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Case of lens-induced uveitis associated with supernormal flicker ERG amplitudes after cataract surgery

  • Clinical Case Report
  • Published:
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Abstract

Purpose

To report our findings in a case of lens fragment-induced uveitis associated with supernormal flicker electroretinograms (ERGs) twenty months after the cataract surgery.

Methods

This is an observational case report. Full-field flicker ERGs were recorded with the RETeval system. Optical coherence tomography (OCT) and slit-lamp biomicroscopy were used to assess the uveitis during the follow-up period.

Results

A 70-year-old man, who had undergone cataract surgery 20 months earlier, visited our hospital with a complaint of decreased vision in his right eye. Slit-lamp biomicroscopy revealed corneal edema and a lens fragment was detected in the inferior part of the anterior chamber. OCT showed cystoid macular edema, and flicker ERGs showed a marked increase in the amplitude and a delay in the implicit time in the right eye. These abnormalities of the flicker ERGs improved gradually after the removal of lens fragment and application of topical anti-inflammatory medications.

Conclusion

Our case of lens-induced uveitis had supernormal flicker ERG amplitudes. Clinicians should be aware that eyes with uveitis can have larger-than-normal ERG amplitudes.

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Acknowledgements

We thank Professor Emeritus Duco I. Hamasaki of the Bascom Palmer Eye Institute of the University of Miami (Miami, FL, USA) for critical discussion and final manuscript revisions.

Funding

K. Kato, None; A. Sugawara, None; R. Nagashima, None; M Sugimoto, None; K Ikesugi, None; H Matsubara, Novartis (F); M. Takeuchi, None; M. Kondo, Novartis (F). Grant-in-Aid for Scientific Research C (MK, 18H02954 and 17K19721) from Ministry of Education, Culture, Sports, Science and Technology.

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Authors and Affiliations

  1. Department of Ophthalmology, Mie University Graduate School of Medicine, 2-174 Edobashi, Tsu, Mie, 514-8507, Japan

    Kumiko Kato, Asako Sugawara, Ryunosuke Nagashima, Masahiko Sugimoto, Kengo Ikesugi, Hisashi Matsubara, Maki Takeuchi & Mineo Kondo

Authors
  1. Kumiko Kato
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  2. Asako Sugawara
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  3. Ryunosuke Nagashima
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  4. Masahiko Sugimoto
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  5. Kengo Ikesugi
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  6. Hisashi Matsubara
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  7. Maki Takeuchi
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  8. Mineo Kondo
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Contributions

KK and MK wrote the main manuscript. AS, RN and MT collected the data. KK, MS, KI and HM analyzed the data. All authors reviewed the manuscript.

Corresponding author

Correspondence to Kumiko Kato.

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The authors declare that they have no conflict of interest.

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The patient has consented to the submission of the case report to the journal.

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All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

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No animals were used in this study.

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Kato, K., Sugawara, A., Nagashima, R. et al. Case of lens-induced uveitis associated with supernormal flicker ERG amplitudes after cataract surgery. Doc Ophthalmol 142, 233–238 (2021). https://doi.org/10.1007/s10633-020-09786-9

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  • DOI: https://doi.org/10.1007/s10633-020-09786-9

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