Digestive Diseases and Sciences

, Volume 63, Issue 5, pp 1363–1365 | Cite as

Heterotopic Pancreas: A Rare Cause of Gastrointestinal Bleeding in Children

  • Lucy Henderson
  • Shawqui Nour
  • Haitham Dagash
Case Report


Heterotopic pancreas is a rare condition of aberrant/ectopic pancreatic tissue with no anatomical or vascular connection to the pancreas. Symptomatic presentation in children is unusual. We discuss two cases presenting with upper gastrointestinal (GI) bleeding. After extensive investigation, both were subsequently found to have gastric antral pancreatic heterotopia.

Case 1

A 4-month-old male infant presented with an acute history of hematemesis and malena. Clinical examination and baseline blood tests including full blood count (FBC) and clotting profile were normal. A working diagnosis of gastroesophageal reflux (GER) with possible cow’s milk protein intolerance (CMPI) was made, and the child was discharged home on a cow’s milk exclusion diet and oral Ranitidine.

At 9 months, the patient presented with further hematemesis, diarrhea, and weight loss. Stool culture was negative for infection. IgE levels were normal; celiac and cystic fibrosis screenings were negative. He...


Heterotopic pancreas Malena Hematemesis Gastrointestinal (GI) bleeding Esophagogastroduodenoscopy (EGD) Video capsule endoscopy 


Author's contribution

Each author has substantially contributed to the manuscript and approved the final version.

Compliance with ethical standards

Conflict of interest

The authors have no conflicts of interest to disclose.


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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Department of Pediatric SurgeryLeicester Royal InfirmaryLeicesterUK

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