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Drains, Germs, or Steel: Multidisciplinary Management of Acute Colonic Diverticulitis

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Abstract

The medical and surgical management of uncomplicated diverticulitis has changed over the last several years. Although immunocompetent patients or those without comorbidities can be treated with antibiotics as an outpatient, the efficacy of high-fiber intake or drugs such as mesalamine or rifaximin is not yet clearly established in the treatment of acute episodes and in the prevention of recurrences. On the other hand, the choice between antibiotic treatment and percutaneous drainage is not always obvious in diverticulitis complicated by abscess formation, especially for larger abscesses; although the results of studies comparing the two approaches remain controversial, surgery must be pursued for abscesses > 8 cm. For emergency surgery, the debate is still ongoing regarding laparoscopic lavage and surgical resection followed by primary anastomosis, since for both approaches the published reports are not in agreement regarding possible benefits. Therefore, these approaches are recommended only for selected patients under the care of experienced surgeons. Also, the contribution of elective surgery toward the overall approach has been revised; currently, it is reserved primarily for patients with a high risk of recurrence and whenever more conservative treatments were not effective.

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Abbreviations

5-ASA:

5-Aminosalicylic acid

AD:

Acute diverticulitis

CRP:

C reactive protein

CT:

Computed tomography

DD:

Diverticular disease

HP:

Hartmann’s procedure

IBS:

Inflammatory bowel disease

LL:

Laparoscopic lavage

NSAIDs:

Non-steroidal anti-inflammatory drugs

PCD:

Percutaneous drainage

RCTs:

Randomized control trials

SUDD:

Symptomatic uncomplicated diverticular disease

WSES:

World Society of Emergency Surgery

References

  1. Violi A, Cambiè G, Miraglia C, et al. Epidemiology and risk factors for diverticular disease. Acta Biomed. 2018;89:107–112.

    PubMed  Google Scholar 

  2. Sharara AI, Ziade N, Shayto RH, et al. The natural history of incidental colonic diverticulosis on screening colonoscopy. Can J Gastroenterol Hepatol. 2018;2018:3690202.

    PubMed  PubMed Central  Google Scholar 

  3. Strate LL, Morris AM. Epidemiology, pathophysiology, and treatment of diverticulitis. Gastroenterology. 2019;156:1282–1298.

    PubMed  PubMed Central  Google Scholar 

  4. Sartelli M, Weber DG, Kluger Y, et al. 2020 update of the WSES guidelines for the management of acute colonic diverticulitis in the emergency setting. World J Emerg Surg. 2020;15:32.

    PubMed  PubMed Central  Google Scholar 

  5. Zullo A. Medical hypothesis: speculating on the pathogenesis of acute diverticulitis. Ann Gastroenterol. 2018;31:747–749.

    PubMed  PubMed Central  Google Scholar 

  6. Carabotti M, Annibale B, Severi C, et al. Role of fiber in symptomatic uncomplicated diverticular disease: a systematic review. Nutrients. 2017;9:161.

    PubMed Central  Google Scholar 

  7. Nagata N, Sakamoto K, Arai T, et al. Visceral abdominal obesity measured by computed tomography is associated with increased risk of colonic diverticulosis. J Clin Gastroenterol. 2015;49:816–822.

    PubMed  Google Scholar 

  8. Wijarnpreecha K, Ahuja W, Chesdachai S, et al. Obesity and the risk of colonic diverticulosis: a meta-analysis. Dis Colon Rectum. 2018;61:476–483.

    PubMed  Google Scholar 

  9. Tursi A, Mastromarino P, Capobianco D, et al. Assessment of fecal microbiota and fecal metabolome in symptomatic uncomplicated diverticular disease of the colon. J Clin Gastroenterol. 2016;50:S9–S12.

    CAS  PubMed  Google Scholar 

  10. Barbara G, Scaioli E, Barbaro MR, et al. Gut microbiota, metabolome and immune signatures in patients with uncomplicated diverticular disease. Gut. 2017;66:1252–1261.

    CAS  PubMed  Google Scholar 

  11. Tursi A. Current and evolving concepts on the pathogenesis of diverticular disease. J Gastrointest Liver Dis. 2019;28:225–235.

    Google Scholar 

  12. Mortensen LQ, Burcharth J, Andresen K, et al. An 18-year nationwide cohort study on the association between diverticulitis and colon cancer. Ann Surg. 2017;265:954–959.

