Skip to main content

Advertisement

Log in

Comparing the Efficacy of Competitive Memory Training (COMET) and MEmory Specificity Training (MEST) on Posttraumatic Stress Disorder Among Newly Diagnosed Cancer Patients

  • Original Article
  • Published:
Cognitive Therapy and Research Aims and scope Submit manuscript

Abstract

Background

Cancer has been considered a potentially traumatic experience and is a distinct pathway by which one might develop symptoms of posttraumatic stress disorder (PTSD). This study compared the efficacy of COmpetitive MEmory Training (COMET), an intervention aimed at altering dysfunctional self-representations, and MEmory Specificity Training (MEST), an intervention targeting autobiographical memory deficits, on PTSD and depression symptoms. As a secondary aim, we also investigated the effect of COMET and MEST on trauma-related attentional biases.

Methods

Sixty newly diagnosed cancer patients with PTSD were randomly assigned to either the COMET (n = 30) or MEST groups (n = 30). Each participant completed the Posttraumatic Stress Disorder Checklist-5, Beck Depression Inventory-II and a dot-probe task. The groups then underwent either COMET or MEST. All the assessments were re-conducted after the treatment (post-treatment) and at three months post-treatment (follow-up).

Results

The COMET group had significantly fewer PTSD and depression symptoms compared to the MEST group at post-training and follow-up. Both groups indicated a significant reduction in attentional biases following training.

Conclusions

This study suggests that COMET is a promising brief intervention for the treatment of PTSD in cancer patients.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2
Fig. 3

Similar content being viewed by others

Notes

  1. The data file is available by contacting the corresponding author.

References

  • Ahles, T. A., Root, J. C., & Ryan, E. L. (2012). Cancer-and cancer treatment–associated cognitive change: An update on the state of the science. Journal of Clinical Oncology, 30(30), 3675.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • American Psychiatric Association. (2013). Diagnostic and statistical manual of mental disorders, 5th edition: DSM-5. Arlington, VA: American Psychiatric Association.

    Book  Google Scholar 

  • Australian Centre for Posttraumatic Health. (2013). Australian guidelines for the treatment of acute stress disorder and postraumatic stress disorder. Melbourne, VIC: ACPMH.

    Google Scholar 

  • Beck, A. T., Steer, R. A., & Brown, G. (1996). Beck depression inventory–II. Psychological Assessment.

  • Becker, E. S., & Vrijsen, J. N. (2017). Cognitive processes in CBT. In The Science of Cognitive Behavioral Therapy (pp. 77–106). San Diego, CA: Academic Press.

    Chapter  Google Scholar 

  • Beevers, C. G., Clasen, P. C., Enock, P. M., & Schnyer, D. M. (2015). Attention bias modification for major depressive disorder: Effects on attention bias, resting state connectivity, and symptom change. Journal of Abnormal Psychology, 124(3), 463–475. https://doi.org/10.1037/abn0000049.

    Article  PubMed  PubMed Central  Google Scholar 

  • Berntsen, D., & Rubin, D. C. (2007). When a trauma becomes a key to identity: Enhanced integration of trauma memories predicts posttraumatic stress disorder symptoms. Applied Cognitive Psychology, 21(4), 417–431.

    Article  Google Scholar 

  • Bomyea, J., Johnson, A., & Lang, A. J. (2017). Information processing in PTSD: Evidence for biased attentional, interpretation, and memory processes. Psychopathology Review, 4, 218–243.

    Article  Google Scholar 

  • Bray, F., Ferlay, J., Soerjomataram, I., Siegel, R. L., Torre, L. A., & Jemal, A. (2018). Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA: A Cancer Journal for Clinicians, 68(6), 394–424.

    Google Scholar 

  • Brewin, C. R., Dalgleish, T., & Joseph, S. (1996). A dual representation theory of posttraumatic stress disorder. Psychological Review, 103(4), 670.

    Article  CAS  PubMed  Google Scholar 

  • Brewin, C. R., Gregory, J. D., Lipton, M., & Burgess, N. (2010). Intrusive images in psychological disorders: Characteristics, neural mechanisms, and treatment implications. Psychological Review, 117(1), 210.

    Article  PubMed  PubMed Central  Google Scholar 

  • Bryant, R. A. (2019). Post-traumatic stress disorder: A state-of-the-art review of evidence and challenges. World Psychiatry, 18, 259–269. https://doi.org/10.1002/wps.20656.

