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Novel Biodegradable Stents for Benign Esophageal Strictures Following Endoscopic Submucosal Dissection

Digestive Diseases and Sciences volume 53, pages 330–333 (2008)Cite this article

Abstract

The application of metallic stents for benign stenosis is limited due to long-term complications. We report here the results of the implantation of a novel biodegradable poly-l-lactic acid (PLLA) esophageal stent in two patients with benign esophageal stenosis after endoscopic submucosal dissection (ESD). Case 1 was a 64-year-old man who received ESD for an early squamous esophageal cancer in the middle esophagus. The mucosal defect was seven-eighths of the circumference, and the distal margin of the resection scar formed the stenosis. After balloon dilatation, the PLLA esophageal stent was endoscopically placed; for 6 months, he has not experienced any symptoms of re-stenosis. Case 2 consisted of a 62-year-old man who developed an early squamous esophageal cancer in the middle esophagus. The lesion was resected by ESD, and the mucosal defect was seven-eighths of the circumference. The resection scar formed the stenosis, and the PLLA esophageal stent was endoscopically placed. He also has not experienced any symptoms of re-stenosis for 6 months. In conclusion, the PLLA esophageal stent provides a new possibility for the management of benign esophageal strictures after ESD. Due to the biodegradable features of this stent, longer term studies are necessary to investigate the relationship between the expected disappearance of the stent and the patency of the stricture.

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Affiliations

  1. Department of Endoscopic Medicine, Shiga University of Medical Science, Seta Tukinowa, Otsu, 520-2192, Japan

    Yasuharu Saito

  2. Department of Radiology, Shiga University of Medical Science, Seta Tukinowa, Otsu, 520-2192, Japan

    Toyohiko Tanaka, Norihisa Nitta & Kiyoshi Murata

  3. Department of Internal Medicine, Shiga University of Medical Science, Seta Tukinowa, Otsu, 520-2192, Japan

    Akira Andoh, Hideki Minematsu, Kazunori Hata, Tomoyuki Tsujikawa & Yoshihide Fujiyama

Authors
  1. Yasuharu Saito
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  2. Toyohiko Tanaka
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  3. Akira Andoh
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  4. Hideki Minematsu
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  5. Kazunori Hata
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  6. Tomoyuki Tsujikawa
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  7. Norihisa Nitta
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  8. Kiyoshi Murata
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  9. Yoshihide Fujiyama
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Correspondence to Yasuharu Saito.

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Saito, Y., Tanaka, T., Andoh, A. et al. Novel Biodegradable Stents for Benign Esophageal Strictures Following Endoscopic Submucosal Dissection. Dig Dis Sci 53, 330–333 (2008). https://doi.org/10.1007/s10620-007-9873-6

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  • DOI: https://doi.org/10.1007/s10620-007-9873-6

Keywords

  • Benign stricture
  • Endoscopic submucosal dissection
  • Poly-l-lactic acid