    PubMed  Google Scholar 

  13. Soh NYT, Chia DKA, Teo NZ, et al. Prevalence of colorectal cancer in acute uncomplicated diverticulitis and the role of the interval colonoscopy. Int J Colorectal Dis. 2018;33:991–994.

    PubMed  Google Scholar 

  14. Meyer J, Orci LA, Combescure C, et al. Risk of colorectal cancer in patients with acute diverticulitis: a systematic review and meta-analysis of observational studies. Clin Gastroenterol Hepatol. 2019;17:1448–1456.

    PubMed  Google Scholar 

  15. Rottier SJ, van Dijk ST, van Geloven AAW, et al. Meta-analysis of the role of colonoscopy after an episode of left-sided acute diverticulitis. Br J Surg. 2019;106:988–997.

    CAS  PubMed  PubMed Central  Google Scholar 

  16. Hinchey EJ, Schaal PH, Richards MB. Treatment of perforated diverticular disease of the colon. Adv Surg. 1978;12:85–109.

    CAS  PubMed  Google Scholar 

  17. Stollman N, Smalley W, Hirano I, AGA Institute Clinical Guidelines Committee. American Gastroenterological Association Institute guideline on the management of acute diverticulitis. Gastroenterology. 2015;149:1944–1949.

    PubMed  Google Scholar 

  18. Francis NK, Sylla P, Abou-Khalil M, et al. EAES and SAGES 2018 consensus conference on acute diverticulitis management: evidence-based recommendations for clinical practice. Surg Endosc. 2019;33:2726–2741.

    PubMed  PubMed Central  Google Scholar 

  19. Ceresoli M, Lo Bianco G, Gianotti L, et al. Inflammation management in acute diverticulitis: current perspectives. J Inflamm Res. 2018;11:239–246.

    CAS  PubMed  PubMed Central  Google Scholar 

  20. Lanas A, Abad-Baroja D, Lanas-Gimeno A. Progress and challenges in the management of diverticular disease: which treatment? Therap Adv Gastroenterol. 2018;11:1756284818789055.

    PubMed  PubMed Central  Google Scholar 

  21. Daniels L, Ünlü Ç, de Korte N, et al. Randomized clinical trial of observational versus antibiotic treatment for a first episode of CT-proven uncomplicated acute diverticulitis. Br J Surg. 2017;104:52–61.

    CAS  PubMed  Google Scholar 

  22. Buchwald P, Dixon L, Wakeman CJ, et al. Hinchey I and II diverticular abscesses: long-term outcome of conservative treatment. ANZ J Surg. 2017;87:1011–1014.

    PubMed  Google Scholar 

  23. Emile SH, Elfeki H, Sakr A, et al. Management of acute uncomplicated diverticulitis without antibiotics: a systematic review, meta-analysis, and meta-regression of predictors of treatment failure. Tech Coloproctol. 2018;22:499–509.

    CAS  PubMed  Google Scholar 

  24. Mayl J, Marchenko M, Frierson E. Management of acute uncomplicated diverticulitis may exclude antibiotic therapy. Cureus. 2017;9:e1250.

    PubMed  PubMed Central  Google Scholar 

  25. Azhar N, Kulstad H, Pålsson B, et al. Acute uncomplicated diverticulitis managed without antibiotics—difficult to introduce a new treatment protocol but few complications. Scand J Gastroenterol. 2019;54:64–68.

    CAS  PubMed  Google Scholar 

  26. Mocanu V, Dang JT, Switzer N, et al. The role of antibiotics in acute uncomplicated diverticulitis: a systematic review and meta-analysis. Am J Surg. 2018;216:604–609.

    PubMed  Google Scholar 

  27. Au S, Aly EH. Treatment of uncomplicated acute diverticulitis without antibiotics: a systematic review and meta-analysis. Dis Colon Rectum. 2019;62:1533–1547.

    PubMed  Google Scholar 

  28. Bolkenstein HE, Draaisma WA, van de Wall B, et al. Treatment of acute uncomplicated diverticulitis without antibiotics: risk factors for treatment failure. Int J Colorectal Dis. 2018;33:863–869.

    CAS  PubMed  PubMed Central  Google Scholar 

  29. Swanson SM, Strate LL. Acute colonic diverticulitis. Ann Intern Med. 2018;168:65–80.

    Google Scholar 

  30. Jaung R, Robertson J, Vather R, et al. Changes in the approach to acute diverticulitis. ANZ J Surg. 2015;85:715–719.

    PubMed  Google Scholar 

  31. Tursi A, Papa A, Danese S. Review article: the pathophysiology and medical management of diverticulosis and diverticular disease of the colon. Aliment Pharmacol Ther. 2015;42:664–684.

