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Gastric Electrical Stimulation and Sacral Electrical Stimulation: A Long-Term Follow-Up Study of Dual-Device Treatment

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Abstract

Aims

The objective of this study was to investigate sacral electrical stimulation (SES) and gastric electrical stimulation (GES) by comparing upper and lower gastrointestinal (GI) and genitourinary (GU) symptoms and quality of life, before treatment and in the long term after treatment. We hypothesized that dual-device treatment would greatly improve upper and lower gastrointestinal and genitourinary symptoms, as well as quality of life.

Methods

Fifty-four patients who underwent dual-device treatment (GES and SES) were enrolled in this study. Patients who had surpassed 24 months since the second-device insertion were included. Patients were evaluated before and after both devices were implanted and given a symptom questionnaire regarding their upper GI, lower GI, and GU symptoms and their quality of life.

Results

With combined treatment, a statistically significant improvement was seen in upper GI, lower GI, and GU symptoms and quality of life. However, fecal incontinence and fecal urgency improvements did not reach statistical significance, likely due to the small sample size.

Conclusion

The implantation of two stimulators appears to be safe and effective to improve patients’ quality of life for those with upper GI symptoms, bowel problems, and bladder dysfunction.

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Acknowledgments

The authors would like to acknowledge the following people for their contribution to this study: Paige White, MD, Roger Dmochowski, MD, William Duncan, MD, Charles L Secrest, MD, John Brizzolara, MD, Howard Goldman, MD, Amar Al-Juburi, MD, Danielle Spree FNP, and Catherine McBride.

Author information

Authors and Affiliations

  1. Division of Female Pelvic Medicine & Reconstructive Surgery, Department of Obstetrics and Gynecology, University of Louisville, Louisville, KY, USA

    Anubhav Agrawal, Sean Lamar Francis & Nicolette Elizabeth Deveneau

  2. St. Francis Women’s Health Center, Federal Way, WA, USA

    Shaily Jain

  3. White-Wilson Medical Center, Fort Walton Beach, FL, USA

    Christopher Abrasley

  4. GI Associates, Jackson, MS, USA

    Jason Trippe McNeese

  5. University of Rochester Medical Center and Strong Memorial Hospital, Rochester, NY, USA

    Shivangi T. Kothari

  6. University of Mississippi, Jackson, MS, USA

    Christopher J. Lahr

  7. Division of Gastroenterology, Hepatology and Nutrition, Department of Medicine, University of Louisville, 550 S. Jackson Street, ACB A3L15, Louisville, KY, 40202, USA

    Thomas L. Abell

Authors
  1. Anubhav Agrawal
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  2. Sean Lamar Francis
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  3. Nicolette Elizabeth Deveneau
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  4. Shaily Jain
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  5. Christopher Abrasley
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  6. Jason Trippe McNeese
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  7. Shivangi T. Kothari
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  8. Christopher J. Lahr
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  9. Thomas L. Abell
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Corresponding author

Correspondence to Thomas L. Abell.

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Conflict of interest

Dr. Abell has been a consultant, investigator, and licensor to Medtronic.

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Agrawal, A., Francis, S.L., Deveneau, N.E. et al. Gastric Electrical Stimulation and Sacral Electrical Stimulation: A Long-Term Follow-Up Study of Dual-Device Treatment. Dig Dis Sci 61, 176–180 (2016). https://doi.org/10.1007/s10620-015-3840-4

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  • DOI: https://doi.org/10.1007/s10620-015-3840-4

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