Abstract
Ileal idiopathic forms of ganglioneuromatosis in adults are extremely rare and represent a challenging pathologic condition for the clinician. We present two cases of ileal ganglioneuromatosis consisting of stricturing lesions that mimicked clinical and radiologic features commonly observed in Crohn’s disease patients with ileal involvement.
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Smith VV, Eng C, Milla PJ (1999) Intestinal ganglioneuromatosis and multiple endocrine neoplasia type 2B: implications fit treatment. Gut 45:143–146
Carney JA, Go VL, Sizemore GW, Hayles AB (1976) Alimentary-tract ganglioneuromatosis. A major component of the syndrome of multiple endocrine neoplasia, type 2. N Engl J Med 295:1287–1291
Shekitka KM, Sobin LH (1994) Ganglioneuromas of the gastrointestinal tract. Relation to Von Recklinghausen disease and other multiple tumor syndromes. Am J Surg Pathol 18(3):250–257
Raszkowski HJ, Hufner RF (1971) Neurofibromatosis of the colon: a unique manifestation of von Recklinghausen’s disease. Cancer 27:134–142
d’Amore ES, Manivel JC, Pettinato G, Niehans GA, Snover DC (1991) Intestinal ganglioneuromatosis: mucosal and transmural types. A clinicopathologic and immunohistochemical study of six cases. Hum Pathol 22:276–286
Chambonniere ML, Porcheron J, Scoazec JY, Audigier JC, Mosnier JF (2003) Intestinal ganglioneuromatosis diagnosed in adult patients. Gastroenterol Clin Biol 27:219–224
Lashner BA, Riddell RH, Winans CS (1986) Ganglioneuromatosis of the colon and extensive glycogenic acanthosis in Cowden’s disease. Dig Dis Sci 31:213–216
Mendelsohn G, Diamonds MP (1984) Familial ganglioneuromatosis polyposis of the large bowel. Report of a family with associated juvenile polyposis. Am J Surg Pathol 8:515–520
Macenlle R, Fernandez-Seara J, Pato M, Pereira J, Pascual P, Montero M, Miranda C (1999) Ganglioneuromatous polyposis of the colon associated with adenocarcinoma and primary hyperparathyroidism. Eur J Gastroenterol Hepatol 11:447–450
Charagundla SR, Levine MS, Torigian DA, Campbell MS, Furth EE, Rombeau J (2004) Diffuse intestinal ganglioneuromatosis mimicking Crohn’s disease. AJR Am J Roentgenol 182:1166–1168
Urbano U, Farina P (1967) Intestinal ganglioneuromatosis in a case of terminal ileitis [in Italian]. Pathologica 59:547–550
Tobler A, Maurer R, Klaiber C (1981) Stenosing ganglioneuromatosis of the small intestine with ileus and ileal rupture [in German]. Schweiz Med Wochenschr 111:684–688
Bernades P, Hecketsweiler P, Benozio M, Descos L, Geffroy Y, Hemet J, Loygue J, Modigliani R, Potet F, Weill JP (1978) Proposal of a system of criteria for the diagnosis of cryptogenetic inflammatory enterocolitis (Crohn’s disease and hemorrhagic rectocolitis). A cooperative study by the Cryptogenic Enterocolitis Study Group. Gastroenterol Clin Biol 2:1047–1054
Rambaud JC (2000) Traité de gastro-entérologie. In: Maladie de Crohn, Gendre JP, Modigliani R (eds). Paris: Flammarion, pp 625–645
Sands BE (2004) From symptom to diagnosis: clinical distinctions among various forms of intestinal inflammation. Gastroenterology 126:1518–1532
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Lorenceau-Savale, C., Savoye, G., Pouzoulet, J. et al. Ganglioneuromatosis: An Unusual Cause of Ileal Stricture Mimicking Crohn’s Disease. Dig Dis Sci 52, 1806–1809 (2007). https://doi.org/10.1007/s10620-006-9603-5
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DOI: https://doi.org/10.1007/s10620-006-9603-5