Skip to main content
SpringerLink
Log in

Probability Regarding the Tumor-Promoter Role of Porphyromonas gingivalis for the Gastric Carcinogenesis

  • Correspondence
  • Published:
Digestive Diseases and Sciences Aims and scope Submit manuscript

A Correspondence to this article was published on 18 May 2024

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Data availability

No datasets were generated or analyzed during the current study.

References

  1. Oriuchi M, Lee S, Uno K et al. Porphyromonas gingivalis lipopolysaccharide damages mucosal barrier to promote gastritis-associated carcinogenesis. Dig Dis Sci 2024;69:95–111. https://doi.org/10.1007/s10620-023-08142-6

    Article  CAS  PubMed  Google Scholar 

  2. Li CX, Liu H, Gong ZC. What is the potential interplay between microbiome and tumor microenvironment in oral squamous cell carcinomas? Asian Pac J Cancer Prev 2022;23:2199–2213.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  3. Li CX, Su Y, Gong ZC et al. Porphyromonas gingivalis activation of tumor-associated macrophages via DOK3 promotes recurrence of oral squamous cell carcinoma. Med Sci Monit 2022;28:e937126.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  4. Lamont RJ, Fitzsimonds ZR, Wang H et al. Role of Porphyromonas gingivalis in oral and orodigestive squamous cell carcinoma. Periodontol 2000 2022;89:154–165.

    Article  PubMed  PubMed Central  Google Scholar 

  5. Li CX, Li MQ, Wei W et al. Evidence-based evaluation regarding the impact of Porphyromonas gingivalis on the malignancies of digestive system and its possible pathogenic mechanism. J Dig Oncol 2023;15:268–282 (Chinese).

    Google Scholar 

  6. Yuan X, Liu Y, Kong J et al. Different frequencies of Porphyromonas gingivalis infection in cancers of the upper digestive tract. Cancer Lett 2017;404:1–7.

    Article  CAS  PubMed  Google Scholar 

  7. Li CX, Li MQ, Wei W et al. Association of DOK3 and infiltrated tumor-associated macrophages with risk for the prognosis of Porphyromonas gingivalis-infected oral cancer: a 12-year data analysis based on a tertiary teaching hospital. BMC Cancer 2024;24:534.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  8. Kiseleva V, Vishnyakova P, Elchaninov A et al. Biochemical and molecular inducers and modulators of M2 macrophage polarization in clinical perspective. Int Immunopharmacol 2023;122:110583.

    Article  PubMed  Google Scholar 

  9. Li CX, Gong ZC, Zheng NB. Progress in the regulatory effects of tumor-derived exosomes on macrophage polarization. Chin J Microbiol Immunol 2023;43:76–83 (Chinese).

    CAS  Google Scholar 

  10. Christofides A, Strauss L, Yeo A et al. The complex role of tumor-infiltrating macrophages. Nat Immunol 2022;23:1148–1156.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

Download references

Acknowledgments

We would like to express our cordial appreciation to the support of Dr. Ningbo Zheng (Comprehensive Cancer Center, Wake Forest Baptist Health; Department of Microbiology & Immunology, Wake Forest School of Medicine. Winston-Salem, NC 27101, USA), as well as Prof. Hui Liu (Department of Oral and Maxillofacial Surgery, Shanghai Stomatological Hospital & School of Stomatology, Shanghai Key Laboratory of Craniomaxillofacial Development and Diseases, Fudan University. Shanghai 200003, P. R. China) for the professional assistance to our work.

Funding

This work was funded by National Natural Science Foundation of China (No. 82360481); Open Project of Hubei Province Key Laboratory of Oral and Maxillofacial Development and Regeneration (No. 2022kqhm008); Xinjiang Postgraduate Scientific Research Innovation Project (No. XJ2023G174).

Author information

Authors and Affiliations

  1. Department of Oral and Maxillofacial Oncology & Surgery, The First Affiliated Hospital of Xinjiang Medical University, School/Hospital of Stomatology, Stomatological Research Institute of Xinjiang Uygur Autonomous Region, No. 137 Liyushan South Road, Urumqi, 830054, People’s Republic of China

    Chen-xi Li & Zhong-cheng Gong

  2. Hubei Province Key Laboratory of Oral and Maxillofacial Development and Regeneration, School of Stomatology, Tongji Medical College, Union Hospital, Huazhong University of Science and Technology, Wuhan, 430022, People’s Republic of China

    Chen-xi Li

  3. Department of Pathology, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, 830054, People’s Republic of China

    Jing-wen Yu

Authors
  1. Chen-xi Li
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Jing-wen Yu
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Zhong-cheng Gong
    View author publications

    You can also search for this author in PubMed Google Scholar

Contributions

C. Li wrote the original draft and revised the manuscript. J. Yu and Z. Gong reviewed the manuscript.

Corresponding author

Correspondence to Zhong-cheng Gong.

Ethics declarations

Conflict of interest

No potential conflict of interest was reported by the author(s).

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Li, Cx., Yu, Jw. & Gong, Zc. Probability Regarding the Tumor-Promoter Role of Porphyromonas gingivalis for the Gastric Carcinogenesis. Dig Dis Sci 69, 2260–2261 (2024). https://doi.org/10.1007/s10620-024-08357-1

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10620-024-08357-1

Search

Navigation