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Chylous Ascites Secondary to Pancreatitis: Management of an Uncommon Entity Using Parenteral Nutrition and Octreotide

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Abstract

Malignancy, surgical trauma, cirrhosis and tuberculosis account for more than 95% of causes for chylous ascites. We report a case of persistent chylous ascites following acute pancreatitis that responded to parenteral nutrition and octreotide. A 50 year-old male was diagnosed with acute alcoholic pancreatitis after presenting with typical abdominal pain, and elevated amylase and lipase. The acute symptoms resolved within one week. Four weeks later he started developing increased abdominal girth. Examination revealed the presence of shifting dullness and paracentesis confirmed diagnosis of chylous ascites. Investigations for the common causes of chylous ascites were negative. Laparoscopy confirmed the presence of fat necrosis within mesenteric lymph nodes linking the chylous ascites to the episode of pancreatitis. The Chylous ascites was resistant to the usual medical therapy, but responded only to the combination of octreotide and total parenteral nutrition with complete resolution of ascites in 8 weeks. This case of chylous ascites secondary to pancreatitis represents an uncommon presentation with effective management resulting in a dramatic response.

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References

  1. Aalami OO, Allen DB, Organ Jr CH (2000) Chylous ascites: collective review. Surgery 128:761–78

    Article  PubMed  CAS  Google Scholar 

  2. Cardenas A, Chopra S (2002) Chylous ascites. Am J Gastroenterol 97:1896–1900

    PubMed  Google Scholar 

  3. Browse NL, Wilson NM, Russo F, Al-Hassan H, Allen DR (1992) Aetiology and treatment of chylous ascites. Br J Surg 79:1145–1150

    Article  PubMed  CAS  Google Scholar 

  4. Sultan S, Pauwels A, Poupon R, Levy VG (1990) Chylous ascites in cirrhosis: retrospective study of 20 cases. Gastroenterol Clin Biol 14:842–847

    PubMed  CAS  Google Scholar 

  5. Casafont F, Lopez-Arias MJ, Crespo J, Duenas C, Sanchez-Antolin G, Rivero M, Pons Romero F (1997) Chylous ascites in cirrhotic and non-cirrhotic patients. Gastroenterol Hepatol 20:291–294

    PubMed  CAS  Google Scholar 

  6. Press OW, Press NO, Kaufman SD (1982) Evaluation and management of chylous ascites. Ann Intern Med 96:358–364

    PubMed  CAS  Google Scholar 

  7. Leibovitch I, Mor Y, Golomb J, Ramon J (2002) The diagnosis and management of postoperative chylous ascites. J Urol 167:449–457

    Article  PubMed  Google Scholar 

  8. Chu CM, Lin SM, Peng SM, Wu CS, Liaw YF (1994) The role of laparoscopy in the evaluation of ascites of unknown origin. Gastrointest Endosc 40:285–289

    Article  PubMed  CAS  Google Scholar 

  9. Poux JM, Benevent D, Guiserix J, Le Meur Y, Lagarde C, Leroux-Robert C (1994) Chylous ascites in 12 patients undergoing peritoneal dialysis. Nephrologie 15:201–205

    PubMed  CAS  Google Scholar 

  10. Fourdan O, Levy P, Sauvanet A, Bernades P (1993) A case of chylous ascites associated with exudative enteropathy complicating chronic pancreatitis of alcoholic origin. Gastroenterol Clin Biol 17:53–55

    Article  PubMed  CAS  Google Scholar 

  11. Gekas PM, Nikoomanesh P, Smith GW (1979) Pancreatic ascites: a rare complication of distal splenorenal shunt. Am J Surg 138:710–712

    Article  PubMed  CAS  Google Scholar 

  12. Collery P, Coudoux P, Geoffroy H (1978) Chylous ascites and chronic pancreatitis. Med Chir Dig 7:9–13

    PubMed  CAS  Google Scholar 

  13. Blanchon P, Hivet M, Naudin G, Holler A (1972) Chronic pancreatitis and chylous ascites. Discussion of a case. Ann Med Interne (Paris) 123:491–495

    CAS  Google Scholar 

  14. Bragard M, Paraf A, Caroli J (1961) Apropos of a case of chylous ascites in an adult secondary to chronic pancreatitis. Rev Med Chir Mal Foie 36:194–202

