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Digestive Diseases and Sciences

, Volume 55, Issue 6, pp 1610–1614 | Cite as

Heartburn and Regurgitation in Pregnancy: The Effect of Fat Ingestion

  • Valesca Dall’Alba
  • Fernando FornariEmail author
  • Cláudio Krahe
  • Sidia Maria Callegari-Jacques
  • Sérgio Gabriel  Silva de Barros
Original Article

Abstract

Background

Reflux symptoms are common in pregnancy, but their association with fat ingestion is unclear.

Aim

To investigate an association of dietary fats with heartburn and regurgitation in pregnancy.

Methods

This is a prospective study in which 89 pregnant women (gestational age 34 ± 4 weeks) attending a low-risk prenatal outpatient clinic were asked to provide information on the frequency they experienced heartburn and regurgitation. Fat ingestion was estimated by means of a 24-h diet record. Symptomatic patients were compared with those with no reflux symptoms (n = 20).

Results

Heartburn once a week or more often occurred in 56 of the 89 patients (63%). The ingested amount of polyunsaturated fatty acids was higher in patients with heartburn (11.2 ± 6.4 vs. 7.7 ± 3.5 mg; P = 0.022) than in controls after adjusting for age, gain weight during pregnancy, ingestion of caffeine and vitamin C, and total energetic intake. The ingestion of monounsaturated fatty acids was higher in patients with heartburn, but with a borderline statistical significance (16.1 ± 11 vs. 11.8 ± 6.5 mg; P = 0.061). No association was observed between the consumption of fats and regurgitation.

Conclusions

This study suggests that heartburn in the third trimester of pregnancy is associated with the ingestion of polyunsaturated fatty acids.

Keywords

Dietary fats Fatty acids Gastroesophageal reflux disease Heartburn Pregnancy 

Notes

Acknowledgments

This study was supported by grants from Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES), Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq), and Fundo de Incentivo à Pesquisa e Eventos (FIPE)/Hospital de Clínicas de Porto Alegre, Brazil.

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Copyright information

© Springer Science+Business Media, LLC 2009

Authors and Affiliations

  • Valesca Dall’Alba
    • 1
  • Fernando Fornari
    • 1
    • 2
    Email author
  • Cláudio Krahe
    • 3
  • Sidia Maria Callegari-Jacques
    • 4
  • Sérgio Gabriel  Silva de Barros
    • 1
  1. 1.Post-Graduate Program, Sciences in Gastroenterology, School of Medicine and Hospital de Clinicas de Porto AlegreUniversidade Federal do Rio Grande do Sul (UFRGS)Porto AlegreBrazil
  2. 2.School of MedicineUniversidade de Passo FundoPasso FundoBrazil
  3. 3.Department of Gynecology, School of MedicinePontifícia Universidade Católica do Rio Grande do Sul (PUC-RS)Porto AlegreBrazil
  4. 4.Department of Statistics and Post-Graduate Program in Genetics and Molecular BiologyUFRGSPorto AlegreBrazil

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