  • Buodo, G., Patron, E., Benvenuti, S. M., & Palomba, D. (2018). Single-session attention bias modification training in victims of work-related accidents. Frontiers in Psychology, 9, 1619.

    Article  PubMed  PubMed Central  Google Scholar 

  • Chan, C. M. H., Ng, C. G., Taib, N. A., Wee, L. H., Krupat, E., & Meyer, F. (2018). Course and predictors of post-traumatic stress disorder in a cohort of psychologically distressed patients with cancer: A 4-year follow-up study. Cancer, 124(2), 406–416.

    Article  PubMed  Google Scholar 

  • Cisler, J. M., & Koster, E. H. (2010). Mechanisms of attentional biases towards threat in anxiety disorders: An integrative review. Clinical Psychology Review, 30(2), 203–216.

    Article  PubMed  Google Scholar 

  • Cohen, J. (1988). Statistical power analysis for the behavioral sciences (2nd ed.). Hillsdale, NJ: Erlbaum.

    Google Scholar 

  • Dalgleish, T. (2004). Cognitive approaches to posttraumatic stress disorder: The evolution of multi representational theorizing. Psychological Bulletin, 130(2), 228.

    Article  PubMed  Google Scholar 

  • Desimone, R., & Duncan, J. (1995). Neural mechanisms of selective visual attention. Annual Review of Neuroscience, 18(1), 193–222.

    Article  CAS  PubMed  Google Scholar 

  • Ehlers, A., & Clark, D. M. (2000). A cognitive model of posttraumatic stress disorder. Behaviour Research and Therapy, 38(4), 319–345.

    Article  CAS  PubMed  Google Scholar 

  • Ekkers, W., Korrelboom, K., Huijbrechts, I., Smits, N., Cuijpers, P., & van der Gaag, M. (2011). Competitive memory training for treating depression and rumination in depressed older adults: A randomized controlled trial. Behaviour Research and Therapy, 49(10), 588–596.

    Article  PubMed  Google Scholar 

  • Erten, M. N., & Brown, A. D. (2018). Memory specificity training for depression and posttraumatic stress disorder: A promising therapeutic intervention. Frontiers in Psychology, 9, 419. https://doi.org/10.3389/fpsyg.2018.00419.

    Article  PubMed  PubMed Central  Google Scholar 

  • Esser, P., Glaesmer, H., Faller, H., Koch, U., Härter, M., Schulz, H., et al. (2019). Posttraumatic stress disorder among cancer patients—Findings from a large and representative interview-based study in Germany. Psycho-oncology, 28(6), 1278–1285.

    Article  PubMed  Google Scholar 

  • First, M. B., Williams, J. B. W., Karg, R. S., & Spitzer, R. L. (2015). Structured clinical interview for DSM-5—Research version (SCID-5 for DSM-5, research version; SCID-5-RV) (pp. 1–94). Arlington, VA: American Psychiatric Association.

    Google Scholar 

  • Flory, J. D., & Yehuda, R. (2015). Comorbidity between post-traumatic stress disorder and major depressive disorder: Alternative explanations and treatment considerations. Dialogues in Clinical Neuroscience, 17(2), 141.

    Article  PubMed  PubMed Central  Google Scholar 

  • French-Rosas, L. N., Moye, J., & Naik, A. D. (2011). Improving the recognition and treatment of cancer-related posttraumatic stress disorder. Journal of Psychiatric Practice, 17(4), 270.

    Article  PubMed  PubMed Central  Google Scholar 

  • Ghassemzadeh, H., Mojtabai, R., Karamghadiri, N., & Ebrahimkhani, N. (2005). Psychometric properties of a Persian-language version of the Beck depression inventory-Second edition: BDI-II-PERSIAN. Depression and Anxiety, 21(4), 185–192.

    Article  PubMed  Google Scholar 

  • Gómez de La Cuesta, G., Schweizer, S., Diehle, J., Young, J., & Meiser-Stedman, R. (2019). The relationship between maladaptive appraisals and posttraumatic stress disorder: A meta-analysis. European Journal of Psychotraumatology, 10(1), 1620084. https://doi.org/10.1080/20008198.2019.1620084.

