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Coinfection: Helicobacter pylori/Human Immunodeficiency Virus

Digestive Diseases and Sciences volume 49, pages 1836–1839 (2004)Cite this article

Abstract

To compare H. pylori infection prevalence and gastric mucosa damage in HIV-infected and non-HIV-infected patients, gastric biopsies were systematically taken in 209 individuals who underwent upper Gl endoscopy (102 HIV-infected and 107 non-HIV-infected). H. pylori was found in 42 (41.1%) HIV-infected patients and in 53 (49.5%) non-HIV patients (P=0.22, χ2 = 1.47, NS). In HIV-positive patients infected with H. pylori the mean CD4 count was higher than in HIV-positive patients without H. pylori (364 and 228 cells/mm3, respectively; P = 0.0001). H. pylori gastritis was more severe in the HIV-positive group (χ2 = 15.02, P = 0.0001). The frequency of H. pylori in gastric mucosa in HIV-infected and non-HIV patients was similar. HIV-infected patients with H. pylori had a higher mean CD4 count than HIV-infected individuals without H. pylori. Gastric lesions associated with H. pylori were more severe in the HIV-positive population.

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Affiliations

  1. Division of Gastroenterology, Hospital Fernández, Buenos Aires, Argentina

    Martin Olmos, Valentina Araya, Eduardo Pskorz & Eduardo Coronado Quesada

  2. Division of Pathology, Hospital Fernández, Buenos Aires, Argentina

    Hugo Concetti

  3. Unit of Infectious Diseases, Hospital Fernández, Buenos Aires, Argentina

    Hector Perez & Pedro Cahn

Authors
  1. Martin Olmos
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  2. Valentina Araya
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  3. Eduardo Pskorz
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  4. Eduardo Coronado Quesada
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  5. Hugo Concetti
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  6. Hector Perez
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  7. Pedro Cahn
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Correspondence to Martin Olmos.

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Olmos, M., Araya, V., Pskorz, E. et al. Coinfection: Helicobacter pylori/Human Immunodeficiency Virus. Dig Dis Sci 49, 1836–1839 (2004). https://doi.org/10.1007/s10620-004-9580-5

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  • DOI: https://doi.org/10.1007/s10620-004-9580-5

  • HIV
  • AIDS
  • Helicobacter pylori
  • gastritis