Cognitive Therapy and Research

, Volume 38, Issue 2, pp 89–102 | Cite as

Efficacy of Interpretation Bias Modification in Depressed Adolescents and Young Adults

  • Jamie A. Micco
  • Aude Henin
  • Dina R. Hirshfeld-Becker
Original Article


This study evaluated the efficacy of a four-session Cognitive Bias Modification-Interpretation program for 45 depressed adolescents and young adults (14–21 years old; 12 males, 33 females; Beck Depressive Inventory, Second Edition ≥14) randomized to an active intervention condition (repeated exposure to positive outcomes of depression-relevant ambiguous scenarios; n = 23) or a control condition (n = 22). Both conditions experienced reductions on a Test of Interpretation Bias at post-treatment, with no significant between-group differences. When limited to those with negative bias at baseline, the intervention group showed greater improvement in interpretation bias at mid- and post-treatment. In addition, the intervention group overall had greater improvements in self-reported negative cognitions than the control group at post-intervention and two-week follow-up. However, there were no differences between groups in depression or anxiety symptom change. Potential factors contributing to mixed findings are discussed.


Interpretation bias Cognitive bias modification Adolescents Depression 


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Copyright information

© Springer Science+Business Media New York 2013

Authors and Affiliations

  • Jamie A. Micco
    • 1
  • Aude Henin
    • 1
  • Dina R. Hirshfeld-Becker
    • 1
  1. 1.Child Cognitive Behavioral Therapy ProgramMassachusetts General Hospital/Harvard Medical SchoolBostonUSA

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