol. Environ. Contam. Toxicol. 48, 302–307.
Bush, B., Snow, J. and Koblintz, R.: 1984, ‘Polychlorobiphenyl (PCB), P,P'-DDE and hexachlorobenzene in maternal and fetal blood from mothers in upstate New York’, Arch. Environ. Contam. Toxicol. 13, 517–527.
Cajka, T. and Hajslova, J.: 2003, ‘Polychlorinated biphenyls and OCPs in human milk from the locality Prague, Czec Republic: A comparative study’, Bull. Environ. Contam. Toxicol. 70, 913–919.
Charlier, C. and Plomteux, G.: 2002, ‘Environmental chemical pollution and risk of human exposure; the role of organochlorine pesticides’, Ann. Biol. Clin 60, 37–46.
Chengappa, R. and Rajghatta, C.: 1989, ‘Poison in your food’, India Today. June 15th, 74–83.
Cok, I., Bilgili, A., Ozdemir, M., Ozbek, H., Bilgili, N. and Burgaz, S.: 1997, ‘Organochlorine pesticide residues in human breast milk from agricultural regions of Turkey. 1995–1996’, Bull. Environ. Contam. Toxicol. 59, 577–582.
Czaja, K., Ludwicki, J. K., Goralczyk, K. and Strucinski, P.: 1997, ‘Effects of age and number of deliveries on mean concentration of organochlorine compounds inhuman breast milk in Poland’, Bull. Environ. Contam. Toxicol. 59, 407–413.
Dwarka, S., Harrison, D. J., Hoodless, R. A., Lawn, R. E. and Merson, G. H. J.: 1995, ‘Organochlorine compound residues in the United Kingdom, 1989–1991’, Hum. Experim. Toxicol. 14, 451–455.
Falck, F., Ricci, A., Wolff, M. S., Godbold, J. and Deckers, P.: 1992, ‘Pesticides and polychlorinated biphenyl residues in human breast lipids and their relation to breast cancer’, Arch. Environ. Health 47, 143–146.
Harrison, N., Wearne, S., de Gem, M. G. M., Gleadle, A., Startin, J., Thorpe, S., Wright, C., Kelley Robinson, C., White, S., Hardy, D. and Edinburgh, V.: 1998, ‘Time trends in human dietary exposure to PCDDs, PCDFs and PCBs in the UK’, Chemosphere 37, 1657–1670.
Hathi, D.: 1994, ‘Poison in the Palate’, Deccan Herald.
Jacobson, J. L. and Jacobson, S. W. 1993, ‘A 4-year follow up study of children born to consumers of Lake Michigan fish’, J. Great Lakes Res. 19(4), 776–783.
Jacobson, J. L., Fein, G. G., Jacobson, W., Schwartz, P. M. and Dowler, J. K.: 1984, ‘The transfer of polychlorinated biphenyls (PCBs) and polybrominated biphenyls (PBBs) across the human placenta and into maternal milk’, Am. J. Pub. Health 74, 378–379.
John, P. J., Bakore, N. and Bhatnagar, P.: 1995, ‘Evaluation of organochlorine residues in locally marketed egg, meat and fish samples from Jaipur city, Rajasthan. Abstracts’, in: Proceedings of 16th Annual session of Academy of Environmental Biology, held at Hyderabad.
John, P. J., Bakore, N. and Bhatnagar, P.: 2001, ‘Assessment of organochlorine pesticide residue levels in dairy milk and buffalo milk from Jaipur city, Rajasthan, India’, Environ. Intern. 26, 231–236.
Kalara, R. L. and Chawala, R. P.: 1981, ‘Occurrence of DDT and BHC residues in human milk in India’, Experentia 37, 404–405.
Kanja, L. W., Skaare, J. U., Ojwang, S. B. O. and Maitai, C. K.: 1992, ‘A comparison of organochlorinated pesticide residues in maternal adipose tissue, maternal blood, cord blood and human milk from mother/infant pairs’, Arch. Environ. Contam. Toxicol. 22, 21–24.
Kashyap, R., Iyer, I. R. and Singh, M. M.: 1994, ‘Evaluation of daily dietary intake of DDT and BHC in India, Ahemadabad’, Arch. Environ. Health 49(1), 63–66.
Kathpal,T. S., Singh, G., Yadav, G. S., Dhankar, J. S. and Singh, A.: 1992, ‘Monitoring of milk and milk products for DDT and HCH contamination’, Pestic. Res. J. 4(2), 123–131.
Laug, E. P., Kunze, F. M. and Prickett, C. S.: 1991, ‘Occurrence of DDT in human fat and milk’, Arch. Indust. Hyg. Occup. Med. 3, 245–246.
Mathur, V., Bhatnagar, P., Sharma, G., Achrya, V. and Saxena, R.: 2002, ‘Breast cancer incidence and exposure to pesticides among women originating from Jaipur’, Env. Int. 28, 331–336.
Mourkidou, E. P. and Milothridou, A.: 1990, ‘Residues of endosulfan in dry tobacco leaves and cigarettes’, Bull. Environ. Contam. Toxicol. 44, 394–400.
Raha, P., Agarwal, N. R. and Samante, S.: 1999, ‘Organochlorine pesticide residues in mother's milk’, in: N. P. Agnihotri, S. Walia and V. T. Gajbhiye (eds), Green Pesticides, Crop Protection and Safety Evaluation, Society of Pesticide Science, India, Indian Agricultural Research Institute, New Delhi, pp. 231–234.