    CAS  PubMed  Google Scholar 

  32. Bolkenstein HE, van Dijk ST, Consten ECJ, et al. Conservative treatment in diverticulitis patients with pericolic extraluminal air and the role of antibiotic treatment. J Gastrointest Surg. 2019;23:2269–2276.

    CAS  PubMed  PubMed Central  Google Scholar 

  33. van Dijk ST, Daniels L, Nio CY, et al. Predictive factors on CT imaging for progression of uncomplicated into complicated acute diverticulitis. Int J Colorectal Dis. 2017;32:1693–1698.

    PubMed  PubMed Central  Google Scholar 

  34. van Dijk ST, Bos K, de Boer MGJ, et al. A systematic review and meta-analysis of outpatient treatment for acute diverticulitis. Int J Colorectal Dis. 2018;33:505–512.

    PubMed  PubMed Central  Google Scholar 

  35. Cirocchi R, Randolph JJ, Binda GA, et al. Is the outpatient management of acute diverticulitis safe and effective? A systematic review and meta-analysis. Tech Coloproctol. 2019;23:87–100.

    CAS  PubMed  Google Scholar 

  36. Balasubramanian I, Fleming C, Mohan HM, et al. Out-patient management of mild or uncomplicated diverticulitis: a systematic review. Dig Surg. 2017;34:151–160.

    PubMed  Google Scholar 

  37. Isacson D, Andreasson K, Nikberg M, et al. Outpatient management of acute uncomplicated diverticulitis results in health-care cost savings. Scand J Gastroenterol. 2018;53:449–452.

    PubMed  Google Scholar 

  38. Rezapour M, Ali S, Stollman N. Diverticular disease: an update on pathogenesis and management. Gut Liver. 2018;12:125–132.

    CAS  PubMed  Google Scholar 

  39. Banasiewicz T, Francuzik W, Bobkiewicz A, et al. The influence of rifaximin on diverticulitis rate and quality of life in patients with diverticulosis. Pol Przegl Chir. 2017;89:22–31.

    PubMed  Google Scholar 

  40. Festa V, Spila Alegiani S, Chiesara F, et al. Retrospective comparison of long-term ten-day/month rifaximin or mesalamine in prevention of relapse in acute diverticulitis. Eur Rev Med Pharmacol Sci. 2017;21:1397–1404.

    CAS  PubMed  Google Scholar 

  41. van Dijk ST, Rottier SJ, van Geloven AAW, et al. Conservative treatment of acute colonic diverticulitis. Curr Infect Dis Rep. 2017;19:44.

    PubMed  PubMed Central  Google Scholar 

  42. Cremon C, Carabotti M, Cuomo R, et al. Italian nationwide survey of pharmacologic treatments in diverticular disease: results from the REMAD registry. United Eur Gastroenterol J. 2019;7:815–824.

    Google Scholar 

  43. Iannone A, Ruospo M, Wong G, et al. Mesalamine for people with diverticular disease: a systematic review of randomized controlled trials. Can J Gastroenterol Hepatol. 2018;2018:5437135.

    PubMed  PubMed Central  Google Scholar 

  44. Picchio M, Elisei W, Tursi A. Mesalamine to treat symptomatic uncomplicated diverticular disease and to prevent acute diverticulitis occurrence. A systematic review with meta-analysis of randomized, placebo-controlled trials. J Gastrointest Liver Dis. 2018;27:291–297.

    Google Scholar 

  45. Khan RMA, Ali B, Hajibandeh S, et al. Effect of mesalamine on recurrence of diverticulitis in patients with symptomatic uncomplicated diverticular disease: a meta-analysis with trial sequential analysis of randomized controlled trials. Colorectal Dis. 2018;20:469–478.

    CAS  PubMed  Google Scholar 

  46. Khan MA, Ali B, Lee WM, et al. Mesalamine does not help prevent recurrent acute colonic diverticulitis: meta-analysis of randomized, placebo-controlled trials. Am J Gastroenterol. 2016;111:579–581.

    PubMed  Google Scholar 

  47. Elisei W, Tursi A. Recent advances in the treatment of colonic diverticular disease and prevention of acute diverticulitis. Ann Gastroenterol. 2016;29:24–32.

    PubMed  PubMed Central  Google Scholar 

  48. Lahner E, Bellisario C, Hassan C, et al. Probiotics in the treatment of diverticular disease. A systematic review. J Gastrointest Liver Dis. 2016;25:79–86.

