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A Response-able Diagnosis: Type 2 Autoimmune Pancreatitis in the Setting of Ulcerative Colitis

  • Multicenter Seminars: IBD (MUSE: IBD)
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Reprinted from: Jun SY, Chun J, Kim SJ, Oh D, Kim JH, Kim MH, Hong SM. Granulocytic epithelial lesion (GEL) in heterotopic pancreas. Pancreatology. 2022 Apr;22(3):435–442, with permission from Elsevier

Fig. 1

Adapted from Zen Y. Type 2 Autoimmune Pancreatitis: Consensus and Controversies. Gut Liver. 2022 16(3):357–365. With permission by https://www.gutnliver.org under Creative Commons attribution. https://creativecommons.org/licenses/by-nc/4.0

Data availability

No datasets were generated or analysed during the current study.

Abbreviations

AIP:

Autoimmune pancreatitis

GEL:

Granulocyte epithelial lesion

IBD:

Inflammatory bowel disease

NOS:

Not otherwise specified

References

  1. Ball WP, Baggenstoss AH, Bargen JA. Pancreatic lesions associated with chronic ulcerative colitis. Arch Pathol (Chic). 1950;50:347–358.

    CAS  PubMed  Google Scholar 

  2. Sarles H, Sarles JC, Muratore R, Guien C. Chronic inflammatory sclerosis of the pancreas—an autonomous pancreatic disease? Am J Dig Dis. 1961;6:688–698. https://doi.org/10.1007/BF02232341.

    Article  CAS  PubMed  Google Scholar 

  3. Massironi S, Fanetti I, Vigano C et al. Systematic review-pancreatic involvement in inflammatory bowel disease. Aliment Pharmacol Ther. 2022;55:1478–1491. https://doi.org/10.1111/apt.16949.

    Article  PubMed  PubMed Central  Google Scholar 

  4. Fousekis FS, Theopistos VI, Katsanos KH, Christodoulou DK. Pancreatic involvement in inflammatory bowel disease: a review. J Clin Med Res. 2018;10:743–751. https://doi.org/10.14740/jocmr3561w.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  5. Smyk DS, Rigopoulou EI, Koutsoumpas AL, Kriese S, Burroughs AK, Bogdanos DP. Autoantibodies in autoimmune pancreatitis. Int J Rheumatol. 2012;2012:940831. https://doi.org/10.1155/2012/940831.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  6. Kadayakkara DK, Beatty PL, Turner MS, Janjic JM, Ahrens ET, Finn OJ. Inflammation driven by overexpression of the hypoglycosylated abnormal mucin 1 (MUC1) links inflammatory bowel disease and pancreatitis. Pancreas. 2010;39:510–515. https://doi.org/10.1097/MPA.0b013e3181bd6501.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  7. Conti Bellocchi MC, Marconato E, Lamonaca L et al. The features and clinical outcomes of inflammatory bowel disease associated with autoimmune pancreatitis: A greater awareness is needed. Medicine (Baltimore). 2022;101:e28602. https://doi.org/10.1097/MD.0000000000028602.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  8. Ueki T, Kawamoto K, Otsuka Y et al. Prevalence and clinicopathological features of autoimmune pancreatitis in Japanese patients with inflammatory bowel disease. Pancreas. 2015;44:434–440. https://doi.org/10.1097/MPA.0000000000000261.

    Article  CAS  PubMed  Google Scholar 

  9. Ramos LR, Sachar DB, DiMaio CJ, Colombel JF, Torres J. Inflammatory bowel disease and pancreatitis: a review. J Crohns Colitis. 2016;10:95–104. https://doi.org/10.1093/ecco-jcc/jjv153.

    Article  PubMed  Google Scholar 

  10. Shimosegawa T, Chari ST, Frulloni L et al. International consensus diagnostic criteria for autoimmune pancreatitis: guidelines of the International Association of Pancreatology. Pancreas. 2011;40:352–358. https://doi.org/10.1097/MPA.0b013e3182142fd2.

    Article  PubMed  Google Scholar 

  11. Fukuda S, Akiyama S, Tarakji A, Hamdeh S, Suzuki H, Tsuchiya K. Prevalence and clinical features of patients with autoimmune pancreatitis and inflammatory bowel disease: a systematic review and meta-analysis. J Gastroenterol Hepatol. 2022;37:1474–1484. https://doi.org/10.1111/jgh.15894.

    Article  CAS  PubMed  Google Scholar 

  12. de Pretis N, Frulloni L. Autoimmune pancreatitis type 2. Curr Opin Gastroenterol. 2020;36:417–420. https://doi.org/10.1097/MOG.0000000000000655.

    Article  CAS  PubMed  Google Scholar 

  13. Bezzio C, Della Corte C, Vernero M, Di Luna I, Manes G, Saibeni S. Inflammatory bowel disease and immune-mediated inflammatory diseases: looking at the less frequent associations. Therap Adv Gastroenterol. 2022;15:17562848221115312. https://doi.org/10.1177/17562848221115312.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  14. Majumder S, Takahashi N, Chari ST. Autoimmune pancreatitis. Dig Dis Sci. 2017;62:1762–1769. https://doi.org/10.1007/s10620-017-4541-y.

    Article  CAS  PubMed  Google Scholar 

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Authors and Affiliations

  1. Department of Gastroenterology and Hepatology, Kaiser Permanente San Francisco Medical Center, 2350 Geary Boulevard, 2nd Floor, San Francisco, CA, 94115, USA

    Kevin Kane, Fernando S. Velayos, Jeffrey K. Lee & Kunal Karia

  2. Department of Pathology, Kaiser Permanente San Francisco Medical Center, San Francisco, CA, USA

    Sarah Cherny

Authors
  1. Kevin Kane
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  2. Fernando S. Velayos
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  3. Jeffrey K. Lee
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  4. Sarah Cherny
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Contributions

KK and FV wrote the main manuscript text. All authors reviewed the manuscript.

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Correspondence to Kevin Kane.

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The authors declare no competing interests.

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Kane, K., Velayos, F.S., Lee, J.K. et al. A Response-able Diagnosis: Type 2 Autoimmune Pancreatitis in the Setting of Ulcerative Colitis. Dig Dis Sci (2024). https://doi.org/10.1007/s10620-024-08408-7

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