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Probiotics Are Sensitive Microorganisms: Lactobacillus Can Be Affected by Stomach Acid, Antibiotic, and Bowel Cleansing

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References

  1. Mangell P, Thorlacius H, Syk I, et al. Lactobacillus plantarum 299v does not reduce enteric bacteria or bacterial translocation in patients undergoing colon resection. Dig Dis Sci. 2012 Mar 21;57:1915–1924. doi:10.1007/s10620-012-2102-y.

  2. Söderlind E, Dressman JB. Physiological factors affecting drug release and absorption in the gastrointestinal tract. In: Dressman JB, Reppas C, eds. Oral Drug Absorption: Prediction and Assessment, 2nd ed. Drugs and the Pharmaceutical Sciences, vol. 193. New York: Informa Healthcare USA, Inc; 2010:1–20.

  3. Vertzoni M, Dressman J, Butler J, Hempenstall J, Reppas C. Simulation of fasting gastric conditions and its importance for the in vivo dissolution of lipophilic compounds. Eur J Pharm Biopharm. 2005;60:413–417.

    Article  PubMed  CAS  Google Scholar 

  4. Jantratid E, Janssen N, Reppas C, Dressman JB. Dissolution media simulating conditions in the proximal human gastrointestinal tract: an update. Pharm Res. 2008;25:1663–1676.

    Article  PubMed  CAS  Google Scholar 

  5. Sohail A, Turner MS, Coombes A, Bostrom T, Bhandari B. Survivability of probiotics encapsulated in alginate gel microbeads using a novel impinging aerosols method. Int J Food Microbiol. 2011;145:162–168.

    Article  PubMed  CAS  Google Scholar 

  6. Johansson M-L, Nobaek S, Berggren A, et al. Survival of Lactobacillus plantarum DSM 9843 (299v), and effect on the short chain fatty acid content of faeces after ingestion of a rose-hip drink with fermented oats. Int J Food Microbiol. 1998;42:29–38.

    Article  PubMed  CAS  Google Scholar 

  7. Goossens D, Jonkers D, Russel M, et al. Survival of the probiotic, L. plantarum 299v and its effects on the faecal bacterial flora, with and without gastric acid inhibition. Dig Liver Dis. 2005;37:44–50.

    Article  PubMed  CAS  Google Scholar 

  8. Klarin B, Johansson ML, Molin G, Larsson A, Jeppsson B. Adhesion of the probiotic bacterium Lactobacillus plantarum 299v onto the gut mucosa in critically ill patients: a randomised open trial. Crit Care. 2005;9:R285–R293.

    Article  PubMed  Google Scholar 

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Authors and Affiliations

  1. Department of Gastroenterology, Cumhuriyet University, Sivas, Turkey

    Hakan Alagozlu

  2. Department of Gastroenterology, Gazi University, Ankara, Turkey

    Tarkan Karakan

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  1. Hakan Alagozlu
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  2. Tarkan Karakan
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Correspondence to Hakan Alagozlu.

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Alagozlu, H., Karakan, T. Probiotics Are Sensitive Microorganisms: Lactobacillus Can Be Affected by Stomach Acid, Antibiotic, and Bowel Cleansing. Dig Dis Sci 57, 2477–2478 (2012). https://doi.org/10.1007/s10620-012-2310-5

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  • DOI: https://doi.org/10.1007/s10620-012-2310-5

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