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Overcoming misled design and interpretation of randomised trials

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References

  1. Niedermaier T, Weigl K, Hoffmeister M, Brenner H. Diagnostic performance of flexible sigmoidoscopy combined with fecal immunochemical test in colorectal cancer screening: meta-analysis and modeling. Eur J Epidemiol. 2017;32(6):481–93.

    Article  PubMed  Google Scholar 

  2. Bretthauer M, Gondal G, Larsen K, Carlsen E, Eide TJ, Grotmol T, et al. Design, organization and management of a controlled population screening study for detection of colorectal neoplasia: attendance rates in the NORCCAP study (Norwegian Colorectal Cancer Prevention). Scand J Gastroenterol. 2002;37(5):568–73.

    Article  PubMed  CAS  Google Scholar 

  3. Hoff G, Grotmol T, Skovlund E, Bretthauer M. Norwegian Colorectal Cancer Prevention Study G. Risk of colorectal cancer seven years after flexible sigmoidoscopy screening: randomised controlled trial. Br Med J. 2009;338:b1846.

    Article  Google Scholar 

  4. Brenner H, Stock C, Hoffmeister M. Effect of screening sigmoidoscopy and screening colonoscopy on colorectal cancer incidence and mortality: systematic review and meta-analysis of randomised controlled trials and observational studies. Br Med J. 2014;348:g2467.

    Article  Google Scholar 

  5. Segnan N, Armaroli P, Bonelli L, Risio M, Sciallero S, Zappa M, et al. Once-only sigmoidoscopy in colorectal cancer screening: follow-up findings of the Italian randomized controlled trial–SCORE. J Natl Cancer Inst. 2011;103(17):1310–22.

    Article  PubMed  Google Scholar 

  6. Schoen RE, Pinsky PF, Weissfeld JL, Yokochi LA, Church T, Laiyemo AO, et al. Colorectal-cancer incidence and mortality with screening flexible sigmoidoscopy. N Engl J Med. 2012;366(25):2345–57.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  7. Atkin W, Wooldrage K, Parkin DM, Kralj-Hans I, MacRae E, Shah U, et al. Long term effects of once-only flexible sigmoidoscopy screening after 17 years of follow-up: the UK flexible sigmoidoscopy screening randomised controlled trial. Lancet. 2017;389(10076):1299–311.

    Article  PubMed  PubMed Central  Google Scholar 

  8. Bibbins-Domingo K, Grossman DC, Curry SJ, Davidson KW, Epling JW Jr, Garcia FA, et al. Screening for colorectal cancer: US preventive services task force recommendation statement. JAMA. 2016;315(23):2564–75.

    Article  PubMed  CAS  Google Scholar 

  9. Knudsen AB, Zauber AG, Rutter CM, Naber SK, Doria-Rose VP, Pabiniak C, et al. Estimation of benefits, burden, and harms of colorectal cancer screening strategies: modeling study for the US preventive services task force. J Am Med Assoc. 2016;315(23):2595–609.

    Article  CAS  Google Scholar 

  10. Fraser CG, Allison JE, Young GP, Halloran SP, Seaman H. A standard for faecal immunochemical tests for haemoglobin evaluation reporting (FITTER). Ann Clin Biochem. 2014;51(Pt 2):301–302. Available on: http://www.worldendo.org/wp-content/uploads/2016/08/weo_expert_working_group_fit_discussion_doc_no5_pu.pdf.

  11. Lee JK, Liles EG, Bent S, Levin TR, Corley DA. Accuracy of fecal immunochemical tests for colorectal cancer systematic review and meta-analysis. Ann Intern Med. 2014;160(3):171–81.

    Article  PubMed  PubMed Central  Google Scholar 

  12. Gies A, Bhardwaj M, Stock C, Schrotz-King P, Brenner H. Quantitative fecal immunochemical tests for colorectal cancer screening. Int J Cancer. 2018;143(2):234–44.

    Article  PubMed  CAS  Google Scholar 

  13. Brenner H, Stock C, Hoffmeister M. In the era of widespread endoscopy use, randomized trials may strongly underestimate the effects of colorectal cancer screening. J Clin Epidemiol. 2013;66(10):1144–50.

    Article  PubMed  Google Scholar 

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Niedermaier, T., Weigl, K. & Brenner, H. Overcoming misled design and interpretation of randomised trials. Eur J Epidemiol 33, 775–776 (2018). https://doi.org/10.1007/s10654-018-0419-3

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  • DOI: https://doi.org/10.1007/s10654-018-0419-3

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