    Google Scholar 

  49. Lambrichts DPV, Bolkenstein HE, van der Does DCHE, et al. Multicentre study of non-surgical management of diverticulitis with abscess formation. Br J Surg. 2019;106:458–466.

    CAS  PubMed  PubMed Central  Google Scholar 

  50. Lambrichts DPV, Birindelli A, Tonini V, et al. The multidisciplinary management of acute complicated diverticulitis. Inflamm Intest Dis. 2018;3:80–90.

    PubMed  PubMed Central  Google Scholar 

  51. Mali J, Mentula P, Leppäniemi A, et al. Determinants of treatment and outcomes of diverticular abscesses. World J Emerg Surg. 2019;14:31.

    PubMed  PubMed Central  Google Scholar 

  52. Gregersen R, Mortensen LQ, Burcharth J, et al. Treatment of patients with acute colonic diverticulitis complicated by abscess formation: a systematic review. Int J Surg. 2016;35:201–208.

    PubMed  Google Scholar 

  53. Strauss Und von Torney M, Moffa G, Kaech M, et al. Risk of emergency surgery or death after initial nonoperative management of complicated diverticulitis in Scotland and Switzerland. JAMA Surg. 2020;155:1–7.

    Google Scholar 

  54. Theodoropoulos D. Current options for the emergency management of diverticular disease and options to reduce the need for colostomy. Clin Colon Rectal Surg. 2018;31:229–235.

    PubMed  PubMed Central  Google Scholar 

  55. O’Sullivan GC, Murphy D, O’Brien MG, et al. Laparoscopic management of generalized peritonitis due to perforated colonic diverticula. Am J Surg. 1996;171:432–434.

    PubMed  Google Scholar 

  56. Gehrman J, Angenete E, Björholt I, et al. Health economic analysis of laparoscopic lavage versus Hartmann’s procedure for diverticulitis in the randomized DILALA trial. Br J Surg. 2016;103:1539–1547.

    CAS  PubMed  PubMed Central  Google Scholar 

  57. Vennix S, van Dieren S, Opmeer BC, et al. Cost analysis of laparoscopic lavage compared with sigmoid resection for perforated diverticulitis in the Ladies trial. Br J Surg. 2017;104:62–68.

    CAS  PubMed  Google Scholar 

  58. Ceresoli M, Coccolini F, Montori G, et al. Laparoscopic lavage versus resection in perforated diverticulitis with purulent peritonitis: a meta-analysis of randomized controlled trials. World J Emerg Surg. 2016;11:42.

    PubMed  PubMed Central  Google Scholar 

  59. Swank HA, Vermeulen J, Lange JF, et al. The ladies trial: laparoscopic peritoneal lavage or resection for purulent peritonitis and Hartmann’s procedure or resection with primary anastomosis for purulent or faecal peritonitis in perforated diverticulitis (NTR2037). BMC Surg. 2010;10:29.

    PubMed  PubMed Central  Google Scholar 

  60. Thornell A, Angenete E, Gonzales E, et al. Treatment of acute diverticulitis laparoscopic lavage vs. resection (DILALA): study protocol for a randomised controlled trial. Trials. 2011;12:186.

    PubMed  PubMed Central  Google Scholar 

  61. Schultz JK, Yaqub S, Wallon C, et al. Laparoscopic lavage vs primary resection for acute perforated diverticulitis: the SCANDIV randomized clinical trial. JAMA. 2015;314:1364–1375.

    CAS  PubMed  Google Scholar 

  62. Vennix S, Musters GD, Mulder IM, et al. Laparoscopic peritoneal lavage or sigmoidectomy for perforated diverticulitis with purulent peritonitis: a multicentre, parallel-group, randomised, open-label trial. Lancet. 2015;386:1269–1277.

    PubMed  Google Scholar 

  63. Angenete E, Thornell A, Burcharth J, et al. Laparoscopic lavage is feasible and safe for the treatment of perforated diverticulitis with purulent peritonitis: the first results from the randomized controlled trial DILALA. Ann Surg. 2016;263:117–122.

    PubMed  Google Scholar 

  64. Cirocchi R, Di Saverio S, Weber DG, et al. Laparoscopic lavage versus surgical resection for acute diverticulitis with generalised peritonitis: a systematic review and meta-analysis. Tech Coloproctol. 2017;21:93–110.