    PubMed  CAS  Google Scholar 

  15. Gambill EE, Walters W, Scanlon PW (1960) Chronic relapsing pancreatitis with extensive subacute peritonitis and chronic, recurrent massive “chylous” ascites. Am J Med 28:668–670

    Article  PubMed  CAS  Google Scholar 

  16. Goldfarb JP (1984) Chylous effusions secondary to pancreatitis: case report and review of the literature. Am J Gastroenterol 79:133–135

    PubMed  CAS  Google Scholar 

  17. Perez Fontan M, Pombo F, Soto A, Perez Fontan FJ, Rodriguez-Camerona A (1993) Chylous ascites associated with acute pancreatitis in a patient undergoing continuous ambulatory peritoneal dialysis. Nephron 63:458–461

    Article  PubMed  CAS  Google Scholar 

  18. Ben-Ami H, Nagachandran P, Assalia A, Edoute Y (1999) Acute transient chylous ascites associated with acute biliary pancreatitis. Am J Med Sci 318:122–123

    Article  PubMed  CAS  Google Scholar 

  19. Zhang ZY, Howard JM (1997) Chylous ascites: a late complication of massive peripancreatic necrosis. Int J Pancreatol 21:259–261

    PubMed  CAS  Google Scholar 

  20. Liu CJ, Yen CL, Chang JJ, Lee TS, Fan KM (2001) Chylous ascites in acute pancreatitis during pregnancy: case report. Chang Gung Med J 24:324–328

    PubMed  CAS  Google Scholar 

  21. Lee PC, Howard JM (1979) Fat necrosis. Surg Gynecol Obstet 148:785–789

    PubMed  CAS  Google Scholar 

  22. Collard JM, Laterre PF, Boemer F, Reynaert M, Ponlot R (2000) Conservative treatment of postsurgical lymphatic leaks with somatostatin-14. Chest 117:902–905

    Article  PubMed  CAS  Google Scholar 

  23. Shapiro AM, Bain VG, Sigalet DL, Kneteman NM (1996) Rapid resolution of chylous ascites after liver transplantation using somatostatin analog and total parenteral nutrition. Transplantation 61:1410–1411

    Article  PubMed  CAS  Google Scholar 

  24. Rimensberger PC, Muller-Schenker B, Kalangos A, Beghetti M (1998) Treatment of a persistent postoperative chylothorax with somatostatin. Ann Thorac Surg 66:253–254

    Article  PubMed  CAS  Google Scholar 

  25. Reubi JC, Horisberger U, Waser B, Gebbers JO, Laissue J (1992) Preferential location of somatostatin receptors in germinal centers of human gut lymphoid tissue. Gastroenterology 103:1207–1214

    PubMed  CAS  Google Scholar 

  26. Kroczek RA (1985) Congenital chyloperitoneum: direct comparison of medium-chain triglyceride treatment with total parenteral nutrition. Eur J Pediatr 144:77–79

    Article  PubMed  CAS  Google Scholar 

  27. Lee YY, Soong WJ, Lee YS, Hwang B (2002) Total parenteral nutrition as a primary therapeutic modality for congenital chylous ascites: report of one case. Acta Paediatr Taiwan 43:214–216

    PubMed  Google Scholar 

  28. Alliet P, Young C, Lebenthal E (1992) Chylous ascites: total parenteral nutrition as primary therapeutic modality. Eur J Pediatr 151:213–214

    Article  PubMed  CAS  Google Scholar 

  29. Huang Q, Jiang ZW, Jiang J, Li N, Li JS (2004) Chylous ascites: treated with total parenteral nutrition and somatostatin. World J Gastroenterol 10:2588–2591

    PubMed  CAS  Google Scholar 

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Correspondence to Kevork M. Peltekian MD.

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Al-Ghamdi, M.Y., Bedi, A., Reddy, S.B. et al. Chylous Ascites Secondary to Pancreatitis: Management of an Uncommon Entity Using Parenteral Nutrition and Octreotide. Dig Dis Sci 52, 2261–2264 (2007). https://doi.org/10.1007/s10620-006-9734-8

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  • DOI: https://doi.org/10.1007/s10620-006-9734-8

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