    Article  PubMed  PubMed Central  Google Scholar 

  • Grassi, L., Spiegel, D., & Riba, M. (2017). Advancing psychosocial care in cancer patients. F1000Research, 6, 2083.

    Article  PubMed  PubMed Central  Google Scholar 

  • Gurevich, M., Devins, G. M., & Rodin, G. M. (2002). Stress response syndromes and cancer: Conceptual and assessment issues. Psychosomatics, 43(4), 259–281.

    Article  PubMed  Google Scholar 

  • Hitchcock, C., Werner-Seidler, A., Blackwell, S. E., & Dalgleish, T. (2017). Autobiographical episodic memory-based training for the treatment of mood, anxiety and stress-related disorders: A systematic review and meta-analysis. Clinical Psychology Review, 52, 92–107.

    Article  PubMed  Google Scholar 

  • Jobson, L., Moradi, A. R., Rahimi-Movaghar, V., Conway, M. A., & Dalgleish, T. (2014). Culture and the remembering of trauma. Clinical Psychological Science, 2(6), 696–713.

    Article  Google Scholar 

  • Jobson, L., & O’Kearney, R. (2008). Cultural differences in personal identity in post-traumatic stress disorder. British Journal of Clinical Psychology, 47(1), 95–109.

    Article  PubMed  Google Scholar 

  • Korrelboom, K., de Jong, M., Huijbrechts, I., & Daansen, P. (2009). Competitive memory training (COMET) for treating low self-esteem in patients with eating disorders: A randomized clinical trial. Journal of Consulting and Clinical Psychology, 77(5), 974.

    Article  PubMed  Google Scholar 

  • Korrelboom, K., Gaag, M. V. D., Hendriks, V. M., Huijbrechts, I., & Berretty, E. W. (2008). Treating obsessions with competitive memory training: A pilot study. The Behavior Therapist, 31, 29–36.

    Google Scholar 

  • Korrelboom, K., Marissen, M., & van Assendelft, T. (2011). Competitive memory training (COMET) for low self-esteem in patients with personality disorders: A randomized effectiveness study. Behavioural and Cognitive Psychotherapy, 39(1), 1–19.

    Article  PubMed  Google Scholar 

  • Korrelboom, K., Peeters, S., Blom, S. et al. (2014). Competitive memory training (COMET) for panic and applied relaxation (AR) are equally effective in the treatment of panic in panic-disordered patients. Journal of Contemporary Psychotheraphy, 44, 183–190. https://doi.org/10.1007/s10879-013-9259-3.

  • Korrelboom, K., Visser, S., & Ten Broeke, E. (2004). Gegeneraliseerde angststoornis: wat is het en wat kun je ertegen doen? Dth, 24(4), 143–151.

    Article  Google Scholar 

  • Lange, M., & Joly, F. (2017). How to identify and manage cognitive dysfunction after breast cancer treatment. Journal of Oncology Practice, 13(12), 784–790.

    Article  PubMed  Google Scholar 

  • MacLeod, C., Mathews, A., & Tata, P. (1986). Attentional bias in emotional disorders. Journal of Abnormal Psychology, 95(1), 15.

    Article  CAS  PubMed  Google Scholar 

  • Mehnert, A., & Koch, U. (2007). Prevalence of acute and post-traumatic stress disorder and comorbid mental disorders in breast cancer patients during primary cancer care: A prospective study. Psycho-Oncology: Journal of the Psychological, Social and Behavioral Dimensions of Cancer, 16(3), 181–188.

    Article  Google Scholar 

  • Montesano, A., Feixas, G., Caspar, F., & Winter, D. (2017). Depression and identity: Are self-constructions negative or conflictual? Frontiers in Psychology, 8, 877. https://doi.org/10.3389/fpsyg.2017.00877.

    Article  PubMed  PubMed Central  Google Scholar 

  • Moore, S. A., & Zoellner, L. A. (2007). Overgeneral autobiographical memory and traumatic events: An evaluative review. Psychological Bulletin, 133, 419–437. https://doi.org/10.1037/0033-2909.133.3.419.

  • Moradi, A. R., Moshirpanahi, S., Parhon, H., Mirzaei, J., Dalgleish, T., & Jobson, L. (2014). A pilot randomized controlled trial investigating the efficacy of MEmory Specificity Training in improving symptoms of posttraumatic stress disorder. Behaviour Research and Therapy, 56, 68–74.

