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Developing Test Guidelines on invertebrate development and reproduction for the assessment of chemicals, including potential endocrine active substances—The OECD perspective

Ecotoxicology volume 16, pages 161–167 (2007)Cite this article

Abstract

The Organisation for Economic Co-operation and Development (OECD) Test Guidelines Programme is involved in the international harmonisation and validation of test methods to evaluate effects of chemicals, including potential endocrine active substances. To meet their existing and foreseen regulatory needs in this area, OECD member countries have encouraged the development of test methods and their emergence at the OECD level. Validation activities are underway in countries and industry to ascertain the relevance and reliability of these tests to enable future regulatory acceptance. This includes work on development and (sexual) reproduction of aquatic invertebrates. What is the importance of mechanistic information in regulating chemicals, and how to address the issue of possible endocrine disruption in invertebrates while integrating these tests in a regulatory scheme are the current questions faced by the OECD countries.

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Affiliations

  1. Organisation for Economic Co-operation and Development (OECD), 2 rue André-Pascal, F-75775, Paris Cedex 16, France

    Anne Gourmelon

  2. Chemicals Division, Finnish Environment Institute, P.O. Box 140, 00251, Helsinki, Finland

    Jukka Ahtiainen

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  1. Anne Gourmelon
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  2. Jukka Ahtiainen
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Correspondence to Anne Gourmelon.

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Opinions expressed in this paper do not necessarily represent those of the OECD and its member countries.

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Gourmelon, A., Ahtiainen, J. Developing Test Guidelines on invertebrate development and reproduction for the assessment of chemicals, including potential endocrine active substances—The OECD perspective . Ecotoxicology 16, 161–167 (2007). https://doi.org/10.1007/s10646-006-0105-1

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  • DOI: https://doi.org/10.1007/s10646-006-0105-1

Keywords

  • Invertebrates
  • Endocrine disrupters
  • Test methods