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Improved measurement of intersession latency in mfVEPs

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Abstract

Purpose

The purpose of the study is to present a method (Selfcorr) by which to measure intersession latency differences between multifocal VEP (mfVEP) signals.

Methods

The authors compared the intersession latency difference obtained using a correlation method (Selfcorr) against that obtained using a Template method. While the Template method cross-correlates the subject’s signals with a reference database, the Selfcorr method cross-correlates traces across subsequent recordings taken from the same subject.

Results

The variation in latency between intersession signals was 0.8 ± 13.6 and 0.5 ± 5.0 ms for the Template and Selfcorr methods, respectively, with a coefficient of variability C V_TEMPLATE = 15.83 and C V_SELFCORR = 5.68 (n = 18, p = 0.0002, Wilcoxon). The number of analyzable sectors with the Template and Selfcorr methods was 36.7 ± 8.5 and 45.3 ± 8.7, respectively (p = 0.0001, paired t test, two tailed).

Conclusions

The Selfcorr method produces smaller intersession mfVEP delays and variability over time than the Template method.

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References

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Acknowledgments

Research supported by Ministerio de Ciencia e Innovación (Spain) Grants TEC2011-26066, FIS PI11/00533 and RETICS RD12/0034/0006. We wish to thank Dr. D.C. Hood for his generosity with the software used to analyze the mfVEP data.

Conflict of interest

The authors claim no conflicts of interest.

Author information

Authors and Affiliations

  1. Biomedical Engineering Research Group, Department of Electronics, University of Alcalá, Madrid, Spain

    L. De Santiago, A. Fernández, J. M. Rodríguez-Ascariz, R. Barea, J. M. Miguel-Jiménez, C. Amo & L. Boquete

  2. Department of Surgery and Medical Sciences, University of Alcalá, Madrid, Spain

    R. Blanco & C. Pérez-Rico

  3. Department of Psychiatry, University Hospital of Guadalajara, Guadalajara, Spain

    E. M. Sánchez-Morla

Authors
  1. L. De Santiago
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  2. A. Fernández
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  3. R. Blanco
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  4. C. Pérez-Rico
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  5. J. M. Rodríguez-Ascariz
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  6. R. Barea
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  7. J. M. Miguel-Jiménez
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  8. C. Amo
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  9. E. M. Sánchez-Morla
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  10. L. Boquete
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Corresponding author

Correspondence to L. Boquete.

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De Santiago, L., Fernández, A., Blanco, R. et al. Improved measurement of intersession latency in mfVEPs. Doc Ophthalmol 129, 65–69 (2014). https://doi.org/10.1007/s10633-014-9438-x

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  • DOI: https://doi.org/10.1007/s10633-014-9438-x

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