    CAS  PubMed  Google Scholar 

  65. Shaikh FM, Stewart PM, Walsh SR, et al. Laparoscopic peritoneal lavage or surgical resection for acute perforated sigmoid diverticulitis: a systematic review and meta-analysis. Int J Surg. 2017;38:130–137.

    PubMed  Google Scholar 

  66. Cirocchi R, Trastulli S, Vettoretto N, et al. Laparoscopic peritoneal lavage: a definitive treatment for diverticular peritonitis or a “bridge” to elective laparoscopic sigmoidectomy? A systematic review. Medicine (Baltimore). 2015;94:e334.

    Google Scholar 

  67. Binda GA, Bonino MA, Siri G, et al. Multicentre international trial of laparoscopic lavage for Hinchey III acute diverticulitis (LLO Study). Br J Surg. 2018;105:1835–1843.

    CAS  PubMed  Google Scholar 

  68. Di Saverio S, Birindelli A, Catena F, et al. The Ladies Trial: premature termination of the LOLA arm and increased adverse events incidence after laparoscopic lavage may be influenced by inter-hospital and inter-operator variability? Take-home messages from a center with laparoscopic colorectal expertise. Int J Surg. 2016;36:118–120.

    PubMed  Google Scholar 

  69. Cirocchi R, Afshar S, Di Saverio S, et al. A historical review of surgery for peritonitis secondary to acute colonic diverticulitis: from Lockhart-Mummery to evidence-based medicine. World J Emerg Surg. 2017;12:14.

    PubMed  PubMed Central  Google Scholar 

  70. Ogino T, Mizushima T, Matsuda C, et al. Essential updates 2018/2019: colorectal (benign): recent updates (2018–2019) in the surgical treatment of benign colorectal diseases. Ann Gastroenterol Surg. 2019;4:30–38.

    PubMed  PubMed Central  Google Scholar 

  71. Abraha I, Binda GA, Montedori A, et al. Laparoscopic versus open resection for sigmoid diverticulitis. Cochrane Database Syst Rev. 2017;11:CD009277.

    PubMed  Google Scholar 

  72. Moghadamyeghaneh Z, Carmichael JC, Smith BR, et al. A comparison of outcomes of emergent, urgent, and elective surgical treatment of diverticulitis. Am J Surg. 2015;210:838–845.

    PubMed  Google Scholar 

  73. Köckerling F. Emergency surgery for acute complicated diverticulitis. Viszeralmedizin. 2015;31:107–110.

    PubMed  PubMed Central  Google Scholar 

  74. Schuster KM, Holena DN, Salim A, et al. American Association for the Surgery of Trauma emergency general surgery guideline summaries 2018: acute appendicitis, acute cholecystitis, acute diverticulitis, acute pancreatitis, and small bowel obstruction. Trauma Surg Acute Care Open. 2019;4:e000281.

    PubMed  PubMed Central  Google Scholar 

  75. Sherman KL, Wexner SD. Considerations in stoma reversal. Clin Colon Rectal Surg. 2017;30:172–177.

    PubMed  PubMed Central  Google Scholar 

  76. Binda GA, Papa A, Persiani R, et al. Hot topics in surgical management of acute diverticulitis. J Gastrointest Liver Dis. 2019;28:29–34.

    Google Scholar 

  77. Simianu VV, Flum DR. Rethinking elective colectomy for diverticulitis: a strategic approach to population health. World J Gastroenterol. 2014;20:16609–16614.

    PubMed  PubMed Central  Google Scholar 

  78. Al Harakeh H, Paily AJ, Doughan S, et al. Recurrent acute diverticulitis: when to operate? Inflamm Intest Dis. 2018;3:91–99.

    PubMed  PubMed Central  Google Scholar 

  79. Pesce A, Barchitta M, Agodi A, et al. Comparison of clinical and pathological findings of patients undergoing elective colectomy for uncomplicated diverticulitis. Sci Rep. 2020;10:8854.

    CAS  PubMed  PubMed Central  Google Scholar 

  80. Khan RMA, Hajibandeh S, Hajibandeh S. Early elective versus delayed elective surgery in acute recurrent diverticulitis: a systematic review and meta-analysis. Int J Surg. 2017;46:92–101.

    PubMed  Google Scholar 

  81. Roscio F, Grillone G, Frattini P, et al. Effectiveness of elective laparoscopic treatment for colonic diverticulitis. JSLS. 2015;19(e2014):00120.

    Google Scholar 

  82. Justin V, Uranues S, Rabl H, et al. Quality of life in uncomplicated recurrent diverticulitis: surgical vs. conservative treatment. Sci Rep. 2020;10:10261.