    Article  PubMed  Google Scholar 

  • Mousavi, M. E., Samiei, M., Khani, P. M., Pourshahbaz, A., Abbasi, I., Ansari, N., & Aminoroaya, S. (2018). Effective factors of non-adherence and admission in bipolar disorder. Psychology and Behavioral Sciences, 7(6), 97.

    Google Scholar 

  • Myers, J. S. (2013, November). Cancer-and chemotherapy-related cognitive changes: The patient experience. In Seminars in oncology nursing (Vol. 29, pp. 300–307). WB Saunders.

  • Neshat-Doost, H. T., Dalgleish, T., Yule, W., Kalantari, M., Ahmadi, S. J., Dyregrov, A., & Jobson, L. (2013). Enhancing autobiographical memory specificity through cognitive training: An intervention for depression translated from basic science. Clinical Psychological Science, 1(1), 84–92.

    Article  Google Scholar 

  • Niedzwiedz, C. L., Knifton, L., Robb, K. A., Katikireddi, S. V., & Smith, D. J. (2019). Depression and anxiety among people living with and beyond cancer: A growing clinical and research priority. BMC Cancer, 19(1), 1–8.

    Article  Google Scholar 

  • Nieto, M., Navarro-Bravo, B., Moreno, B., Ocana, A., Serrano, J. P., Gras, C. B., et al. (2019). Functioning of autobiographical memory specificity and self-defining memories in people with cancer diagnosis. PeerJ, 7, e8126.

    Article  PubMed  PubMed Central  Google Scholar 

  • Pranjic, N., Bajraktarevic, A., & Ramic, E. (2016). Distress and PTSD in patients with cancer: Cohort study case. Materia Socio-Medica, 28(1), 12.

    Article  PubMed  PubMed Central  Google Scholar 

  • Raes, F., Williams, J. M. G., & Hermans, D. (2009). Reducing cognitive vulnerability to depression: A preliminary investigation of MEmory Specificity Training (MEST) in inpatients with depressive symptomatology. Journal of Behavior Therapy and Experimental Psychiatry, 40(1), 24–38.

    Article  PubMed  Google Scholar 

  • Sadeghi, M., Taghva, A., Goudarzi, N., & Rah Nejat, A. M. (2016). Validity and reliability of Persian version of “post-traumatic stress disorder scale” in war veterans. Iranian Journal of War and Public Health, 8(4), 243–249.

    Google Scholar 

  • Sansom-Daly, U. M., Wakefield, C. E., Robertson, E. G., McGill, B. C., Wilson, H. L., & Bryant, R. A. (2018). Adolescent and young adult cancer survivors’ memory and future thinking processes place them at risk for poor mental health. Psycho-Oncology, 27(12), 2709–2716.

    Article  PubMed  Google Scholar 

  • Schneider, B. C., Wittekind, C. E., Talhof, A., Korrelboom, K., & Moritz, S. (2015). Competitive Memory Training (COMET) for OCD: A self-treatment approach to obsessions. Cognitive Behaviour Therapy, 44(2), 142–152.

    Article  PubMed  Google Scholar 

  • Schottenbauer, M. A., Glass, C. R., Arnkoff, D. B., Tendick, V., & Gray, S. (2008). Nonresponse and dropout rates in outcome studies on PTSD: Review and methodological considerations. Psychiatry: Interpersonal & Biological Processes, 71, 134–168.

    Article  Google Scholar 

  • Siegel, R. L., Miller, K. D., & Jemal, A. (2015). Cancer statistics, 2015. CA: A Cancer Journal for Clinicians, 65(1), 5.

    Google Scholar 

  • Staring, A. B. P., Van den Berg, D. P. G., Cath, D. C., Schoorl, M., Engelhard, I. M., & Korrelboom, C. W. (2016). Self-esteem treatment in anxiety: A randomized controlled crossover trial of Eye Movement Desensitization and Reprocessing (EMDR) versus Competitive Memory Training (COMET) in patients with anxiety disorders. Behaviour Research and Therapy, 82, 11–20.

    Article  CAS  PubMed  Google Scholar 

  • Steel, C., van der Gaag, M., Korrelboom, K., Simon, J., Phiri, P., Baksh, M. F., et al. (2015). A randomised controlled trial of positive memory training for the treatment of depression within schizophrenia. BMC Psychiatry, 15(1), 1–5.