Rathore, M., Bhatnagar, P., Mathur, D. and Saxena, G. N.: 2002, ‘Burden of organochlorine pesticides in blood and its effects on thyroid hormones in women’, Science Total Environ. 295, 207–215.
Rodriguez, R. L., Borja-Aburto, V. H., Santos- Burgoa, C., Waliszewskiy, S., Rios, C. and Cruz, V.: 1997, ‘Exposure assessment of workers applying DDT to control malaria in Veracruz, Mexico’, Environ. Health Perspect. 105(1), 98–101.
Sant Ana, L. S., Varsilieff, J. and Jokl, L.: 1989, ‘Levels of organochlorine insecticides in milk of mothers from urban and rural areas of Botucatu, sp. Brazil’, Bull. Environ. Contam. Toxicol. 42, 911–918.
Saxena, M. C., Siddiqui, M. K. J., Bhargava, A. K., Seth, T. D., Krishnamurti, C. R. and Kutty, D.: 1980, ‘Placental transfer of pesticides in humans’, Arch. Toxicol. 48, 38–47.
Saxena, M. C., Siddiqui, M. K. J., Seth, T. D., Krishnamurti, C. R., Bhargava, A. K. and Kutty, D.: 1981, ‘Organochlorine pesticides in specimens of women undergoing spontaneous abortions, premature or full term delivery’, J. Anal. Toxicol. 5, 22–24.
Schinas, V., Leotsinidas, M., Alexopoulos, A. and Kondakis, X. G.: 2000, ‘Organochlorine pesticide residues in human breast milk from southwest Greece: Associations with weekly food consumption patterns of mothers’, Arch. Environ. Health 55, 411–417.
Sharma, M.: 1995, Transplacental Movements of Pesticides in Women from Jaipur: Ph.D. Thesis, University of Rajasthan, Jaipur.
Sharma, M. and Bhatnaga, P.: 1996, ‘Organochlorine pesticides and preterm labour in human beings’, Current Sci.
Siddiqui, M. K. J. and Saxena, M. C.: 1985, ‘Placenta and milk as excretory route of lipophlic pesticides in women’, Human Toxicol. 4, 249–254.
Siddiqui, M. K. J., Saxena, M. C., Bhargava, A. K., Seth, T. D., Krishnamurti, C. R. and Kutty, D.: 1981, ‘Agrochemicals in maternal blood, milk and cord blood: A source of toxicant for prenates nad neonates’, Environ. Res. 24, 24–32.
Skarre, I. U., Tuveng, J. M. and Sande, H. A.: 1988, ‘Organochlorine pesticides and polychlorinated bipphenyls in maternal adipose tissue, blood and cord blood from mothers and their infants living in Norway’, Arch. Environ. Contam. Toxicol. 17, 555–563.
Spicer, P. E. and Kereu, R. K.: 1993, ‘Organochlorine insecticide residues in human breast milk: A survey of lactating mothers from remote area in Papua New Guinea’, Bull. Environ. Contam. Toxicol. 50, 540–546.
Takahashi, W., Saiden, D., Takei, G. and Wong, L.: 1981, ‘Organochlorine pesticide residues in human milk in Hawaii, 1979–1980’, Bull. Environ. Contam. Toxicol. 27, 506–511.
Talkie, G. H., Kouahikaua, S. N. and Leonh, G. H.: 1983, ‘Analysis of human milk samples collected in sass Hawaii for residues of organochlorine pesticides and polychlorobiphenyls’, Bull. Environ. Contam. Toxicol. 30, 606–613.
Travis, C. C., Hattmer-Frey, H. A. and Arms, A. D.: 1988, ‘Relationship between dietary intake of organochlorine chemicals and their concentrations in human adipose tissue and breast milk’, Arch. Environ. Contam. Toxicol. 17, 473–478.
Turrio-Baldassari, L., di Domenico, A., Iacovella, N., La Rocca, C., Mediati, M. G. and Rodriguez, F.: 1995, ‘PCB congener profile and contamination levels of Italian National and Regional diets’, Organohal. Comp. 26, 121–124.
Walker, J. B., Seddon, L., Mcmullen, E., Housmen, J., Tofflemire, K., Corriveau, Weber, J. P., Mills, C., Smith, S. and Oostadam: 2003, ‘Organochlorine levels in maternak and umbilical cord blood plasma in Arctic Canada’, Sci. Tot. Environ. 302, 27–52.
WHO/EURO: 1991, WHO Protocol for Second Round of Exposure Studies: Levels of PCBs and PCDFs in human milk.
Wong, C. K. C., Leung, K. M., Poon, B. H. T., Lan, C. Y. and Wong, M. H.: 2002, ‘Organochlorine hydrocarbons inhuman breast milk collected in Hong Kong and Guangzhou’, Arch. Environ. Contam. Toxicol. 43, 364–372.
Yang, J., Dongchun, S., Park, S., Chang, Y., Kim, D. and Ikonomou, M. G.: 2002, ‘PCDDs, PCDFs and PCBs concentrations in breast milk from two areas in Korea: Body burden of mothers and implication and implications for feeding infants’, Chemosphere 46, 419–428.
Yu, H., Zhu, Z., Zhao, X. and Wang, D.: 2003, ‘Levels of organochlorine pesticides in Beijing human milk, 1998’, Bull. Environ. Contam. Toxicol. 70, 193–197.
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Kumar, A., Baroth, A., Soni, I. et al. Organochlorine Pesticide Residues in Milk and Blood of Women from Anupgarh, Rajasthan, India. Environ Monit Assess 116, 1–7 (2006). https://doi.org/10.1007/s10661-006-7463-2
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DOI: https://doi.org/10.1007/s10661-006-7463-2