    CAS  PubMed  PubMed Central  Google Scholar 

  83. Bridoux V, Regimbeau JM, Ouaissi M, et al. Hartmann’s procedure or primary anastomosis for generalized peritonitis due to perforated diverticulitis: a prospective multicenter randomized trial (DIVERTI). J Am Coll Surg. 2017;225:798–805.

    PubMed  Google Scholar 

  84. Lambrichts DPV, Vennix S, Musters GD, et al. Hartmann’s procedure versus sigmoidectomy with primary anastomosis for perforated diverticulitis with purulent or faecal peritonitis (LADIES): a multicentre, parallel-group, randomised, open-label, superiority trial. Lancet Gastroenterol Hepatol. 2019;4:599–610.

    PubMed  Google Scholar 

  85. Lee JM, Chang JBP, El Hechi M, et al. Hartmann’s procedure vs primary anastomosis with diverting loop ileostomy for acute diverticulitis: nationwide analysis of 2,729 emergency surgery patients. J Am Coll Surg. 2019;229:48–55.

    PubMed  Google Scholar 

  86. Cirocchi R, Afshar S, Shaban F, et al. Perforated sigmoid diverticulitis: Hartmann’s procedure or resection with primary anastomosis-a systematic review and meta-analysis of randomised control trials. Tech Coloproctol. 2018;22:743–753.

    PubMed  Google Scholar 

  87. Tartaglia D, Costa G, Camillò A, et al. Damage control surgery for perforated diverticulitis with diffuse peritonitis: saves lives and reduces ostomy. World J Emerg Surg. 2019;14:19.

    PubMed  PubMed Central  Google Scholar 

  88. Sohn M, Agha A, Heitland W, et al. Damage control strategy for the treatment of perforated diverticulitis with generalized peritonitis. Tech Coloproctol. 2016;20:577–583.

    CAS  PubMed  Google Scholar 

  89. Nagata N, Ishii N, Manabe N, et al. Guidelines for colonic diverticular bleeding and colonic diverticulitis: Japan Gastroenterological Association. Digestion. 2019;99:1–26.

    PubMed  Google Scholar 

  90. van Dijk ST, Chabok A, Dijkgraaf MG, et al. Observational versus antibiotic treatment for uncomplicated diverticulitis: an individual-patient data meta-analysis. Br J Surg. 2020;107:1062–1069.

    PubMed  PubMed Central  Google Scholar 

  91. Moya P, Bellon M, Arroyo A, et al. Outpatient treatment in uncomplicated acute diverticulitis: 5-year experience. Turk J Gastroenterol. 2016;27:330–335.

    PubMed  Google Scholar 

  92. Biffl WL, Moore FA, Moore EE. What is the current role of laparoscopic lavage in perforated diverticulitis? J Trauma Acute Care Surg. 2017;82:810–813.

    PubMed  PubMed Central  Google Scholar 

  93. Dossa F, Acuna SA, Baxter NN, et al. Optimal operative strategy for hinchey iii sigmoid diverticulitis: a decision analysis. Dis Colon Rectum. 2020;10:1097.

    Google Scholar 

  94. Lambrichts DP, Edomskis PP, van der Bogt RD, et al. Sigmoid resection with primary anastomosis versus the Hartmann’s procedure for perforated diverticulitis with purulent or fecal peritonitis: a systematic review and meta-analysis. Int J Colorectal Dis. 2020;35:1371–1386.

    PubMed  PubMed Central  Google Scholar 

  95. Li D, Baxter NN, McLeod RS, et al. The decline of elective colectomy following diverticulitis: a population-based analysis. Dis Colon Rectum. 2016;59:332–339.

    PubMed  Google Scholar 

  96. Roig JV, Sánchez-Guillén L, García-Armengol JJ. Acute diverticulitis and surgical treatment. Minerva Chir. 2018;73:163–178.

    PubMed  Google Scholar 

  97. Andersen JC, Bundgaard L, Elbrønd H, et al. Danish national guidelines for treatment of diverticular disease. Dan Med J. 2012;59:C4453.

    PubMed  Google Scholar 

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We wish to thank Ms. Claudia CIRILLO for her English language editing of our text.

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Lauro, A., Pozzi, E., Vaccari, S. et al. Drains, Germs, or Steel: Multidisciplinary Management of Acute Colonic Diverticulitis. Dig Dis Sci 65, 3463–3476 (2020). https://doi.org/10.1007/s10620-020-06621-8

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