    Article  Google Scholar 

  • Sutherland, K., & Bryant, R. A. (2005). Self-defining memories in post-traumatic stress disorder. British Journal of Clinical Psychology, 44(4), 591–598.

    Article  PubMed  Google Scholar 

  • Van Bockstaele, B., Koster, E. H., Verschuere, B., Crombez, G., & De Houwer, J. (2012). Limited transfer of threat bias following attentional retraining. Journal of Behavior Therapy and Experimental Psychiatry, 43(2), 794–800.

    Article  PubMed  Google Scholar 

  • van der Gaag, M., & Korrelboom, K. (2007). Competitive memory training treatment protocol for voices version 1.

  • van der Gaag, M., van Oosterhout, B., Daalman, K., Sommer, I. E., & Korrelboom, K. (2012). Initial evaluation of the effects of competitive memory training (COMET) on depression in schizophrenia-spectrum patients with persistent auditory verbal hallucinations: A randomized controlled trial. British Journal of Clinical Psychology, 51(2), 158–171.

    Article  PubMed  Google Scholar 

  • Van Minnen, A., Arntz, A., & Keijsers, G. P. (2002). Prolonged exposure in patients with chronic PTSD: predictors of treatment outcome and dropout. Behaviour Research and Therapy, 40, 439–457.

    Article  PubMed  Google Scholar 

  • Verwoerd, J., & Wessel, I. (2010). Unwanted traumatic intrusions: The role of pre-trauma individual differences in executive control. In The act of remembering: Toward an understanding of how we recall the past (pp. 337–360). Malden, MA: Wiley-Blackwell.

    Chapter  Google Scholar 

  • Wald, I., Shechner, T., Bitton, S., Holoshitz, Y., Charney, D. S., Muller, D., et al. (2011). Attention bias away from threat during life threatening danger predicts PTSD symptoms at one-year follow-up. Depression and Anxiety, 28(5), 406–411.

    Article  CAS  PubMed  Google Scholar 

  • Weathers, F. W., Litz, B. T., Keane, T. M., Palmieri, P. A., Marx, B. P., & Schnurr, P. P. (2014, February 5). PTSD Checklist for DSM-5 (PCL-5). National Center for PTSD. Retrieved June 3, 2015, from http://www.ptsd.va.gov/professional/assessment/adult-sr/ptsd-checklist.asp

  • Williams, J. M. G., Barnhofer, T., Crane, C., Hermans, D., Raes, F., Watkins, E., & Dalgleish, T. (2007). Autobiographical memory specificity and emotional disorder. Psychological Bulletin, 133, 122–148. https://doi.org/10.1037/0033-2909.133.1.122.

    Article  PubMed  PubMed Central  Google Scholar 

  • Woud, M. L., Verwoerd, J., & Krans, J. (2017). Modification of cognitive biases related to posttraumatic stress: A systematic review and research agenda. Clinical Psychology Review, 54, 81–95.

    Article  PubMed  Google Scholar 

  • Zia, M. S., Afkhami, E., Taher Neshat-Doost, H., Tavakoli, M., Mehrabi Kooshki, H. A., & Jobson, L. (2020). A brief clinical report documenting a novel therapeutic technique (MEmory Specificity Training, MEST) for depression: A summary of two pilot randomized controlled trials. Behavioural and Cognitive Psychotherapy, 1–6. https://doi.org/10.1017/S1352465820000417. Epub ahead of print. PMID: 32684181.

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Alireza Moradi.

Ethics declarations

Conflict of interest

Sharareh Farahimanesh, Alireza Moradi, Meysam Sadeghi, and Laura Jobson declare there are no conflict of interests.

Research Involving Animal Rights

No animal studies were carried out by the authors for this article.

Additional information

Publisher’s Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Farahimanesh, S., Moradi, A., Sadeghi, M. et al. Comparing the Efficacy of Competitive Memory Training (COMET) and MEmory Specificity Training (MEST) on Posttraumatic Stress Disorder Among Newly Diagnosed Cancer Patients. Cogn Ther Res 45, 918–928 (2021). https://doi.org/10.1007/s10608-020-10175-4

Download citation

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10608-020-10175-4

Keywords

Navigation