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Clinical Outcomes and Patency of Self-expanding Metal Stents in Patients with Malignant Upper Gastrointestinal Obstruction

Digestive Diseases and Sciences volume 53, pages 938–945 (2008)Cite this article

Abstract

This study was performed to evaluate clinical outcomes and factors associated with patency of self-expanding metal stents (SEMS) in patients with malignant upper gastrointestinal (UGI) obstruction. In 83 patients with malignant UGI obstruction, 118 SEMS placements were performed. Obstruction sites were esophagus/gastro-esophageal junction (GEJ) and gastric outlet (GO) in 41 and 42 patients, respectively. Technical success was achieved in 99.2% and clinical success in 90.5%, with no procedure-related complications. Re-obstruction and migration occurred in 38.1% during a mean follow-up of 137 days; both occurred significantly more often with GO than esophageal/GEJ obstruction (49.2% vs 23.9%). Patency rates of esophageal/GEJ obstruction were 93.5, 78.1 and 67.0% at 30, 90 and 180 days, respectively, and were significantly higher than those of GO obstruction—71.7, 51.8 and 32.5%. Palliative chemotherapy or radiation therapy was not associated with stent patency. Endoscopic SEMS placement is a safe and effective palliative treatment for malignant UGI obstruction, and complications or stent patency differed according to obstruction site.

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Affiliations

  1. Department of Internal Medicine and Liver Research Institute, Seoul National University College of Medicine, 28 Yongon-dong, Chongno-gu, Seoul, 110-744, Republic of Korea

    Jong Pil Im, Jung Mook Kang, Sang Gyun Kim, Joo Sung Kim, Hyun Chae Jung & In Sung Song

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  1. Jong Pil Im
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  2. Jung Mook Kang
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  3. Sang Gyun Kim
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Correspondence to Sang Gyun Kim.

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Im, J.P., Kang, J.M., Kim, S.G. et al. Clinical Outcomes and Patency of Self-expanding Metal Stents in Patients with Malignant Upper Gastrointestinal Obstruction. Dig Dis Sci 53, 938–945 (2008). https://doi.org/10.1007/s10620-007-9967-1

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  • DOI: https://doi.org/10.1007/s10620-007-9967-1

Keywords

  • Esophageal cancer
  • Gastric cancer
  • Malignant obstruction
  • Self-expanding metal stents
  • Patency