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Digestive Diseases and Sciences

, Volume 57, Issue 5, pp 1130–1133 | Cite as

Gastrointestinal Dysmotility

  • Ashish Nimgaonkar
  • Jung W. Choi
  • Linda Nguyen
  • George TriadafilopoulosEmail author
Stanford Multidisciplinary Seminars

Case Presentation and Evolution

A 42 year-old previously healthy man was admitted to Stanford University hospital because of severe nausea and vomiting. He had been well until 3 weeks before admission, when he first experienced nausea, vomiting, and profound sweating without chills or fever, lasting up to 24 h. The symptoms became progressively worse and occurred with any oral intake of solids or liquids. He also noted the sensation of food being stuck in his throat despite swallowing small bites.

An upper endoscopy that had been performed at another hospital showed a small hiatal hernia, antral and gastric body erythema, and gastric food retention. At that time, an abdomen CT scan revealed mild bowel wall thickening in the distal ileum. His symptoms had gradually improved and he was discharged. However, soon thereafter, his symptoms worsened to the point that he could no longer tolerate either solids or liquids and he was admitted to Stanford hospital. In the course of the three weeks...

Keywords

Achalasia Lower Esophageal Sphincter Gastroparesis Gastrointestinal Dysmotility Intestinal Dysmotility 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

  1. 1.
    Stanghellini V, Camilleri M, Malagelada JR. Chronic idiopathic intestinal pseudo-obstruction: clinical and intestinal manometric findings. Gut. 1987;28:5–12.PubMedCrossRefGoogle Scholar
  2. 2.
    Rosa-E-Silva L, Gerson L, Davila M, Triadafilopoulos G. Clinical, radiologic, and manometric characteristics of chronic intestinal dysmotility: the Stanford experience. Clin Gastroenterol Hepatol. 2006;4:866–873.PubMedCrossRefGoogle Scholar
  3. 3.
    Di Nardo G, Blandizzi C, Volta U, et al. Review article: molecular, pathological and therapeutic features of human enteric neuropathies. Aliment Pharmacol Ther. 2008;28:25–42.PubMedCrossRefGoogle Scholar
  4. 4.
    Sigala S, Missale G, Missale C, et al. Different neurotransmitter systems are involved in the development of esophageal achalasia. Life Sci. 1995;56:1311–1320.PubMedCrossRefGoogle Scholar
  5. 5.
    Pasricha PJ, Ravich WJ, Hendrix TR, Sostre S, Jones B, Kalloo AN. Intra-sphincteric botulinum toxin for the treatment of achalasia. N Engl J Med. 1995;332:774–778. Erratum in: N Engl J Med. 1995;333:75.Google Scholar
  6. 6.
    Pasricha PJ, Rai R, Ravich WJ, Hendrix TR, Kalloo AN. Botulinum toxin for achalasia: long-term outcome and predictors of response. Gastroenterology. 1996;110:1410–1415.PubMedCrossRefGoogle Scholar
  7. 7.
    Kopelman Y, Triadafilopoulos G. Endoscopy in the diagnosis and management of motility disorders. Dig Dis Sci. 2011;56:635–654.PubMedCrossRefGoogle Scholar
  8. 8.
    Hasler WL. Gastroparesis: pathogenesis, diagnosis and management. Nat Rev Gastroenterol Hepatol. 2011;8:438–453.PubMedCrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media, LLC 2011

Authors and Affiliations

  • Ashish Nimgaonkar
    • 1
  • Jung W. Choi
    • 2
  • Linda Nguyen
    • 1
  • George Triadafilopoulos
    • 1
    Email author
  1. 1.Division of Gastroenterology and HepatologyStanford University HospitalStanfordUSA
  2. 2.Department of RadiologyMoffitt Cancer CenterTampaUSA

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