Skip to main content

Advertisement

SpringerLink
Log in

Epidemiological and virological features of HBV infection in HIV-2 infected patients living in southeastern France

  • Brief Report
  • Published:
European Journal of Epidemiology Aims and scope Submit manuscript

Abstract

We studied HBV infection in 34 HIV-2–infected patients followed-up in Marseilles. Ten (29%) patients were chronically-infected with HBV, which represents a three-times higher rate than in HIV-1-infected patients in Europe. HBV occult infection was diagnosed in two patients. HBV genotype E was found in seven patients; its specificities and the reciprocal influence of HIV-2/HBV-co-infection remain to be evaluated.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Abbreviations

HBeAg:

HBe antigen

HBsAg:

HBs antigen

HBV:

hepatitis B virus

HIV-1:

human immunodeficiency virus type 1

HIV-2:

human immunodeficiency virus type 2

References

  1. Konopnicki D, Mocroft A, de Wit S, et al. 2005; Hepatitis B and HIV: Prevalence, AIDS progression, response to highly active antiretroviral therapy and increased mortality in the EuroSIDA cohort. AIDS 19(6):593–601

    Article  PubMed  Google Scholar 

  2. Ejele OA, Nwauche CA, Erhabor O, 2004; The prevalence of hepatitis B surface antigenaemia in HIV positive patients in the Niger Delta Nigeria. Niger J Med 13(2):175–179

    PubMed  CAS  Google Scholar 

  3. Mulders MN, Venard V, Njayou M, et al. Low genetic diversity despite hyperendemicity of hepatitis B virus genotype E throughout West Africa. J Infect Dis 2004; 190(2): 400–408. Epub 2004 Jun 22

    Google Scholar 

  4. Rouet F, Chaix ML, Inwoley A, et al. 2004; HBV and HCV prevalence and viraemia in HIV-positive and HIV-negative pregnant women in Abidjan, Cote d’Ivoire: The ANRS 1236 study. J Med Virol 74(1):34–40

    Article  PubMed  Google Scholar 

  5. Reeves JD, Doms RW, 2000; Human immunodeficiency virus type 2. J Gen Virol 83(Pt 6):1253–1265

    Google Scholar 

  6. Colson P, Henry M, Tivoli N, et al. 2005; Polymorphism and drug-selected mutations in the reverse transcriptase gene of HIV-2 from patients living in southeastern France. J Med Virol 75(3):381–390

    Article  PubMed  CAS  Google Scholar 

  7. Delfraissy JF, Epidémiologie. In: Flammarion M-S (ed), Prise en charge thérapeutique des personnes infectées par le VIH: Recommandations du groupe d’experts. 2004: 17–42

  8. Gerolami R, Henry M, Borentain P, Colson P, Botta D, Tamalet C. Fulminant hepatitis B associated with a specific insertion in the basal core promoter region of␣hepatitis B virus DNA after immunosuppressive treatment. Clin Infect Dis 2005; 40(4):e24–27. Epub 2005 Jan 21

    Google Scholar 

  9. Hunt CM, McGill JM, Allen MI, Condreay LD., 2000; Clinical relevance of hepatitis B viral mutations. Hepatology 31(5):1037–1044

    Article  PubMed  CAS  Google Scholar 

  10. Matheron S, Pueyo S, Damond F, et al. 2003; Factors associated with clinical progression in HIV-2 infected-patients: The French ANRS cohort. AIDS 17(18):2593–2601

    Article  PubMed  Google Scholar 

  11. Koyanagi T, Nakamuta M, Sakai H, et al. 2000; Analysis of HBs antigen negative variant of hepatitis B virus: Unique substitutions, Glu129 to Asp and Gly145 to Ala in the surface antigen gene. Med Sci Monit 6(6):1165–1169

    PubMed  CAS  Google Scholar 

  12. Protzer-Knolle U, Naumann U, Bartenschlager R, et al. 1998; Hepatitis B virus with antigenically altered hepatitis B surface antigen is selected by high-dose hepatitis B immune globulin after liver transplantation. Hepatology 27(1):254–263

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Laboratoire de Virologie, Fédération Hospitalière de Bactériologie-Virologie Clinique et d’Hygiène, CHRU Timone, 264 rue Saint-Pierre, 13385, Marseille cedex 05, France

    Philippe Colson, Mireille Henry, Anne Motte & Catherine Tamalet

  2. et CNRS UMR 6020 IFR48, Faculté de Médecine, Université de la Méditerranée, 27 boulevard Jean Moulin, 13385, Marseille cedex 05, France

    Philippe Colson, Mireille Henry, Anne Motte & Catherine Tamalet

  3. Service de Maladies Infectieuses, Hôpital Conception, boulevard Baille, 13005, Marseille, France

    Hervé Gallais

  4. Service de Maladies Infectieuses, Hôpital Nord, chemin des Bourrelys, 13915, Marseille cedex 05, France

    Jacques Moreau

  5. CISIH-SUD Département de Recherche Clinique, Hôpital Sainte Marguerite, boulevard Sainte-Marguerite, 13009, Marseille, France

    Isabelle Poizot-Martin

Authors
  1. Philippe Colson
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Mireille Henry
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Anne Motte
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Hervé Gallais
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Jacques Moreau
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Isabelle Poizot-Martin
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. Catherine Tamalet
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Philippe Colson.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Colson, P., Henry, M., Motte, A. et al. Epidemiological and virological features of HBV infection in HIV-2 infected patients living in southeastern France. Eur J Epidemiol 21, 615–618 (2006). https://doi.org/10.1007/s10654-006-9039-4

Download citation

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10654-006-9039-4

Keywords

Search

Navigation