A new C21-steroidal cynansteroid O (1), together with one new natural product 20-hydroxylateqingyangshengenin (2), and three known compounds (3–5) were isolated from the roots of Cynanchum auriculatum. The chemical structures were elucidated by analyses of physio-chemical properties and spectral data and compared with the published data with given references. Compounds 1–3 were isolated for the first time from the roots of C. auriculatum.
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References
Editorial Committee of Chinese Flora, Flora Reipubl. Popular. Sin. [in China], 63, 309 (1977).
National Health and Family Planning Commission of the People′s Republic of China, NHFPC-approved Seven New Food Materials, Announcement No. 1 [in China], Beijing, 2015, p. 7.
W. H. Chen, Z. Z. Zhang, Y. F. Ban, K. Rahman, B. Z. Ye, X. L. Sun, H. Y. Tan, X. H. Zheng, H. Y. Liu, L. C. Xu, B. Yan, and T. Han, J. Ethnopharmacol., 28 (243), 112110 (2019).
Q. X. Yang, Y. Chang, X. Y. Huang, and Q. Y. Sun, Phytochem. Lett., 4, 170 (2011).
L. Wang, F. J. Cai, W. Zhao, J. L. Tian, D. G. Kong, X. H. Sun, Q. Liu, Y. R. Chen, Y. An, F. L. Wang, X. Liu, Y. Wu, and H. L. Zhou, Molecules, 26 (23), 7065 (2021).
Y. M. Fan, J. Jin, J. Y. Jian, W. Gu, C. M. Yuan, Z. X. Hu, X. J. Hao, and L. J. Huang, Chem. Biodiv., 19, e202200243 (2022).
L. J. Huang, S. R. Chen, C. M, Yuan, W. Gu, B. J. Guo, Y. T. Wang, Y. Wang, and X. J. Hao, Bioorg. Med. Chem., 25 (13), 3512 (2017).
J. Dong, X. Peng, L. Li, S. Lu, L. Zhou, and M. Qiu, Bioorg. Med. Chem. Lett., 28 (9), 1520 (2018).
T. Warashina and T. Noro, Chem. Pharm. Bull., 44, 358 (1996).
T. Warashina and T. Noro, Phytochemistry, 39 (1), 199 (1995).
Acknowledgment
This work was supported by grants from the National Natural Science Foundation of China (31760529 and U1812403), the Natural Science and Technology Foundation of Guizhou Province (QKH foundation-ZK [2021] General 138), and the Natural Science Foundation of Guizhou Province (QKHZYD[2022]4015).
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Published in Khimiya Prirodnykh Soedinenii, No. 3, May–June, 2023, pp. 434–436.
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Huang, Lj., Fan, Ym., Jin, J. et al. A New C21-steroidal Cynansteroid O from Roots of Cynanchum auriculatum. Chem Nat Compd 59, 512–514 (2023). https://doi.org/10.1007/s10600-023-04038-z
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DOI: https://doi.org/10.1007/s10600-023-04038-z